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Pamela S. Ohashi
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Journal Articles

CD103+CD56+ ILCs Are Associated with an Altered CD8+ T-cell Profile within the Tumor Microenvironment

Douglas C. Chung, Noor Shakfa, Jehan Vakharia, Kathrin Warner, Nicolas Jacquelot, Azin Sayad, SeongJun Han, Maryam Ghaedi, Carlos R. Garcia-Batres, Jules Sotty, Arvin Azarmina, Ferris Nowlan, Edward L.Y. Chen, Michael Zon, Alisha R. Elford, Ben X. Wang, Linh T. Nguyen, Miralem Mrkonjic, Blaise A. Clarke, Marcus Q. Bernardini, Benjamin Haibe-Kains, Sarah E. Ferguson, Sarah Q. Crome, Hartland W. Jackson, Pamela S. Ohashi
Journal: Cancer Immunology Research
Cancer Immunol Res (2025) 13 (4): 527–546.
https://doi.org/10.1158/2326-6066.CIR-24-0151
Published: 02 April 2025
View articletitled, CD103+CD56+ ILCs Are Associated with an Altered CD8+ T-cell Profile within the Tumor Microenvironment
Open the PDF for CD103+CD56+ ILCs Are Associated with an Altered CD8+ T-cell Profile within the Tumor Microenvironment in another window
Includes: Supplementary data
Journal Articles

Abstract A009: CD103+CD56+ innate lymphoid cells are associated with an immunosuppressive microenvironment in ovarian cancer

Douglas C Chung, Jehan Vakharia, Kathrin Warner, Nicolas Jacquelot, Azin Sayad, SeongJun Han, Maryam Ghaedi, Carlos R Garcia-Batres, Alisha Elford, Ben X Wang, Linh T Nguyen, Patricia A Shaw, Blaise A Clarke, Marcus Q Bernardini, Sarah E Ferguson, Pamela S Ohashi
Journal: Cancer Immunology Research
Cancer Immunol Res (2023) 11 (12_Supplement): A009.
https://doi.org/10.1158/2326-6074.TUMIMM23-A009
Published: 01 December 2023
View articletitled, Abstract A009: CD103+CD56+ innate lymphoid cells are associated with an immunosuppressive microenvironment in ovarian cancer
Journal Articles

Abstract A047: Tumor specific γδ T cells expand and respond to PD-1 blockade

Scott C. Lien, Dalam Ly, S.Y. Cindy Yang, Ben X. Wang, Michael St. Paul, Ramy Gadalla, Babak Noamani, Sarah Boross-Harmer, Trevor J. Pugh, Anna Spreafico, Naoto Hirano, Albiruni R.A. Razak, Pamela S. Ohashi
Journal: Cancer Immunology Research
Cancer Immunol Res (2023) 11 (12_Supplement): A047.
https://doi.org/10.1158/2326-6074.TUMIMM23-A047
Published: 01 December 2023
View articletitled, Abstract A047: Tumor specific γδ T cells expand and respond to PD-1 blockade
Journal Articles

Abstract B030: Characterizing MAIT cells in lung cancer: Insights from NSCLC and murine models

Stephanie WY Wong, Carolina de Amat Herbozo, Adriana Vukosich-Pennell, Ben X Wang, Pamela S Ohashi, Adrian G Sacher
Journal: Cancer Immunology Research
Cancer Immunol Res (2023) 11 (12_Supplement): B030.
https://doi.org/10.1158/2326-6074.TUMIMM23-B030
Published: 01 December 2023
View articletitled, Abstract B030: Characterizing MAIT cells in lung cancer: Insights from NSCLC and murine models
Journal Articles

Overproduction of IFNγ by Cbl-b–Deficient CD8+ T Cells Provides Resistance against Regulatory T Cells and Induces Potent Antitumor Immunity

SeongJun Han, Zhe Qi Liu, Douglas C. Chung, Michael St. Paul, Carlos R. Garcia-Batres, Azin Sayad, Alisha R. Elford, Matthew J. Gold, Natasha Grimshaw, Pamela S. Ohashi
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (4): 437–452.
https://doi.org/10.1158/2326-6066.CIR-20-0973
Published: 01 April 2022
View articletitled, Overproduction of IFNγ by Cbl-b–Deficient CD8+ T Cells Provides Resistance against Regulatory T Cells and Induces Potent Antitumor Immunity
Open the PDF for Overproduction of IFNγ by Cbl-b–Deficient CD8+ T Cells Provides Resistance against Regulatory T Cells and Induces Potent Antitumor Immunity in another window
Includes: Supplementary data
Journal Articles

Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer

Qingchuan Zhao, Jean-Philippe Laverdure, Joël Lanoix, Chantal Durette, Caroline Côté, Éric Bonneil, Céline M. Laumont, Patrick Gendron, Krystel Vincent, Mathieu Courcelles, Sébastien Lemieux, Douglas G. Millar, Pamela S. Ohashi, Pierre Thibault, Claude Perreault
Journal: Cancer Immunology Research
Series: Author Choice
Cancer Immunol Res (2020) 8 (4): 544–555.
https://doi.org/10.1158/2326-6066.CIR-19-0541
Published: 01 April 2020
View articletitled, Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
Open the PDF for Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function

Michael St. Paul, Samuel D. Saibil, Scott C. Lien, SeongJun Han, Azin Sayad, David T. Mulder, Carlos R. Garcia-Batres, Alisha R. Elford, Kavita Israni-Winger, Céline Robert-Tissot, Michael Zon, Sarah Rachel Katz, Patricia A. Shaw, Blaise A. Clarke, Marcus Q. Bernardini, Linh T. Nguyen, Benjamin Haibe-Kains, Trevor J. Pugh, Pamela S. Ohashi
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (3): 321–333.
https://doi.org/10.1158/2326-6066.CIR-19-0521
Published: 02 March 2020
View articletitled, IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function
Open the PDF for IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function in another window
Includes: Supplementary data
Journal Articles

Zeroing in on Tumor-Reactive TILs

Pamela S. Ohashi
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (9): 719.
https://doi.org/10.1158/2326-6066.CIR-16-0179
Published: 01 September 2016
View articletitled, Zeroing in on Tumor-Reactive TILs
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Journal Articles

B7-H4 Expression by Nonhematopoietic Cells in the Tumor Microenvironment Promotes Antitumor Immunity

Ramtin Rahbar, Albert Lin, Magar Ghazarian, Helen-Loo Yau, Sangeetha Paramathas, Philipp A. Lang, Anita Schildknecht, Alisha R. Elford, Carlos Garcia-Batres, Bernard Martin, Hal K. Berman, Wey L. Leong, David R. McCready, Michael Reedijk, Susan J. Done, Naomi Miller, Bruce Youngson, Woong-Kyung Suh, Tak W. Mak, Pamela S. Ohashi
Journal: Cancer Immunology Research
Series: Author Choice
Cancer Immunol Res (2015) 3 (2): 184–195.
https://doi.org/10.1158/2326-6066.CIR-14-0113
Published: 05 February 2015
View articletitled, B7-H4 Expression by Nonhematopoietic Cells in the Tumor Microenvironment Promotes Antitumor Immunity
Open the PDF for B7-H4 Expression by Nonhematopoietic Cells in the Tumor Microenvironment Promotes Antitumor Immunity in another window
Includes: Supplementary data