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Journal Articles

Prostate Cancer Transcriptomic Regulation by the Interplay of Germline Risk Alleles, Somatic Mutations, and 3D Genomic Architecture

Jiapei Yuan, Kathleen E. Houlahan, Susmita G. Ramanand, Sora Lee, GuemHee Baek, Yang Yang, Yong Chen, Douglas W. Strand, Michael Q. Zhang, Paul C. Boutros, Ram S. Mani
Journal: Cancer Discovery
Cancer Discov (2022) 12 (12): 2838–2855.
https://doi.org/10.1158/2159-8290.CD-22-0027
Published: 02 December 2022
View article titled, Prostate Cancer Transcriptomic Regulation by the Interplay of Germline Risk Alleles, Somatic Mutations, and 3D Genomic Architecture
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Includes: Supplementary data
Journal Articles

Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS–MAPK Pathway Inhibition in Pancreatic Cancer

Mirunalini Ravichandran, Jingjie Hu, Charles Cai, Nathan P. Ward, Anthony Venida, Callum Foakes, Miljan Kuljanin, Annan Yang, Connor J. Hennessey, Yang Yang, Brandon R. Desousa, Gilles Rademaker, Annelot A.L. Staes, Zeynep Cakir, Isha H. Jain, Andrew J. Aguirre, Joseph D. Mancias, Yin Shen, Gina M. DeNicola, Rushika M. Perera
Journal: Cancer Discovery
Cancer Discov (2022) 12 (9): 2198–2219.
https://doi.org/10.1158/2159-8290.CD-22-0044
Published: 02 September 2022
View article titled, Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS–MAPK Pathway Inhibition in Pancreatic Cancer
Open the PDF for Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS–MAPK Pathway Inhibition in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy

Gregory M. Chen, Changya Chen, Rajat K. Das, Peng Gao, Chia-Hui Chen, Shovik Bandyopadhyay, Yang-Yang Ding, Yasin Uzun, Wenbao Yu, Qin Zhu, Regina M. Myers, Stephan A. Grupp, David M. Barrett, Kai Tan
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (9): 2186–2199.
https://doi.org/10.1158/2159-8290.CD-20-1677
Published: 01 September 2021
View article titled, Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy
Open the PDF for Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy in another window
Includes: Supplementary data
Journal Articles

Autocrine Complement Inhibits IL10-Dependent T-cell–Mediated Antitumor Immunity to Promote Tumor Progression

Yu Wang, Sheng-Nan Sun, Qing Liu, Yang-Yang Yu, Jian Guo, Kun Wang, Bao-Cai Xing, Qing-Feng Zheng, Michael J. Campa, Edward F. Patz, Jr, Shi-You Li, You-Wen He
Journal: Cancer Discovery
Cancer Discov (2016) 6 (9): 1022–1035.
https://doi.org/10.1158/2159-8290.CD-15-1412
Published: 31 August 2016
View article titled, Autocrine Complement Inhibits IL10-Dependent T-cell–Mediated Antitumor Immunity to Promote Tumor Progression
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Includes: Supplementary data