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Christopher J. Nirschl
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Journal Articles

mWTX-330, an IL-12 INDUKINE Molecule, Activates and Reshapes Tumor-Infiltrating CD8 + T and NK Cells to Generate Antitumor Immunity

Christopher J. Nirschl, Heather R. Brodkin, Celesztina Domonkos, Connor J. Dwyer, Daniel J. Hicklin, Nesreen Ismail, Cynthia Seidel-Dugan, Philipp Steiner, Zoe Steuert, Jenna M. Sullivan, William M. Winston, Andres Salmeron
Journal: Cancer Immunology Research
Cancer Immunol Res OF1–OF16.
DOI: https://doi.org/10.1158/2326-6066.CIR-22-0705
Published: 18 May 2023
View article titled, mWTX-330, an IL-12 INDUKINE Molecule, Activates and Reshapes Tumor-Infiltrating CD8<sup> + </sup> T and NK Cells to Generate Antitumor Immunity
Click here to open pdf in another window PDF for mWTX-330, an IL-12 INDUKINE Molecule, Activates and Reshapes Tumor-Infiltrating CD8<sup> + </sup> T and NK Cells to Generate Antitumor Immunity
Includes: Supplementary data
Journal Articles

Discovery of a Conditionally Activated IL-2 that Promotes Antitumor Immunity and Induces Tumor Regression

Christopher J. Nirschl, Heather R. Brodkin, Daniel J. Hicklin, Nesreen Ismail, Kristin Morris, Cynthia Seidel-Dugan, Philipp Steiner, Zoe Steuert, Jenna M. Sullivan, Ethika Tyagi, William M. Winston, Andres Salmeron
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (5): 581–596.
DOI: https://doi.org/10.1158/2326-6066.CIR-21-0831
Published: 03 May 2022
View article titled, Discovery of a Conditionally Activated IL-2 that Promotes Antitumor Immunity and Induces Tumor Regression
Click here to open pdf in another window PDF for Discovery of a Conditionally Activated IL-2 that Promotes Antitumor Immunity and Induces Tumor Regression
Includes: Supplementary data
Journal Articles

PPARγ Contributes to Immunity Induced by Cancer Cell Vaccines That Secrete GM-CSF

Girija Goyal, Karrie Wong, Christopher J. Nirschl, Nicholas Souders, Donna Neuberg, Niroshana Anandasabapathy, Glenn Dranoff
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (6): 723–732.
DOI: https://doi.org/10.1158/2326-6066.CIR-17-0612
Published: 31 May 2018
View article titled, PPARγ Contributes to Immunity Induced by Cancer Cell Vaccines That Secrete GM-CSF
Click here to open pdf in another window PDF for PPARγ Contributes to Immunity Induced by Cancer Cell Vaccines That Secrete GM-CSF
Includes: Supplementary data
Journal Articles

Stereotactic Radiation Therapy Augments Antigen-Specific PD-1–Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen

Andrew B. Sharabi, Christopher J. Nirschl, Christina M. Kochel, Thomas R. Nirschl, Brian J. Francica, Esteban Velarde, Theodore L. Deweese, Charles G. Drake
Journal: Cancer Immunology Research
Cancer Immunol Res (2015) 3 (4): 345–355.
DOI: https://doi.org/10.1158/2326-6066.CIR-14-0196
Published: 05 April 2015
View article titled, Stereotactic Radiation Therapy Augments Antigen-Specific PD-1–Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen
Click here to open pdf in another window PDF for Stereotactic Radiation Therapy Augments Antigen-Specific PD-1–Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen
Includes: Supplementary data