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Yan Wang
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Journal Articles

Expression of Concern: Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity

Aayoung Hong, Marco Piva, Sixue Liu, Willy Hugo, Shirley H. Lomeli, Vincent Zoete, Christopher E. Randolph, Zhentao Yang, Yan Wang, Jordan J. Lee, Skylar J. Lo, Lu Sun, Agustin Vega-Crespo, Alejandro J. Garcia, David B. Shackelford, Steven M. Dubinett, Philip O. Scumpia, Stephanie D. Byrum, Alan J. Tackett, Timothy R. Donahue, Olivier Michielin, Sheri L. Holmen, Antoni Ribas, Gatien Moriceau, Roger S. Lo
Journal: Cancer Discovery
Cancer Discov (2024) 14 (7): 1357.
https://doi.org/10.1158/2159-8290.CD-24-0613
Published: 01 July 2024
View articletitled, Expression of Concern: Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity
Open the PDF for Expression of Concern: Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity in another window
Journal Articles

Blocking Genomic Instability Prevents Acquired Resistance to MAPK Inhibitor Therapy in Melanoma

Prashanthi Dharanipragada, Xiao Zhang, Sixue Liu, Shirley H. Lomeli, Aayoung Hong, Yan Wang, Zhentao Yang, Kara Z. Lo, Agustin Vega-Crespo, Antoni Ribas, Stergios J. Moschos, Gatien Moriceau, Roger S. Lo
Journal: Cancer Discovery
Cancer Discov (2023) 13 (4): 880–909.
https://doi.org/10.1158/2159-8290.CD-22-0787
Published: 03 April 2023
View articletitled, Blocking Genomic Instability Prevents Acquired Resistance to MAPK Inhibitor Therapy in Melanoma
Open the PDF for Blocking Genomic Instability Prevents Acquired Resistance to MAPK Inhibitor Therapy in Melanoma in another window
Includes: Supplementary data
Journal Articles

Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance

Zhentao Yang, Yan Wang, Sixue Liu, Weixian Deng, Shirley H. Lomeli, Gatien Moriceau, James Wohlschlegel, Marco Piva, Roger S. Lo
Journal: Cancer Discovery
Cancer Discov (2022) 12 (8): 1942–1959.
https://doi.org/10.1158/2159-8290.CD-21-1463
Published: 05 August 2022
View articletitled, Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
Open the PDF for Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance in another window
Includes: Supplementary data
Journal Articles

Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity

Aayoung Hong, Marco Piva, Sixue Liu, Willy Hugo, Shirley H. Lomeli, Vincent Zoete, Christopher E. Randolph, Zhentao Yang, Yan Wang, Jordan J. Lee, Skylar J. Lo, Lu Sun, Agustin Vega-Crespo, Alejandro J. Garcia, David B. Shackelford, Steven M. Dubinett, Philip O. Scumpia, Stephanie D. Byrum, Alan J. Tackett, Timothy R. Donahue, Olivier Michielin, Sheri L. Holmen, Antoni Ribas, Gatien Moriceau, Roger S. Lo
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (3): 714–735.
https://doi.org/10.1158/2159-8290.CD-20-0873
Published: 02 March 2021
View articletitled, Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity
Open the PDF for Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity in another window
Includes: Supplementary data