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Scott J. Rodig
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Journal Articles

First-in-Human Clinical Trial of Vaccination with WDVAX, a Dendritic Cell Activating Scaffold Incorporating Autologous Tumor Cell Lysate, in Metastatic Melanoma Patients

F. Stephen Hodi, Anita Giobbie-Hurder, Kwasi Adu-Berchie, Srin Ranasinghe, Ana Lako, Mariano Severgnini, Emily M. Thrash, Jason L. Weirather, Joanna Baginska, Michael P. Manos, Edward J. Doherty, Alexander Stafford, Heather Daley, Jerome Ritz, Patrick A. Ott, Kathleen L. Pfaff, Scott J. Rodig, Charles H. Yoon, Glenn Dranoff, David J. Mooney
Journal: Cancer Immunology Research
Cancer Immunol Res (2025)
https://doi.org/10.1158/2326-6066.CIR-24-0333
Published: 11 April 2025
View articletitled, First-in-Human Clinical Trial of Vaccination with WDVAX, a Dendritic Cell Activating Scaffold Incorporating Autologous Tumor Cell Lysate, in Metastatic Melanoma Patients
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Includes: Supplementary data
Journal Articles

A Phase I Trial of Trebananib, an Angiopoietin 1 and 2 Neutralizing Peptibody, Combined with Pembrolizumab in Patients with Advanced Ovarian and Colorectal Cancer

Brandon M. Huffman, Osama E. Rahma, Kevin Tyan, Yvonne Y. Li, Anita Giobbie-Hurder, Benjamin L. Schlechter, Bruno Bockorny, Michael P. Manos, Andrew D. Cherniack, Joanna Baginska, Adrián Mariño-Enríquez, Katrina Z. Kao, Anna K. Maloney, Allison Ferro, Sarah Kelland, Kimmie Ng, Harshabad Singh, Emma L. Welsh, Kathleen L. Pfaff, Marios Giannakis, Scott J. Rodig, F. Stephen Hodi, James M. Cleary
Journal: Cancer Immunology Research
Cancer Immunol Res (2025) 13 (1): 9–22.
https://doi.org/10.1158/2326-6066.CIR-23-1027
Published: 09 January 2025
View articletitled, A Phase I Trial of Trebananib, an Angiopoietin 1 and 2 Neutralizing Peptibody, Combined with Pembrolizumab in Patients with Advanced Ovarian and Colorectal Cancer
Open the PDF for A Phase I Trial of Trebananib, an Angiopoietin 1 and 2 Neutralizing Peptibody, Combined with Pembrolizumab in Patients with Advanced Ovarian and Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Hippo Signaling Pathway Regulates Cancer Cell–Intrinsic MHC-II Expression

Zexian Zeng, Shengqing Stan Gu, Nofal Ouardaoui, Carly Tymm, Lin Yang, Cheryl J. Wong, Dian Li, Wubing Zhang, Xiaoqing Wang, Jason L. Weirather, Scott J. Rodig, F. Stephen Hodi, Myles Brown, X. Shirley Liu
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (12): 1559–1569.
https://doi.org/10.1158/2326-6066.CIR-22-0227
Published: 02 December 2022
View articletitled, Hippo Signaling Pathway Regulates Cancer Cell–Intrinsic MHC-II Expression
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Includes: Supplementary data
Journal Articles

Abstract A83: Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

Brian C. Miller, Debattama R. Sen, Rose Al Abosy, Kevin Bi, Yamini Virkud, Martin W. LaFleur, Kathleen B. Yates, Ana Lako, Kristen Felt, Girish S. Naik, Michael Manos, Evisa Gjini, Jeffrey J. Ishizuka, F. Stephen Hodi, Scott J. Rodig, Arlene H. Sharpe, W. Nicholas Haining
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (3_Supplement): A83.
https://doi.org/10.1158/2326-6074.TUMIMM19-A83
Published: 02 March 2020
View articletitled, Abstract A83: Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
Journal Articles

Abstract A216: Functionally specialized subsets of exhausted CD8+ T-cells mediate tumor control and response to checkpoint blockade

Debattama R. Sen, Brian C. Miller, Rose Al Abosy, Kevin Bi, Martin W. LaFleur, Kathleen B. Yates, Ana Lako, Kristen D. Felt, Girish S. Naik, Michael Manos, Evisa Gjini, Yamini V. Virkud, Stephen Hodi, Scott J. Rodig, Arlene H. Sharpe, W. Nicholas Haining
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (2_Supplement): A216.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR18-A216
Published: 01 February 2019
View articletitled, Abstract A216: Functionally specialized subsets of exhausted CD8+ T-cells mediate tumor control and response to checkpoint blockade
Journal Articles

Tumor PDCD1LG2 (PD-L2) Expression and the Lymphocytic Reaction to Colorectal Cancer

Yohei Masugi, Reiko Nishihara, Tsuyoshi Hamada, Mingyang Song, Annacarolina da Silva, Keisuke Kosumi, Mancang Gu, Yan Shi, Wanwan Li, Li Liu, Daniel Nevo, Kentaro Inamura, Yin Cao, Xiaoyun Liao, Katsuhiko Nosho, Andrew T. Chan, Marios Giannakis, Adam J. Bass, F. Stephen Hodi, Gordon J. Freeman, Scott J. Rodig, Charles S. Fuchs, Zhi Rong Qian, Jonathan A. Nowak, Shuji Ogino
Journal: Cancer Immunology Research
Cancer Immunol Res (2017) 5 (11): 1046–1055.
https://doi.org/10.1158/2326-6066.CIR-17-0122
Published: 31 October 2017
View articletitled, Tumor PDCD1LG2 (PD-L2) Expression and the Lymphocytic Reaction to Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Cytotoxic T Cells in PD-L1–Positive Malignant Pleural Mesotheliomas Are Counterbalanced by Distinct Immunosuppressive Factors

Mark M. Awad, Robert E. Jones, Hongye Liu, Patrick H. Lizotte, Elena V. Ivanova, Meghana Kulkarni, Grit S. Herter-Sprie, Xiaoyun Liao, Abigail A. Santos, Mark A. Bittinger, Lauren Keogh, Shohei Koyama, Christina Almonte, Jessie M. English, Julianne Barlow, William G. Richards, David A. Barbie, Adam J. Bass, Scott J. Rodig, F. Stephen Hodi, Kai W. Wucherpfennig, Pasi A. Jänne, Lynette M. Sholl, Peter S. Hammerman, Kwok-Kin Wong, Raphael Bueno
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (12): 1038–1048.
https://doi.org/10.1158/2326-6066.CIR-16-0171
Published: 30 November 2016
View articletitled, Cytotoxic T Cells in PD-L1–Positive Malignant Pleural Mesotheliomas Are Counterbalanced by Distinct Immunosuppressive Factors
Open the PDF for Cytotoxic T Cells in PD-L1–Positive Malignant Pleural Mesotheliomas Are Counterbalanced by Distinct Immunosuppressive Factors in another window
Includes: Supplementary data
Journal Articles

Classical Hodgkin Lymphoma with Reduced β2M/MHC Class I Expression Is Associated with Inferior Outcome Independent of 9p24.1 Status

Margaretha G.M. Roemer, Ranjana H. Advani, Robert A. Redd, Geraldine S. Pinkus, Yasodha Natkunam, Azra H. Ligon, Courtney F. Connelly, Christine J. Pak, Christopher D. Carey, Sarah E. Daadi, Bjoern Chapuy, Daphne de Jong, Richard T. Hoppe, Donna S. Neuberg, Margaret A. Shipp, Scott J. Rodig
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11): 910–916.
https://doi.org/10.1158/2326-6066.CIR-16-0201
Published: 31 October 2016
View articletitled, Classical Hodgkin Lymphoma with Reduced β2M/MHC Class I Expression Is Associated with Inferior Outcome Independent of 9p24.1 Status
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Includes: Supplementary data
Journal Articles

Immune Profiling of Adenoid Cystic Carcinoma: PD-L2 Expression and Associations with Tumor-Infiltrating Lymphocytes

Vishwajith Sridharan, Evisa Gjini, Xiaoyun Liao, Nicole G. Chau, Robert I. Haddad, Mariano Severgnini, Peter Hammerman, Adel El-Naggar, Gordon J. Freeman, F. Stephen Hodi, Scott J. Rodig, Glenn Dranoff, Jonathan D. Schoenfeld
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (8): 679–687.
https://doi.org/10.1158/2326-6066.CIR-16-0031
Published: 31 July 2016
View articletitled, Immune Profiling of Adenoid Cystic Carcinoma: PD-L2 Expression and Associations with Tumor-Infiltrating Lymphocytes
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Includes: Supplementary data
Journal Articles

Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model

David A. Reardon, Prafulla C. Gokhale, Sarah R. Klein, Keith L. Ligon, Scott J. Rodig, Shakti H. Ramkissoon, Kristen L. Jones, Amy Saur Conway, Xiaoyun Liao, Jun Zhou, Patrick Y. Wen, Annick D. Van Den Abbeele, F. Stephen Hodi, Lei Qin, Nancy E. Kohl, Arlene H. Sharpe, Glenn Dranoff, Gordon J. Freeman
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (2): 124–135.
https://doi.org/10.1158/2326-6066.CIR-15-0151
Published: 01 February 2016
View articletitled, Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model
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Includes: Supplementary data
Journal Articles

PD-L1 Antibodies to Its Cytoplasmic Domain Most Clearly Delineate Cell Membranes in Immunohistochemical Staining of Tumor Cells

Kathleen M. Mahoney, Heather Sun, Xiaoyun Liao, Ping Hua, Marcella Callea, Edward A. Greenfield, F. Stephen Hodi, Arlene H. Sharpe, Sabina Signoretti, Scott J. Rodig, Gordon J. Freeman
Journal: Cancer Immunology Research
Series: Author Choice
Cancer Immunol Res (2015) 3 (12): 1308–1315.
https://doi.org/10.1158/2326-6066.CIR-15-0116
Published: 06 December 2015
View articletitled, PD-L1 Antibodies to Its Cytoplasmic Domain Most Clearly Delineate Cell Membranes in Immunohistochemical Staining of Tumor Cells
Open the PDF for PD-L1 Antibodies to Its Cytoplasmic Domain Most Clearly Delineate Cell Membranes in Immunohistochemical Staining of Tumor Cells in another window
Includes: Supplementary data
Journal Articles

Epithelial PD-L2 Expression Marks Barrett's Esophagus and Esophageal Adenocarcinoma

Sarah Derks, Katie S. Nason, Xiaoyun Liao, Matthew D. Stachler, Kevin X. Liu, Jie Bin Liu, Ewa Sicinska, Michael S. Goldberg, Gordon J. Freeman, Scott J. Rodig, Jon M. Davison, Adam J. Bass
Journal: Cancer Immunology Research
Series: Author Choice
Cancer Immunol Res (2015) 3 (10): 1123–1129.
https://doi.org/10.1158/2326-6066.CIR-15-0046
Published: 04 October 2015
View articletitled, Epithelial PD-L2 Expression Marks Barrett's Esophagus and Esophageal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation

Eliezer M. Van Allen, Hadrien G. Golay, Yan Liu, Shohei Koyama, Karrie Wong, Amaro Taylor-Weiner, Marios Giannakis, Maegan Harden, Vanesa Rojas-Rudilla, Aaron Chevalier, Tran Thai, Christine Lydon, Stacy Mach, Ada G. Avila, Joshua A. Wong, Alexandra R. Rabin, Joshua Helmkamp, Lynette Sholl, Scott L. Carter, Geoffrey Oxnard, Pasi Janne, Gad Getz, Neal Lindeman, Peter S. Hammerman, Levi A. Garraway, F. Stephen Hodi, Scott J. Rodig, Glenn Dranoff, Kwok-Kin Wong, David A. Barbie
Journal: Cancer Immunology Research
Series: Author Choice
Cancer Immunol Res (2015) 3 (8): 855–863.
https://doi.org/10.1158/2326-6066.CIR-15-0024
Published: 03 August 2015
View articletitled, Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation
Open the PDF for Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation in another window
Includes: Supplementary data