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Michael Dougan
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Journal Articles

Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor

Paul E. Oberstein, Andressa Dias Costa, Emily A. Kawaler, Victoire Cardot-Ruffino, Osama E. Rahma, Nina Beri, Harshabad Singh, Thomas A. Abrams, Leah H. Biller, James M. Cleary, Peter Enzinger, Brandon M. Huffman, Nadine J. McCleary, Kimberly J. Perez, Douglas A. Rubinson, Benjamin L. Schlechter, Rishi Surana, Matthew B. Yurgelun, S. Jennifer Wang, Joshua Remland, Lauren K. Brais, Naima Bollenrucher, Eugena Chang, Lestat R. Ali, Patrick J. Lenehan, Igor Dolgalev, Gregor Werba, Cibelle Lima, C. Elizabeth Keheler, Keri M. Sullivan, Michael Dougan, Cristina Hajdu, Maya Dajee, Marc R. Pelletier, Saloney Nazeer, Matthew Squires, Dafna Bar-Sagi, Brian M. Wolpin, Jonathan A. Nowak, Diane M. Simeone, Stephanie K. Dougan
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (9): 1221–1235.
https://doi.org/10.1158/2326-6066.CIR-23-1073
Published: 03 September 2024
View article titled, Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor
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Includes: Supplementary data
Journal Articles

Understanding and Overcoming the Inflammatory Toxicities of Immunotherapy

Michael Dougan
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (10): 1230–1235.
https://doi.org/10.1158/2326-6066.CIR-20-0372
Published: 01 October 2020
View article titled, Understanding and Overcoming the Inflammatory Toxicities of Immunotherapy
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Journal Articles

Improved Antitumor Efficacy of Chimeric Antigen Receptor T Cells that Secrete Single-Domain Antibody Fragments

Yushu Joy Xie, Michael Dougan, Jessica R. Ingram, Novalia Pishesha, Tao Fang, Noor Momin, Hidde L. Ploegh
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (4): 518–529.
https://doi.org/10.1158/2326-6066.CIR-19-0734
Published: 01 April 2020
View article titled, Improved Antitumor Efficacy of Chimeric Antigen Receptor T Cells that Secrete Single-Domain Antibody Fragments
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Includes: Supplementary data
Journal Articles

Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1–Specific VHHs

Michael Dougan, Jessica R. Ingram, Hee-Jin Jeong, Munir M. Mosaheb, Patrick T. Bruck, Lestat Ali, Novalia Pishesha, Olga Blomberg, Paul M. Tyler, Mariah M. Servos, Mohammad Rashidian, Quang-De Nguyen, Ulrich H. von Andrian, Hidde L. Ploegh, Stephanie K. Dougan
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (4): 389–401.
https://doi.org/10.1158/2326-6066.CIR-17-0495
Published: 01 April 2018
View article titled, Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1–Specific VHHs
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Includes: Supplementary data
Journal Articles

IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells

Eleanor Clancy-Thompson, Lestat Ali, Patrick T. Bruck, Mark A. Exley, Richard S. Blumberg, Glenn Dranoff, Michael Dougan, Stephanie K. Dougan
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (1): 25–35.
https://doi.org/10.1158/2326-6066.CIR-17-0490
Published: 02 January 2018
View article titled, IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells
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Includes: Supplementary data
Journal Articles

Abstract B18: Noninvasive imaging of antitumor immune responses

Mohammad Rashidian, Michael Dougan, Jessica Ingram, Hidde Ploegh
Journal: Cancer Immunology Research
Cancer Immunol Res (2017) 5 (3_Supplement): B18.
https://doi.org/10.1158/2326-6074.TUMIMM16-B18
Published: 28 February 2017
View article titled, Abstract B18: Noninvasive imaging of antitumor immune responses
Journal Articles

Abstract B112: Targeting immunotherapy to the tumor microenvironment using anti-PDL1 VHH

Michael Dougan, Jessica Ingram, Hidde Ploegh, Stephanie K. Dougan
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11_Supplement): B112.
https://doi.org/10.1158/2326-6066.IMM2016-B112
Published: 31 October 2016
View article titled, Abstract B112: Targeting immunotherapy to the tumor microenvironment using anti-PDL1 VHH
Journal Articles

Abstract B021: Single domain antibodies targeting CTLA-4 demonstrate a critical role for Fc in the antitumor response

Michael Dougan, Jessica Ingram, Olga Blomberg, Mohammad Rashidian, Edmund Keliher, Ralph Weissleder, Steven Almo, Hidde Ploegh
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11_Supplement): B021.
https://doi.org/10.1158/2326-6066.IMM2016-B021
Published: 31 October 2016
View article titled, Abstract B021: Single domain antibodies targeting CTLA-4 demonstrate a critical role for Fc in the antitumor response
Journal Articles

Transnuclear TRP1-Specific CD8 T Cells with High or Low Affinity TCRs Show Equivalent Antitumor Activity

Stephanie K. Dougan, Michael Dougan, Jun Kim, Jacob A. Turner, Souichi Ogata, Hyun-Il Cho, Rudolf Jaenisch, Esteban Celis, Hidde L. Ploegh
Journal: Cancer Immunology Research
Cancer Immunol Res (2013) 1 (2): 99–111.
https://doi.org/10.1158/2326-6066.CIR-13-0047
Published: 07 August 2013
View article titled, Transnuclear TRP1-Specific CD8 T Cells with High or Low Affinity TCRs Show Equivalent Antitumor Activity
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