About the Cover
This issue of Cancer Immunology Research includes a Cancer Immunology at the Crossroads article that highlights two of the many ways in which tumors can evade immune surveilliance. Both of these “tricks” employ the repurposing of how two elements, oxygen and potassium, engage with the tumor microenvironment and the resultant suppression of antitumor immune responses. Read more in Gurusamy et al., beginning on page 426. The original image is of a resected metastatic colon tumor stained with hematoxylin and eosin. Photo from the Restifo laboratory. Artwork by Lewis Long.