About the Cover
In their article in the current issue, Khare and colleagues report that the receptor subunit shared by IL10 and IL22 is a key factor in the development of colorectal cancer. This “satellite image”–like rendition of the colon is based on a panel from their Fig. 4. Read more about the complex interplay between the shared and unique receptor subunits that generate the signals necessary for tumorigenesis in this research article on pages 1227–1235 in this issue of Cancer Immunology Research. Original micrograph from Gregor Paul, artwork by Lewis Long.