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Barbara Savoldo
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Journal Articles

Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling

Free
Elisa Landoni, Giovanni Fucá, Jian Wang, Venkat R. Chirasani, Zhiyuan Yao, Elena Dukhovlinova, Soldano Ferrone, Barbara Savoldo, Lee K. Hong, Peishun Shou, Silvia Musio, Francesco Padelli, Gaetano Finocchiaro, Miriam Droste, Brian Kuhlman, Abdijapar Shamshiev, Serena Pellegatta, Nikolay V. Dokholyan, Gianpietro Dotti
Journal: Cancer Immunology Research
Cancer Immunol Res (2021) 9 (4): 441–453.
https://doi.org/10.1158/2326-6066.CIR-20-0451
Published: 01 April 2021
View articletitled, Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling
Open the PDF for Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling in another window
Includes: Supplementary data
Journal Articles

A High-Avidity T-cell Receptor Redirects Natural Killer T-cell Specificity and Outcompetes the Endogenous Invariant T-cell Receptor

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Elisa Landoni, Christof C. Smith, Giovanni Fucá, Yuhui Chen, Chuang Sun, Benjamin G. Vincent, Leonid S. Metelitsa, Gianpietro Dotti, Barbara Savoldo
Journal: Cancer Immunology Research
Cancer Immunol Res (2020) 8 (1): 57–69.
https://doi.org/10.1158/2326-6066.CIR-19-0134
Published: 02 January 2020
View articletitled, A High-Avidity T-cell Receptor Redirects Natural Killer T-cell Specificity and Outcompetes the Endogenous Invariant T-cell Receptor
Open the PDF for A High-Avidity T-cell Receptor Redirects Natural Killer T-cell Specificity and Outcompetes the Endogenous Invariant T-cell Receptor in another window
Includes: Supplementary data
Journal Articles

Machine-Learning Prediction of Tumor Antigen Immunogenicity in the Selection of Therapeutic Epitopes

Free
Christof C. Smith, Shengjie Chai, Amber R. Washington, Samuel J. Lee, Elisa Landoni, Kevin Field, Jason Garness, Lisa M. Bixby, Sara R. Selitsky, Joel S. Parker, Barbara Savoldo, Jonathan S. Serody, Benjamin G. Vincent
Journal: Cancer Immunology Research
Series: Author Choice
Cancer Immunol Res (2019) 7 (10): 1591–1604.
https://doi.org/10.1158/2326-6066.CIR-19-0155
Published: 01 October 2019
View articletitled, Machine-Learning Prediction of Tumor Antigen Immunogenicity in the Selection of Therapeutic Epitopes
Open the PDF for Machine-Learning Prediction of Tumor Antigen Immunogenicity in the Selection of Therapeutic Epitopes in another window
Includes: Supplementary data
Journal Articles

Cancer Immunotherapy with T Cells Carrying Bispecific Receptors That Mimic Antibodies

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Sarah Ahn, Jingjing Li, Chuang Sun, Keliang Gao, Koichi Hirabayashi, Hongxia Li, Barbara Savoldo, Rihe Liu, Gianpietro Dotti
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (5): 773–783.
https://doi.org/10.1158/2326-6066.CIR-18-0636
Published: 01 May 2019
View articletitled, Cancer Immunotherapy with T Cells Carrying Bispecific Receptors That Mimic Antibodies
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Includes: Supplementary data
Journal Articles

Abstract A025: Eradication of neuroblastoma by T-cells redirected with an optimized GD2-specific chimeric antigen receptor and IL-15

Free
Yuhui Chen, Chuang Sun, Leonid Metelitsa, Gianpietro Dotti, Barbara Savoldo
Journal: Cancer Immunology Research
Cancer Immunol Res (2019) 7 (2_Supplement): A025.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR18-A025
Published: 01 February 2019
View articletitled, Abstract A025: Eradication of neuroblastoma by T-cells redirected with an optimized GD2-specific chimeric antigen receptor and IL-15
Journal Articles

CD30-Redirected Chimeric Antigen Receptor T Cells Target CD30+ and CD30− Embryonal Carcinoma via Antigen-Dependent and Fas/FasL Interactions

Free
Lee K. Hong, Yuhui Chen, Christof C. Smith, Stephanie A. Montgomery, Benjamin G. Vincent, Gianpietro Dotti, Barbara Savoldo
Journal: Cancer Immunology Research
Cancer Immunol Res (2018) 6 (10): 1274–1287.
https://doi.org/10.1158/2326-6066.CIR-18-0065
Published: 02 October 2018
View articletitled, CD30-Redirected Chimeric Antigen Receptor T Cells Target CD30+ and CD30− Embryonal Carcinoma via Antigen-Dependent and Fas/FasL Interactions
Open the PDF for CD30-Redirected Chimeric Antigen Receptor T Cells Target CD30+ and CD30− Embryonal Carcinoma via Antigen-Dependent and Fas/FasL Interactions in another window
Includes: Supplementary data
Journal Articles

Abstract A041: CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia – report from the Swedish phase I/IIa trial

Free
Gunilla Enblad, Hannah Karlsson, Kristina I. Wikstrom, Magnus Essand, Barbara Savoldo, Malcolm K. Brenner, Gianpietro Dotti, Martin Hoglund, Hans Hagberg, Angelica Loskog
Journal: Cancer Immunology Research
Cancer Immunol Res (2016) 4 (1_Supplement): A041.
https://doi.org/10.1158/2326-6074.CRICIMTEATIAACR15-A041
Published: 03 January 2016
View articletitled, Abstract A041: CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia – report from the Swedish phase I/IIa trial