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Neal Rosen
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Journal Articles

Intermittent MEK Inhibition with GITR Costimulation Rescues T-cell Function for Increased Efficacy with CTLA-4 Blockade in Solid Tumor Models

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Lauren Dong, Hyejin Choi, Sadna Budhu, Isabell Schulze, Svena Verma, Levi M. Mangarin, Valeria Estrada Nevarro, Nezar Mehanna, Jonathan F. Khan, Divya Venkatesh, Daniel Thach, Neal Rosen, Jedd D. Wolchok, Taha Merghoub
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (10): 1392–1408.
https://doi.org/10.1158/2326-6066.CIR-23-0729
Published: 01 October 2024
View articletitled, Intermittent MEK Inhibition with GITR Costimulation Rescues T-cell Function for Increased Efficacy with CTLA-4 Blockade in Solid Tumor Models
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Includes: Supplementary data
Journal Articles

Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells

Free
Elliott J. Brea, Claire Y. Oh, Eusebio Manchado, Sadna Budhu, Ron S. Gejman, George Mo, Patrizia Mondello, James E. Han, Casey A. Jarvis, David Ulmert, Qing Xiang, Aaron Y. Chang, Ralph J. Garippa, Taha Merghoub, Jedd D. Wolchok, Neal Rosen, Scott W. Lowe, David A. Scheinberg
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11): 936–947.
https://doi.org/10.1158/2326-6066.CIR-16-0177
Published: 31 October 2016
View articletitled, Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells
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Includes: Supplementary data
Journal Articles

Paradoxical Activation of T Cells via Augmented ERK Signaling Mediated by a RAF Inhibitor

Free
Margaret K. Callahan, Gregg Masters, Christine A. Pratilas, Charlotte Ariyan, Jessica Katz, Shigehisa Kitano, Valerie Russell, Ruth Ann Gordon, Shachi Vyas, Jianda Yuan, Ashok Gupta, Jon M. Wigginton, Neal Rosen, Taha Merghoub, Maria Jure-Kunkel, Jedd D. Wolchok
Journal: Cancer Immunology Research
Cancer Immunol Res (2014) 2 (1): 70–79.
https://doi.org/10.1158/2326-6066.CIR-13-0160
Published: 02 January 2014
View articletitled, Paradoxical Activation of T Cells via Augmented ERK Signaling Mediated by a RAF Inhibitor
Open the PDF for Paradoxical Activation of T Cells via Augmented ERK Signaling Mediated by a RAF Inhibitor in another window
Includes: Supplementary data