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Stefani Spranger
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Journal Articles

Lung cancer–intrinsic SOX2 expression mediates resistance to checkpoint blockade therapy by inducing Treg cell–dependent CD8+ T-cell exclusion

Elen Torres-Mejia, Sally Weng, Charles A. Whittaker, Kim B. Nguyen, Ellen Duong, Leon Yim, Stefani Spranger
Journal: Cancer Immunology Research
Cancer Immunol Res (2025)
https://doi.org/10.1158/2326-6066.CIR-24-0184
Published: 02 January 2025
View article titled, Lung cancer–intrinsic SOX2 expression mediates resistance to checkpoint blockade therapy by inducing Treg cell–dependent CD8+ T-cell exclusion
Open the PDF for Lung cancer–intrinsic SOX2 expression mediates resistance to checkpoint blockade therapy by inducing Treg cell–dependent CD8+ T-cell exclusion in another window
Includes: Supplementary data
Journal Articles

Abstract A08: Divergent tumor cell states in neuroblastoma possess distinct immunogenic phenotypes

Satyaki Sengupta, Sanjukta Das, Angela C. Crespo, Annelisa M. Cornel, Anand G. Patel, Navin R. Mahadevan, Marco Campisi, Alaa K. Ali, Bandana Sharma, Jared H. Rowe, Rogier Versteeg, Rudolf Jaenisch, Stefani Spranger, Rizwan Romee, Brian C. Miller, David A. Barbie, Stefan Nierkens, Michael A. Dyer, Judy Lieberman, Rani E. George
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (12_Supplement): A08.
https://doi.org/10.1158/2326-6074.TUMIMM22-A08
Published: 01 December 2022
View article titled, Abstract A08: Divergent tumor cell states in neuroblastoma possess distinct immunogenic phenotypes
Journal Articles

Abstract PR010: Potentiating the efficacy of immune checkpoint blockade by targeting the epithelial-to-mesenchymal transition (EMT) in breast carcinomas

Anushka Dongre, Mohammad Rashidian, Elinor Ng Eaton, Ferenc Reinhardt, Prat Thiru, Maria Zagorulya, Sunita Nepal, Tuba Banaz, Anna Martner, Stefani Spranger, Robert A. Weinberg
Journal: Cancer Immunology Research
Cancer Immunol Res (2021) 9 (2_Supplement): PR010.
https://doi.org/10.1158/2326-6074.TUMIMM20-PR010
Published: 03 February 2021
View article titled, Abstract PR010: Potentiating the efficacy of immune checkpoint blockade by targeting the epithelial-to-mesenchymal transition (EMT) in breast carcinomas
Journal Articles

Abstract IA04: Impact of tumor-resident DC on antitumor immunity

Stefani Spranger
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (3_Supplement): IA04.
https://doi.org/10.1158/2326-6074.TUMIMM19-IA04
Published: 02 March 2020
View article titled, Abstract IA04: Impact of tumor-resident DC on antitumor immunity
Journal Articles

Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity

Brendan L. Horton, Jason B. Williams, Alexandra Cabanov, Stefani Spranger, Thomas F. Gajewski
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (1): 14–24.
https://doi.org/10.1158/2326-6066.CIR-17-0249
Published: 02 January 2018
View article titled, Intratumoral CD8<sup>+</sup> T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity
Open the PDF for Intratumoral CD8<sup>+</sup> T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity in another window
Includes: Supplementary data
Journal Articles

Abstract A104: T cell-mediated immune surveillance is inhibited by tumor-intrinsic signaling

Stefani Spranger, Thomas F. Gajewski
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11_Supplement): A104.
https://doi.org/10.1158/2326-6066.IMM2016-A104
Published: 31 October 2016
View article titled, Abstract A104: T cell-mediated immune surveillance is inhibited by tumor-intrinsic signaling
Journal Articles

Molecular Drivers of the Non–T-cell-Inflamed Tumor Microenvironment in Urothelial Bladder Cancer

Randy F. Sweis, Stefani Spranger, Riyue Bao, Gladell P. Paner, Walter M. Stadler, Gary Steinberg, Thomas F. Gajewski
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (7): 563–568.
https://doi.org/10.1158/2326-6066.CIR-15-0274
Published: 30 June 2016
View article titled, Molecular Drivers of the Non–T-cell-Inflamed Tumor Microenvironment in Urothelial Bladder Cancer
Open the PDF for Molecular Drivers of the Non–T-cell-Inflamed Tumor Microenvironment in Urothelial Bladder Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract B154: Immune surveillance is thwarted by tumor-cell intrinsic β-catenin signaling

Stefani Spranger, Brendan Horton, Thomas F. Gajewski
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): B154.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-B154
Published: 03 January 2016
View article titled, Abstract B154: Immune surveillance is thwarted by tumor-cell intrinsic β-catenin signaling