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Benoit J. Van den Eynde
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Journal Articles

T Cell–Mediated Targeted Delivery of Anti–PD-L1 Nanobody Overcomes Poor Antibody Penetration and Improves PD-L1 Blocking at the Tumor Site

Pierre-Florent Petit, Raphaële Bombart, Pierre-Hubert Desimpel, Stefan Naulaerts, Laurie Thouvenel, Jean-François Collet, Benoit J. Van den Eynde, Jingjing Zhu
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (6): 713–727.
https://doi.org/10.1158/2326-6066.CIR-21-0801
Published: 03 June 2022
View article titled, T Cell–Mediated Targeted Delivery of Anti–PD-L1 Nanobody Overcomes Poor Antibody Penetration and Improves PD-L1 Blocking at the Tumor Site
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Includes: Supplementary data
Journal Articles

Navigating Critical Challenges Associated with Immunopeptidomics-Based Detection of Proteasomal Spliced Peptide Candidates

Cheryl F. Lichti, Nathalie Vigneron, Karl R. Clauser, Benoit J. Van den Eynde, Michal Bassani-Sternberg
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (3): 275–284.
https://doi.org/10.1158/2326-6066.CIR-21-0727
Published: 03 March 2022
View article titled, Navigating Critical Challenges Associated with Immunopeptidomics-Based Detection of Proteasomal Spliced Peptide Candidates
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Journal Articles

Abstract P025: Uncovering molecular actors of IDO-mediated T cell dysfunction with genome-wide CRISPR/Cas9 knockout screens

Raphaële Bombart, Jingjing Zhu, Benoit J. Van den Eynde
Journal: Cancer Immunology Research
Cancer Immunol Res (2022) 10 (1_Supplement): P025.
https://doi.org/10.1158/2326-6074.TUMIMM21-P025
Published: 01 January 2022
View article titled, Abstract P025: Uncovering molecular actors of IDO-mediated T cell dysfunction with genome-wide CRISPR/Cas9 knockout screens
Journal Articles

Arid5a: A Missing Link between EMT and Tumoral Immune Resistance

Benoit J. Van den Eynde
Journal: Cancer Immunology Research
Cancer Immunol Res (2021) 9 (8): 854.
https://doi.org/10.1158/2326-6066.CIR-21-0432
Published: 01 August 2021
View article titled, Arid5a: A Missing Link between EMT and Tumoral Immune Resistance
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Journal Articles

Tryptophan 2,3-Dioxygenase Expression Identified in Human Hepatocellular Carcinoma Cells and in Intratumoral Pericytes of Most Cancers

Delia Hoffmann, Tereza Dvorakova, Vincent Stroobant, Caroline Bouzin, Aurélie Daumerie, Marie Solvay, Simon Klaessens, Marie-Claire Letellier, Jean-Christophe Renauld, Nicolas van Baren, Julie Lelotte, Etienne Marbaix, Benoit J. Van den Eynde
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (1): 19–31.
https://doi.org/10.1158/2326-6066.CIR-19-0040
Published: 02 January 2020
View article titled, Tryptophan 2,3-Dioxygenase Expression Identified in Human Hepatocellular Carcinoma Cells and in Intratumoral Pericytes of Most Cancers
Open the PDF for Tryptophan 2,3-Dioxygenase Expression Identified in Human Hepatocellular Carcinoma Cells and in Intratumoral Pericytes of Most Cancers in another window
Includes: Supplementary data
Journal Articles

Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors

Florence Schramme, Stefano Crosignani, Kim Frederix, Delia Hoffmann, Luc Pilotte, Vincent Stroobant, Julie Preillon, Gregory Driessens, Benoit J. Van den Eynde
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (1): 32–45.
https://doi.org/10.1158/2326-6066.CIR-19-0041
Published: 02 January 2020
View article titled, Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors
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Includes: Supplementary data
Journal Articles

Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance

Marc Hennequart, Luc Pilotte, Stefania Cane, Delia Hoffmann, Vincent Stroobant, Etienne De Plaen, Benoît J. Van den Eynde
Journal: Cancer Immunology Research
Cancer Immunol Res (2017) 5 (8): 695–709.
https://doi.org/10.1158/2326-6066.CIR-16-0400
Published: 01 August 2017
View article titled, Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance
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Includes: Supplementary data
Journal Articles

Tumoral Immune Resistance Mediated by Enzymes That Degrade Tryptophan

Nicolas van Baren, Benoît J. Van den Eynde
Journal: Cancer Immunology Research
Cancer Immunol Res (2015) 3 (9): 978–985.
https://doi.org/10.1158/2326-6066.CIR-15-0095
Published: 03 September 2015
View article titled, Tumoral Immune Resistance Mediated by Enzymes That Degrade Tryptophan
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Journal Articles

Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues

Ivan Théate, Nicolas van Baren, Luc Pilotte, Pierre Moulin, Pierre Larrieu, Jean-Christophe Renauld, Caroline Hervé, Ilse Gutierrez-Roelens, Etienne Marbaix, Christine Sempoux, Benoît J. Van den Eynde
Journal: Cancer Immunology Research
Cancer Immunol Res (2015) 3 (2): 161–172.
https://doi.org/10.1158/2326-6066.CIR-14-0137
Published: 05 February 2015
View article titled, Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues
Open the PDF for Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues in another window
Includes: Supplementary data