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Mark J. Smyth
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Journal Articles

NKG7 Is Required for Optimal Antitumor T-cell Immunity

Xian-Yang Li, Dillon Corvino, Bianca Nowlan, Amelia Roman Aguilera, Susanna S. Ng, Matthias Braun, Anthony R. Cillo, Tobias Bald, Mark J. Smyth, Christian R. Engwerda
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (2): 154–161.
https://doi.org/10.1158/2326-6066.CIR-20-0649
Published: 01 February 2022
View article titled, NKG7 Is Required for Optimal Antitumor T-cell Immunity
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Includes: Supplementary data
Journal Articles

ASC Modulates CTL Cytotoxicity and Transplant Outcome Independent of the Inflammasome

Melody Cheong, Kate H. Gartlan, Jason S. Lee, Siok-Keen Tey, Ping Zhang, Rachel D. Kuns, Christopher E. Andoniou, Jose Paulo Martins, Karshing Chang, Vivien R. Sutton, Greg Kelly, Antiopi Varelias, Slavica Vuckovic, Kate A. Markey, Glen M. Boyle, Mark J. Smyth, Christian R. Engwerda, Kelli P.A. MacDonald, Joseph A. Trapani, Mariapia A. Degli-Esposti, Motoko Koyama, Geoffrey R. Hill
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (8): 1085–1098.
https://doi.org/10.1158/2326-6066.CIR-19-0653
Published: 03 August 2020
View article titled, ASC Modulates CTL Cytotoxicity and Transplant Outcome Independent of the Inflammasome
Open the PDF for ASC Modulates CTL Cytotoxicity and Transplant Outcome Independent of the Inflammasome in another window
Includes: Supplementary data
Journal Articles

Control of Metastases via Myeloid CD39 and NK Cell Effector Function

Juming Yan, Xian-Yang Li, Amelia Roman Aguilera, Christos Xiao, Celia Jacoberger-Foissac, Bianca Nowlan, Simon C. Robson, Courtney Beers, Achim K. Moesta, Nishamol Geetha, Michele W.L. Teng, Mark J. Smyth
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (3): 356–367.
https://doi.org/10.1158/2326-6066.CIR-19-0749
Published: 02 March 2020
View article titled, Control of Metastases via Myeloid CD39 and NK Cell Effector Function
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Includes: Supplementary data
Journal Articles

CD96 Is an Immune Checkpoint That Regulates CD8+ T-cell Antitumor Function

Deepak Mittal, Ailin Lepletier, Jason Madore, Amelia Roman Aguilera, Kimberley Stannard, Stephen J. Blake, Vicki L.J. Whitehall, Cheng Liu, Mark L. Bettington, Kazuyoshi Takeda, Georgina V. Long, Richard A. Scolyer, Ruth Lan, Nathan Siemers, Alan Korman, Michele W.L. Teng, Robert J. Johnston, William C. Dougall, Mark J. Smyth
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (4): 559–571.
https://doi.org/10.1158/2326-6066.CIR-18-0637
Published: 01 April 2019
View article titled, CD96 Is an Immune Checkpoint That Regulates CD8<sup>+</sup> T-cell Antitumor Function
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Includes: Supplementary data
Journal Articles

Abstract PR02: Neoadjuvant immunotherapy pre-cancer surgery relieves tumor-specific CD8+ T-cell dysfunction and restores memory differentiation potential

Jake S. O'Donnell, Jing Liu, Stacey Allen, Scott Mueller, Mark J. Smyth, Michele W.L. Teng
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (2_Supplement): PR02.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR18-PR02
Published: 01 February 2019
View article titled, Abstract PR02: Neoadjuvant immunotherapy pre-cancer surgery relieves tumor-specific CD8+ T-cell dysfunction and restores memory differentiation potential
Journal Articles

Experimental Lung Metastases in Mice Are More Effectively Inhibited by Blockade of IL23R than IL23

Juming Yan, Stacey Allen, Dipti Vijayan, Xian-Yang Li, Heidi Harjunpää, Kazuyoshi Takeda, Jing Liu, Daniel J. Cua, Mark J. Smyth, Michele W.L. Teng
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (8): 978–987.
https://doi.org/10.1158/2326-6066.CIR-18-0011
Published: 31 July 2018
View article titled, Experimental Lung Metastases in Mice Are More Effectively Inhibited by Blockade of IL23R than IL23
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Includes: Supplementary data
Journal Articles

Interleukin-12 from CD103+ Batf3-Dependent Dendritic Cells Required for NK-Cell Suppression of Metastasis

Deepak Mittal, Dipti Vijayan, Eva M. Putz, Amelia R. Aguilera, Kate A. Markey, Jasmin Straube, Stephen Kazakoff, Stephen L. Nutt, Kazuyoshi Takeda, Geoffrey R. Hill, Nicola Waddell, Mark J. Smyth
Journal: Cancer Immunology Research
Cancer Immunol Res (2017) 5 (12): 1098–1108.
https://doi.org/10.1158/2326-6066.CIR-17-0341
Published: 30 November 2017
View article titled, Interleukin-12 from CD103<sup>+</sup> Batf3-Dependent Dendritic Cells Required for NK-Cell Suppression of Metastasis
Open the PDF for Interleukin-12 from CD103<sup>+</sup> Batf3-Dependent Dendritic Cells Required for NK-Cell Suppression of Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract PR07: Use of a novel mouse model to investigate immune related adverse events arising from immunotherapies

Stephen J. Blake, Jing Liu, Harjunpaa Heidi, Mark J. Smyth, Michele W.L. Teng
Journal: Cancer Immunology Research
Cancer Immunol Res (2017) 5 (3_Supplement): PR07.
https://doi.org/10.1158/2326-6074.TUMIMM16-PR07
Published: 28 February 2017
View article titled, Abstract PR07: Use of a novel mouse model to investigate immune related adverse events arising from immunotherapies
Journal Articles

Abstract IA27: Novel natural killer cell targets for cancer immunotherapy

Mark J. Smyth, Eva Putz, Stephen Blake, Aaron Gao, Fernando Guimaraes, John Miles, Bill Dougall, Michele WL Teng, Nicholas D. Huntington
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11_Supplement): IA27.
https://doi.org/10.1158/2326-6066.IMM2016-IA27
Published: 31 October 2016
View article titled, Abstract IA27: Novel natural killer cell targets for cancer immunotherapy
Journal Articles

Abstract B115: Improved efficacy of neoadjuvant compared to adjuvant immunotherapy to eradicate metastatic disease

Jing Liu, Stephen Blake, Michelle Yong, Heidi Harjunpaa, Shin Foong Ngiow, Kazuyoshi Takeda, Arabella Young, Stacey Allen, Mark J. Smyth, Michele WL Teng
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11_Supplement): B115.
https://doi.org/10.1158/2326-6066.IMM2016-B115
Published: 31 October 2016
View article titled, Abstract B115: Improved efficacy of neoadjuvant compared to adjuvant immunotherapy to eradicate metastatic disease
Journal Articles

Abstract B155: Anti-CD137 mAb therapy of multiple myeloma

Camille Guillerey, Lucas Ferrari de Andrade, Slavica Vuckovic, David Ritchie, Marta Chesi, Leif Bergsagel, Geoffrey R. Hill, Ludovic Martinet, Mark J. Smyth
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): B155.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-B155
Published: 03 January 2016
View article titled, Abstract B155: Anti-CD137 mAb therapy of multiple myeloma
Journal Articles

Abstract B122: A preclinical mouse model to assess antitumor efficacy and development of immune related adverse events (irAEs) following combination immunotherapies

Jing Liu, Stephten J. Blake, Kirsten A. Fairfax, Michelle C.R. Yong, Stacey Allen, Mark J. Smyth, Michele W.L. Teng
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): B122.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-B122
Published: 03 January 2016
View article titled, Abstract B122: A preclinical mouse model to assess antitumor efficacy and development of immune related adverse events (irAEs) following combination immunotherapies