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Marc R. Pelletier
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Journal Articles

Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor

Open Access
Paul E. Oberstein, Andressa Dias Costa, Emily A. Kawaler, Victoire Cardot-Ruffino, Osama E. Rahma, Nina Beri, Harshabad Singh, Thomas A. Abrams, Leah H. Biller, James M. Cleary, Peter Enzinger, Brandon M. Huffman, Nadine J. McCleary, Kimberly J. Perez, Douglas A. Rubinson, Benjamin L. Schlechter, Rishi Surana, Matthew B. Yurgelun, S. Jennifer Wang, Joshua Remland, Lauren K. Brais, Naima Bollenrucher, Eugena Chang, Lestat R. Ali, Patrick J. Lenehan, Igor Dolgalev, Gregor Werba, Cibelle Lima, C. Elizabeth Keheler, Keri M. Sullivan, Michael Dougan, Cristina Hajdu, Maya Dajee, Marc R. Pelletier, Saloney Nazeer, Matthew Squires, Dafna Bar-Sagi, Brian M. Wolpin, Jonathan A. Nowak, Diane M. Simeone, Stephanie K. Dougan
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (9): 1221–1235.
https://doi.org/10.1158/2326-6066.CIR-23-1073
Published: 03 September 2024
View articletitled, Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor
Open the PDF for Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor in another window
Includes: Supplementary data
Journal Articles

Targeting the IL1β Pathway for Cancer Immunotherapy Remodels the Tumor Microenvironment and Enhances Antitumor Immune Responses

Available to Purchase
Rohan Diwanji, Neil A. O'Brien, Jiyoung E. Choi, Beverly Nguyen, Tyler Laszewski, Angelo L. Grauel, Zheng Yan, Xin Xu, Jincheng Wu, David A. Ruddy, Michelle Piquet, Marc R. Pelletier, Alexander Savchenko, LaSalette Charette, Vanessa Rodrik-Outmezguine, Jason Baum, John M. Millholland, Connie C. Wong, Anne-Marie Martin, Glenn Dranoff, Iulian Pruteanu-Malinici, Viviana Cremasco, Catherine Sabatos-Peyton, Pushpa Jayaraman
Journal: Cancer Immunology Research
Cancer Immunol Res (2023) 11 (6): 777–791.
https://doi.org/10.1158/2326-6066.CIR-22-0290
Published: 02 June 2023
View articletitled, Targeting the IL1β Pathway for Cancer Immunotherapy Remodels the Tumor Microenvironment and Enhances Antitumor Immune Responses
Open the PDF for Targeting the IL1β Pathway for Cancer Immunotherapy Remodels the Tumor Microenvironment and Enhances Antitumor Immune Responses in another window
Includes: Supplementary data
Journal Articles

Preclinical Characterization and Phase I Study of an Anti–HER2-TLR7 Immune-Stimulator Antibody Conjugate in Patients with HER2+ Malignancies

Free
Filip Janku, Sae-Won Han, Toshihiko Doi, Alessio Amatu, Jaffer A. Ajani, Yasutoshi Kuboki, Alex Cortez, Susan E. Cellitti, Ping C. Mahling, Kulandayan Subramanian, Heidi A. Schoenfeld, Sarah M. Choi, Lori A. Iaconis, Lang Ho Lee, Marc R. Pelletier, Glenn Dranoff, Vasileios Askoxylakis, Salvatore Siena
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (12): 1441–1461.
https://doi.org/10.1158/2326-6066.CIR-21-0722
Published: 02 December 2022
View articletitled, Preclinical Characterization and Phase I Study of an Anti–HER2-TLR7 Immune-Stimulator Antibody Conjugate in Patients with HER2+ Malignancies
Open the PDF for Preclinical Characterization and Phase I Study of an Anti–HER2-TLR7 Immune-Stimulator Antibody Conjugate in Patients with HER2+ Malignancies in another window
Includes: Supplementary data