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Eliezer M. Van Allen
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Journal Articles

Randomized Phase II Study Evaluating the Addition of Pembrolizumab to Radium-223 in Metastatic Castration-resistant Prostate Cancer

Atish D. Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire, Jaqueline Marquez, David D. Yang, Abhishek Tripathi, Jacqueline M. Kilar, Meredith Flynn, Brianna Maynard, Rebecca Reichel, Amanda F. Pace, Brandon K. Chen, Eliezer M. Van Allen, Kerry Kilbridge, Xiao X. Wei, Bradley A. McGregor, Mark M. Pomerantz, Rupal S. Bhatt, Christopher J. Sweeney, Glenn J. Bubley, Heather A. Jacene, Mary-Ellen Taplin, Franklin W. Huang, Lauren C. Harshman, Lawrence Fong
Journal: Cancer Immunology Research
Cancer Immunol Res (2024) 12 (6): 704–718.
https://doi.org/10.1158/2326-6066.CIR-22-0306
Published: 04 June 2024
View article titled, Randomized Phase II Study Evaluating the Addition of Pembrolizumab to Radium-223 in Metastatic Castration-resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Circulating and Intratumoral Immune Determinants of Response to Atezolizumab plus Bevacizumab in Patients with Variant Histology or Sarcomatoid Renal Cell Carcinoma

Renee Maria Saliby, Talal El Zarif, Ziad Bakouny, Valisha Shah, Wanling Xie, Ronan Flippot, Thomas Denize, M. Harry Kane, Katrine N. Madsen, Miriam Ficial, Laure Hirsch, Xiao X. Wei, John A. Steinharter, Lauren C. Harshman, Ulka N. Vaishampayan, Mariano Severgnini, David F. McDermott, Gwo-Shu Mary Lee, Wenxin Xu, Eliezer M. Van Allen, Bradley A. McGregor, Sabina Signoretti, Toni K. Choueiri, Rana R. McKay, David A. Braun
Journal: Cancer Immunology Research
Cancer Immunol Res (2023) 11 (8): 1114–1124.
https://doi.org/10.1158/2326-6066.CIR-22-0996
Published: 03 August 2023
View article titled, Circulating and Intratumoral Immune Determinants of Response to Atezolizumab plus Bevacizumab in Patients with Variant Histology or Sarcomatoid Renal Cell Carcinoma
Open the PDF for Circulating and Intratumoral Immune Determinants of Response to Atezolizumab plus Bevacizumab in Patients with Variant Histology or Sarcomatoid Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer

Carlos R. Gil Del Alcazar, Anne Trinh, Maša Alečković, Ernesto Rojas Jimenez, Nicholas W. Harper, Michael U.J. Oliphant, Shanshan Xie, Ethan D. Krop, Bethlehem Lulseged, Katherine C. Murphy, Tanya E. Keenan, Eliezer M. Van Allen, Sara M. Tolaney, Gordon J. Freeman, Deborah A. Dillon, Senthil K. Muthuswamy, Kornelia Polyak
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (6): 680–697.
https://doi.org/10.1158/2326-6066.CIR-21-0804
Published: 03 June 2022
View article titled, Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer
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Includes: Supplementary data
Journal Articles

Linking a Trio of Molecular Features in Clear-Cell Renal Cell Carcinoma

Chris Labaki, Eliezer M. Van Allen, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (3): 274.
https://doi.org/10.1158/2326-6066.CIR-22-0058
Published: 01 March 2022
View article titled, Linking a Trio of Molecular Features in Clear-Cell Renal Cell Carcinoma
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Journal Articles

Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors

Sarah Abou Alaiwi, Amin H. Nassar, Wanling Xie, Ziad Bakouny, Jacob E. Berchuck, David A. Braun, Sylvan C. Baca, Pier Vitale Nuzzo, Ronan Flippot, Tarek H. Mouhieddine, Liam F. Spurr, Yvonne Y. Li, Taiwen Li, Abdallah Flaifel, John A. Steinharter, Claire A. Margolis, Natalie I. Vokes, Heng Du, Sachet A. Shukla, Andrew D. Cherniack, Guru Sonpavde, Robert I. Haddad, Mark M. Awad, Marios Giannakis, F. Stephen Hodi, X. Shirley Liu, Sabina Signoretti, Cigall Kadoch, Matthew L. Freedman, David J. Kwiatkowski, Eliezer M. Van Allen, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (8): 1075–1084.
https://doi.org/10.1158/2326-6066.CIR-19-0866
Published: 03 August 2020
View article titled, Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors
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Includes: Supplementary data
Journal Articles

Abstract A48: Inactivation of Fbxw7 impairs dsRNA sensing and confers resistance to PD-1 blockade

Cécile Gstalder, David Liu, Diana Miao, Alexander Devine, Bart Lutterbach, Priya Pancholi, Megha Shettigar, Elizabeth Buchbinder, Scott Carter, Michael Manos, Vanesa Rojas-Rudilla, Ryan Brennick, Evisa Gjini, Ana Lako, Scott Rodig, Charles Yoon, Gordon Freeman, F. Stephen Hodi, Eliezer M. Van Allen, Rizwan Haq
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (3_Supplement): A48.
https://doi.org/10.1158/2326-6074.TUMIMM19-A48
Published: 02 March 2020
View article titled, Abstract A48: Inactivation of <em>Fbxw7</em> impairs dsRNA sensing and confers resistance to PD-1 blockade
Journal Articles

Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

Carino Gurjao, David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su, Kristen Felt, Evisa Gjini, Lauren K. Brais, Asaf Rotem, Michael H. Rosenthal, Orit Rozenblatt-Rosen, Scott Rodig, Kimmie Ng, Eliezer M. Van Allen, Steven M. Corsello, Shuji Ogino, Aviv Regev, Jonathan A. Nowak, Marios Giannakis
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (8): 1230–1236.
https://doi.org/10.1158/2326-6066.CIR-18-0683
Published: 01 August 2019
View article titled, Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Abstract A082: Single-cell RNA-sequencing of metastatic melanoma identifies a cancer cell-intrinsic program associated with immune checkpoint inhibitor resistance

Livnat Jerby, Parin Shah, Michael S. Cuoco, Christopher Rodman, Mei-Ju Su, Johannes M. Melms, Rachel Leeson, Abhay Kanodia, Shaolin Mei, Jia-Ren Lin, Shu Wang, Bokang Rabasha, David Liu, Gao Zhang, Claire Margolais, Orr Ashenberg, Patrick A. Ott, Elizabeth I. Buchbinder, Riz Haq, Stephen Hodi, Genevieve M. Boland, Ryan J. Sullivan, Dennie Frederick, Benchun Miao, Tabea Moll, Keith Flaherty, Meenhard Herlyn, Russell S. Jenkins, Rohit Thummalapalli, Monika S. Kowalczyk, Israel Canadas, Bastian Schilling, Adam N.R Cartwright, Adrienne M. Luoma, Shruti Malu, Patrick Hwu, Chantale Bernatchez, Marie-Andree Forget, David A. Barbie, Alex K. Shalek, Itay Tirosh, Peter K. Sorger, Kai W. Wucherpfennig, Eliezer M. Van Allen, Dirk Schadendorf, Bruce E. Johnson, Asaf Rotem, Orit Rosenblatt-Rozen, Levi A. Garraway, Charles H. Yoon, Benjamin Izar, Aviv Regev
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (2_Supplement): A082.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR18-A082
Published: 01 February 2019
View article titled, Abstract A082: Single-cell RNA-sequencing of metastatic melanoma identifies a cancer cell-intrinsic program associated with immune checkpoint inhibitor resistance
Journal Articles

Abstract IA26: Genomic correlates of response and resistance to immune checkpoint blockade

Eliezer M. Van Allen
Journal: Cancer Immunology Research
Cancer Immunol Res (2017) 5 (3_Supplement): IA26.
https://doi.org/10.1158/2326-6074.TUMIMM16-IA26
Published: 28 February 2017
View article titled, Abstract IA26: Genomic correlates of response and resistance to immune checkpoint blockade
Journal Articles

Tumor Mutational Load and Immune Parameters across Metastatic Renal Cell Carcinoma Risk Groups

Guillermo de Velasco, Diana Miao, Martin H. Voss, A. Ari Hakimi, James J. Hsieh, Nizar M. Tannir, Pheroze Tamboli, Leonard J. Appleman, W. Kimryn Rathmell, Eliezer M. Van Allen, Toni K. Choueiri
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (10): 820–822.
https://doi.org/10.1158/2326-6066.CIR-16-0110
Published: 02 October 2016
View article titled, Tumor Mutational Load and Immune Parameters across Metastatic Renal Cell Carcinoma Risk Groups
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Journal Articles

Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation

Eliezer M. Van Allen, Hadrien G. Golay, Yan Liu, Shohei Koyama, Karrie Wong, Amaro Taylor-Weiner, Marios Giannakis, Maegan Harden, Vanesa Rojas-Rudilla, Aaron Chevalier, Tran Thai, Christine Lydon, Stacy Mach, Ada G. Avila, Joshua A. Wong, Alexandra R. Rabin, Joshua Helmkamp, Lynette Sholl, Scott L. Carter, Geoffrey Oxnard, Pasi Janne, Gad Getz, Neal Lindeman, Peter S. Hammerman, Levi A. Garraway, F. Stephen Hodi, Scott J. Rodig, Glenn Dranoff, Kwok-Kin Wong, David A. Barbie
Journal: Cancer Immunology Research
Series: Author Choice
Cancer Immunol Res (2015) 3 (8): 855–863.
https://doi.org/10.1158/2326-6066.CIR-15-0024
Published: 03 August 2015
View article titled, Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with <em>JAK3</em> Activation
Open the PDF for Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with <em>JAK3</em> Activation in another window
Includes: Supplementary data