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Ira Mellman
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Journal Articles

Different PD-L1 Assays Reveal Distinct Immunobiology and Clinical Outcomes in Urothelial Cancer

Open Access
Matthew D. Galsky, Mark Kockx, Juliette Roels, Roos Van Elzen, Xiangnan Guan, Kobe Yuen, Deepali Rishipathak, Jonathan F. Anker, Sacha Gnjatic, Sudeh Izadmehr, Shomyseh Sanjabi, Robert J. Johnston, Maureen Peterson, Hartmut Koeppen, Justin M. David, Saurabh Gupta, Aristotelis Bamias, Jose Angel Arranz, Eiji Kikuchi, Maria De Santis, Ian D. Davis, Patrick Williams, Sandrine Bernhard, Ira Mellman, Enrique Grande, Romain Banchereau, Sanjeev Mariathasan
Journal: Cancer Immunology Research
Cancer Immunol Res (2025) 13 (4): 476–486.
https://doi.org/10.1158/2326-6066.CIR-24-0649
Published: 02 April 2025
View articletitled, Different PD-L1 Assays Reveal Distinct Immunobiology and Clinical Outcomes in Urothelial Cancer
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Includes: Supplementary data
Journal Articles

Abstract PR-06: Personalized RNA neoantigen vaccines induce long-lived CD8+ T effector cells in pancreatic cancer

Free
Pablo Guasp, Zachary Sethna, Charlotte Reiche, Martina Milighetti, Nicholas Ceglia, Erin Patterson, Nan Pang, George Payne, Ohmoto Akihiro, Luis A Rojas, Masataka Amisaki, Abderezak Zebboudj, Emmanuel Bruno, Linsey Zhang, Zagaa Odgerel, Charlotte Cheng, Evelyna Derhovanessian, Luisa Manning, Felicitas Müller, Ina Rhee, Mahesh Yadav, Mithat Gönen, Olca Basturk, Andre S Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M Varghese, Elizabeth Won, Avni Desai, Alice C Wei, Michael I D'Angelica, Peter Kingham, Kevin C Soares, William R Jarnagin, Jeffrey Drevin, Eileen M O'Reilly, Ira Mellman, Ugur Sahin, Özlem Türeci, Benjamin D Greenbaum, Vinod P Balachandran
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (10_Supplement): PR-06.
https://doi.org/10.1158/2326-6074.TUMIMM24-PR-06
Published: 18 October 2024
View articletitled, Abstract PR-06: Personalized RNA neoantigen vaccines induce long-lived CD8+ T effector cells in pancreatic cancer
Journal Articles

Abstract A030: CD4 neoantigen mRNA vaccine enhances endogenous CD8 responses and tumor control

Free
Camille-Charlotte Balanca, Aude-Hélène Capietto, Catherine Carbone, Alan Gutierrez, Yajun Chestnut, Ellen Duong, Aditya Anand, Anthony Antonelli, Jeanne Cheung, Shiuh Luoh, Ariane Nissembaum, Keiko Hokeness, Sara Wichner, Emily Freund, Vincent Javinal, Romain Bouziat, Joshua Gober, Adel ElSohly, Jon Linehan, Ugur Sahin, Lélia Delamarre, Ira Mellman
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (10_Supplement): A030.
https://doi.org/10.1158/2326-6074.TUMIMM24-A030
Published: 18 October 2024
View articletitled, Abstract A030: CD4 neoantigen mRNA vaccine enhances endogenous CD8 responses and tumor control
Journal Articles

Abstract A043: Costimulation by type 1 dendritic cells facilitates the differentiation of non-exhausted anti-tumor T cells

Free
Ellen Duong, Karl Banta, Katie Nutsch, Thomas Wu, Eugene Chiang, Ira Mellman
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (10_Supplement): A043.
https://doi.org/10.1158/2326-6074.TUMIMM24-A043
Published: 18 October 2024
View articletitled, Abstract A043: Costimulation by type 1 dendritic cells facilitates the differentiation of non-exhausted anti-tumor T cells
Journal Articles

The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity

Open Access
Junghyun Lim, Ryan Rodriguez, Katherine Williams, John Silva, Alan G. Gutierrez, Paul Tyler, Faezzah Baharom, Tao Sun, Eva Lin, Scott Martin, Brandon D. Kayser, Robert J. Johnston, Ira Mellman, Lélia Delamarre, Nathaniel R. West, Sören Müller, Yan Qu, Klaus Heger
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (6): 663–672.
https://doi.org/10.1158/2326-6066.CIR-23-1078
Published: 04 June 2024
View articletitled, The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity
Open the PDF for The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity in another window
Includes: Supplementary data
Journal Articles

Coming of Age: Human Genomics and the Cancer–Immune Set Point

Open Access
Christian Hammer, Ira Mellman
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (6): 674–679.
https://doi.org/10.1158/2326-6066.CIR-21-1017
Published: 03 June 2022
View articletitled, Coming of Age: Human Genomics and the Cancer–Immune Set Point
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Journal Articles

Abstract PO084: Patterns of T cell clonal expansion in cancer patients associate with response to immunotherapy

Free
Shravan Madireddi, Thomas D. Wu, Patricia E. de Almeida, Romain Banchereau, Ying-Jiun J. Chen, Avantika S. Chitre, Hina Iftikhar, William E. O'Gorman, Amelia Au-Yeung, Chikara Takahashi, Leonard D. Goldstein, Chungkee Poon, Shilpa Keerthivasan, Sanjeev Mariathasan, Meghna Das Thakur, Mahrukh A. Huseni, Marcus Ballinger, Ivette Estay, Patrick Caplazi, Zora Modrusan, Lélia Delamarre, Ira Mellman, Richard Bourgon, Jane L. Grogan
Journal: Cancer Immunology Research
Cancer Immunol Res (2021) 9 (2_Supplement): PO084.
https://doi.org/10.1158/2326-6074.TUMIMM20-PO084
Published: 03 February 2021
View articletitled, Abstract PO084: Patterns of T cell clonal expansion in cancer patients associate with response to immunotherapy
Journal Articles

Abstract IA18: The mechanistic basis of cancer immunotherapy

Free
Ira Mellman
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (4_Supplement): IA18.
https://doi.org/10.1158/2326-6074.TUMIMM18-IA18
Published: 01 April 2020
View articletitled, Abstract IA18: The mechanistic basis of cancer immunotherapy
Journal Articles

Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models

Available to Purchase
Huizhong Xiong, Stephanie Mittman, Ryan Rodriguez, Patricia Pacheco-Sanchez, Marina Moskalenko, Yagai Yang, Justin Elstrott, Alex T. Ritter, Sören Müller, Dorothee Nickles, Teresita L. Arenzana, Aude-Hélène Capietto, Lélia Delamarre, Zora Modrusan, Sascha Rutz, Ira Mellman, Rafael Cubas
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (6): 963–976.
https://doi.org/10.1158/2326-6066.CIR-18-0750
Published: 03 June 2019
View articletitled, Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models
Open the PDF for Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models in another window
Includes: Multimedia, Supplementary data
Journal Articles

De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute

Available to Purchase
Ira Mellman, Vanessa M. Hubbard-Lucey, Matthew J. Tontonoz, Michael D. Kalos, Daniel S. Chen, James P. Allison, Charles G. Drake, Hy Levitsky, Nils Lonberg, Sjoerd H. van der Burg, Douglas T. Fearon, E. John Wherry, Israel Lowy, Robert H. Vonderheide, Patrick Hwu
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (4): 279–288.
https://doi.org/10.1158/2326-6066.CIR-16-0045
Published: 31 March 2016
View articletitled, De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute
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Journal Articles

Dendritic Cells: Master Regulators of the Immune Response

Available to Purchase
Ira Mellman
Journal: Cancer Immunology Research
Cancer Immunol Res (2013) 1 (3): 145–149.
https://doi.org/10.1158/2326-6066.CIR-13-0102
Published: 08 September 2013
View articletitled, Dendritic Cells: Master Regulators of the Immune Response
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