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Jun Gui
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Journal Articles

In Situ Delivery of Gasdermin E mRNA Promotes Antitumor Immunity via Creatine-Elicited Type I Interferon Signaling in Monocytes

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Hanjun Li, Jing Lu, Shudan Tan, Ting Jiang, Xin He, Wen Qiao, Cegui Hu, Sumiya Dalangood, Jinzhong Lin, Jun Gui
Journal: Cancer Immunology Research
Cancer Immunol Res (2025) 13 (6): 939–956.
https://doi.org/10.1158/2326-6066.CIR-24-0834
Published: 04 June 2025
View articletitled, In Situ Delivery of Gasdermin E mRNA Promotes Antitumor Immunity via Creatine-Elicited Type I Interferon Signaling in Monocytes
Open the PDF for In Situ Delivery of Gasdermin E mRNA Promotes Antitumor Immunity via Creatine-Elicited Type I Interferon Signaling in Monocytes in another window
Includes: Supplementary data
Journal Articles

Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment

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Hongru Zhang, Vivek S. Tomar, Jinyang Li, Raghavendra Basavaraja, Fangxue Yan, Jun Gui, Noreen McBrearty, Tara Lee Costich, Daniel P. Beiting, M. Andres Blanco, Jose R. Conejo-Garcia, Gurpanna Saggu, Allison Berger, Yulia Nefedova, Dmitry I. Gabrilovich, Serge Y. Fuchs
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (12): 1490–1505.
https://doi.org/10.1158/2326-6066.CIR-22-0295
Published: 02 December 2022
View articletitled, Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment
Open the PDF for Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment in another window
Includes: Supplementary data
Journal Articles

Abstract A100: Downregulation of type 1 interferon receptor (IFNAR1) regulates the balance of regulatory T cells (Tregs) and cytotoxic T lymphocytes (CTLs) in tumor microenvironment

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Hongru Zhang, Jun Gui, Angelica Ortiz, Serge Fuchs
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (3_Supplement): A100.
https://doi.org/10.1158/2326-6074.TUMIMM19-A100
Published: 02 March 2020
View articletitled, Abstract A100: Downregulation of type 1 interferon receptor (IFNAR1) regulates the balance of regulatory T cells (Tregs) and cytotoxic T lymphocytes (CTLs) in tumor microenvironment