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Hiroyoshi Nishikawa
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Journal Articles

The HSP90 Inhibitor Pimitespib Targets Regulatory T Cells in the Tumor Microenvironment

Ayaka Tsuge, Sho Watanabe, Akihito Kawazoe, Yosuke Togashi, Kota Itahashi, Mari Masuda, Atsuo Sai, Shogo Takei, Hiromi Muraoka, Shuichi Ohkubo, Daisuke Sugiyama, Yue Yan, Shota Fukuoka, Toshihiko Doi, Kohei Shitara, Shohei Koyama, Hiroyoshi Nishikawa
Journal: Cancer Immunology Research
Cancer Immunol Res (2025) 13 (2): 273–285.
https://doi.org/10.1158/2326-6066.CIR-24-0713
Published: 03 February 2025
View article titled, The HSP90 Inhibitor Pimitespib Targets Regulatory T Cells in the Tumor Microenvironment
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Includes: Supplementary data
Journal Articles

Hiroshi Shiku, MD, PhD: In Memoriam (1943–2022)

Hiroyoshi Nishikawa, Alexander Knuth, Ryuzo Ueda
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (11): 1289–1290.
https://doi.org/10.1158/2326-6066.CIR-22-0758
Published: 02 November 2022
View article titled, Hiroshi Shiku, MD, PhD: In Memoriam (1943–2022)
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Journal Articles

Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis

Kiyomi Shitaoka, Hiroshi Hamana, Hiroyuki Kishi, Yoshihiro Hayakawa, Eiji Kobayashi, Kenta Sukegawa, Xiuhong Piao, Fulian Lyu, Takuya Nagata, Daisuke Sugiyama, Hiroyoshi Nishikawa, Atsushi Tanemura, Ichiro Katayama, Mutsunori Murahashi, Yasushi Takamatsu, Kenzaburo Tani, Tatsuhiko Ozawa, Atsushi Muraguchi
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (4): 378–388.
https://doi.org/10.1158/2326-6066.CIR-17-0489
Published: 01 April 2018
View article titled, Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis
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Includes: Supplementary data
Journal Articles

Effector Regulatory T Cells Reflect the Equilibrium between Antitumor Immunity and Autoimmunity in Adult T-cell Leukemia

Hiroshi Ureshino, Takero Shindo, Hiroyoshi Nishikawa, Nobukazu Watanabe, Eri Watanabe, Natsuko Satoh, Kazutaka Kitaura, Hiroaki Kitamura, Kazuko Doi, Kotaro Nagase, Hiromi Kimura, Makoto Samukawa, Susumu Kusunoki, Masaharu Miyahara, Tadasu Shin-I, Ryuji Suzuki, Shimon Sakaguchi, Shinya Kimura
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (8): 644–649.
https://doi.org/10.1158/2326-6066.CIR-15-0303
Published: 31 July 2016
View article titled, Effector Regulatory T Cells Reflect the Equilibrium between Antitumor Immunity and Autoimmunity in Adult T-cell Leukemia
Open the PDF for Effector Regulatory T Cells Reflect the Equilibrium between Antitumor Immunity and Autoimmunity in Adult T-cell Leukemia in another window
Includes: Supplementary data
Journal Articles

Hypomethylation of the Treg-Specific Demethylated Region in FOXP3 Is a Hallmark of the Regulatory T-cell Subtype in Adult T-cell Leukemia

Yayoi Shimazu, Yutaka Shimazu, Masakatsu Hishizawa, Masahide Hamaguchi, Yuya Nagai, Noriko Sugino, Sumie Fujii, Masahiro Kawahara, Norimitsu Kadowaki, Hiroyoshi Nishikawa, Shimon Sakaguchi, Akifumi Takaori-Kondo
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (2): 136–145.
https://doi.org/10.1158/2326-6066.CIR-15-0148
Published: 01 February 2016
View article titled, Hypomethylation of the Treg-Specific Demethylated Region in <em>FOXP3</em> Is a Hallmark of the Regulatory T-cell Subtype in Adult T-cell Leukemia
Open the PDF for Hypomethylation of the Treg-Specific Demethylated Region in <em>FOXP3</em> Is a Hallmark of the Regulatory T-cell Subtype in Adult T-cell Leukemia in another window
Includes: Supplementary data
Journal Articles

Abstract B035: Self-tumor-antigen-specific CD8 T cells were suppressed by regulatory T cells

Yuka Maeda, Hiroyoshi Nishikawa, Shimon Sakaguchi
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): B035.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-B035
Published: 03 January 2016
View article titled, Abstract B035: Self-tumor-antigen-specific CD8 T cells were suppressed by regulatory T cells
Journal Articles

Abstract B174: FOXP3+CD4+ T-cell subpopulations distinctly control the prognosis of colorectal cancers

Takuro Saito, Hiroyoshi Nishikawa, Hisashi Wada, Masaki Mori, Yuichiro Doki, Shimon Sakaguchi
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): B174.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-B174
Published: 03 January 2016
View article titled, Abstract B174: FOXP3+CD4+ T-cell subpopulations distinctly control the prognosis of colorectal cancers
Journal Articles

Abstract A033: Phase Ia study of FoxP3+ CD4 Treg depletion by infusion of a humanized anti-CCR4 antibody, KW-0761, in cancer patients

Koji Kurose, Yoshihiro Ohue, Hisashi Wada, Toshihiko Doi, Hiroyoshi Nishikawa, Mikio Oka, Ryuzo Ueda
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): A033.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-A033
Published: 03 January 2016
View article titled, Abstract A033: Phase Ia study of FoxP3+ CD4 Treg depletion by infusion of a humanized anti-CCR4 antibody, KW-0761, in cancer patients