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Lynn M. Schuchter
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Journal Articles

Anti–CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control

Emilio Sanseviero, Erin M. O’Brien, Jenna R. Karras, Tamer B. Shabaneh, Bulent Arman Aksoy, Wei Xu, Cathy Zheng, Xiangfan Yin, Xiaowei Xu, Giorgos C. Karakousis, Ravi K. Amaravadi, Brian Nam, Mary Jo Turk, Jeff Hammerbacher, Mark P. Rubinstein, Lynn M. Schuchter, Tara C. Mitchell, Qin Liu, Erica L. Stone
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (8): 1371–1380.
https://doi.org/10.1158/2326-6066.CIR-18-0386
Published: 01 August 2019
View article titled, Anti–CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control
Open the PDF for Anti–CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control in another window
Includes: Supplementary data
Journal Articles

Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer

Julia Tchou, Yangbing Zhao, Bruce L. Levine, Paul J Zhang, Megan M. Davis, Jan Joseph Melenhorst, Irina Kulikovskaya, Andrea L Brennan, Xiaojun Liu, Simon F. Lacey, Avery D. Posey, Jr., Austin D. Williams, Alycia So, Jose R. Conejo-Garcia, Gabriela Plesa, Regina M. Young, Shannon McGettigan, Jean Campbell, Robert H. Pierce, Jennifer M. Matro, Angela M. DeMichele, Amy S. Clark, Laurence J. Cooper, Lynn M. Schuchter, Robert H. Vonderheide, Carl H. June
Journal: Cancer Immunology Research
Series: Author Choice
Cancer Immunol Res (2017) 5 (12): 1152–1161.
https://doi.org/10.1158/2326-6066.CIR-17-0189
Published: 30 November 2017
View article titled, Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer
Open the PDF for Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PR05: Peripheral blood immune profiling of anti-PD-1 therapy in human melanoma reveals a link between T cell re-invigoration and tumor burden that predicts response

Alexander Huang, Michael A. Postow, Robert J. Orlowski, Rosemarie Mick, Bertram Bengsch, Sasi Manne, Wei Xu, Shannon Harmon, Matthew Adamow, Deborah Kuk, Katherine Panangeas, Cristina Carerra, Phillip Wong, Felix Quagliarello, Kristen E. Pauken, Ramin S. Herati, Suzanne McGettigan, Shawn Kothari, Sangeeth M. George, Brandon Wenz, Kurt D'Andrea, Xiaowei Xu, Ravi K. Amaravadi, Giorgos Karakousis, Lynn M. Schuchter, Katherine L. Nathanson, Jedd D. Wolchok, Tara C. Gangadhar, John Wherry
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (11_Supplement): PR05.
https://doi.org/10.1158/2326-6066.IMM2016-PR05
Published: 31 October 2016
View article titled, Abstract PR05: Peripheral blood immune profiling of anti-PD-1 therapy in human melanoma reveals a link between T cell re-invigoration and tumor burden that predicts response
Journal Articles

Abstract A38: Phase I study of combination immunotherapy with agonistic CD40 monoclonal antibody (mAb) CP-870,893 (αCD40) and anti-CTLA-4 antibody tremelimumab (treme) in patients with metastatic melanoma

David L. Bajor, Rosemarie Mick, Matthew J. Riese, Richman P. Lee, Xiaowei Xu, Drew A. Torigian, Erietta Stelekati, Martha Sweeney, Brendan J. Sullivan, Lynn M. Schuchter, Ravi Amaravadi, E John Wherry, Robert H. Vonderheide
Journal: Cancer Immunology Research
Cancer Immunol Res (2015) 3 (10_Supplement): A38.
https://doi.org/10.1158/2326-6074.TUMIMM14-A38
Published: 09 October 2015
View article titled, Abstract A38: Phase I study of combination immunotherapy with agonistic CD40 monoclonal antibody (mAb) CP-870,893 (αCD40) and anti-CTLA-4 antibody tremelimumab (treme) in patients with metastatic melanoma
Journal Articles

Immune Activation and a 9-Year Ongoing Complete Remission Following CD40 Antibody Therapy and Metastasectomy in a Patient with Metastatic Melanoma

David L. Bajor, Xiaowei Xu, Drew A. Torigian, Rosemarie Mick, Laura R. Garcia, Lee P. Richman, Cindy Desmarais, Katherine L. Nathanson, Lynn M. Schuchter, Michael Kalos, Robert H. Vonderheide
Journal: Cancer Immunology Research
Cancer Immunol Res (2014) 2 (11): 1051–1058.
https://doi.org/10.1158/2326-6066.CIR-14-0154
Published: 02 November 2014
View article titled, Immune Activation and a 9-Year Ongoing Complete Remission Following CD40 Antibody Therapy and Metastasectomy in a Patient with Metastatic Melanoma
Open the PDF for Immune Activation and a 9-Year Ongoing Complete Remission Following CD40 Antibody Therapy and Metastasectomy in a Patient with Metastatic Melanoma in another window