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Journal Articles

Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma

Michal Marek Hoppe, Patrick Jaynes, Fan Shuangyi, Yanfen Peng, Shruti Sridhar, Phuong Mai Hoang, Clementine Xin Liu, Sanjay De Mel, Limei Poon, Esther Hian Li Chan, Joanne Lee, Choon Kiat Ong, Tiffany Tang, Soon Thye Lim, Chandramouli Nagarajan, Nicholas F. Grigoropoulos, Soo-Yong Tan, Susan Swee-Shan Hue, Sheng-Tsung Chang, Shih-Sung Chuang, Shaoying Li, Joseph D. Khoury, Hyungwon Choi, Carl Harris, III, Alessia Bottos, Laura J. Gay, Hendrik F.P. Runge, Ilias Moutsopoulos, Irina Mohorianu, Daniel J. Hodson, Pedro Farinha, Anja Mottok, David W. Scott, Jason J. Pitt, Jinmiao Chen, Gayatri Kumar, Kasthuri Kannan, Wee Joo Chng, Yen Lin Chee, Siok-Bian Ng, Claudio Tripodo, Anand D. Jeyasekharan
Journal: Cancer Discovery
Cancer Discov (2023) 13 (5): 1144–1163.
https://doi.org/10.1158/2159-8290.CD-22-0998
Published: 04 May 2023
View article titled, Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma
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Includes: Supplementary data
Journal Articles

Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance

Junhua Lyu, Yuxuan Liu, Lihu Gong, Mingyi Chen, Yazan F. Madanat, Yuannyu Zhang, Feng Cai, Zhimin Gu, Hui Cao, Pranita Kaphle, Yoon Jung Kim, Fatma N. Kalkan, Helen Stephens, Kathryn E. Dickerson, Min Ni, Weina Chen, Prapti Patel, Alice S. Mims, Uma Borate, Amy Burd, Sheng F. Cai, C. Cameron Yin, M. James You, Stephen S. Chung, Robert H. Collins, Ralph J. DeBerardinis, Xin Liu, Jian Xu
Journal: Cancer Discovery
Cancer Discov (2023) 13 (1): 170–193.
https://doi.org/10.1158/2159-8290.CD-21-1661
Published: 09 January 2023
View article titled, Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance
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Includes: Supplementary data
Journal Articles

Serial Profiling of Circulating Tumor DNA Identifies Dynamic Evolution of Clinically Actionable Genomic Alterations in High-Risk Neuroblastoma

Kristopher R. Bosse, Anna Maria Giudice, Maria V. Lane, Brendan McIntyre, Patrick M. Schürch, Guillem Pascual-Pasto, Samantha N. Buongervino, Sriyaa Suresh, Alana Fitzsimmons, Adam Hyman, Maria Gemino-Borromeo, Jennifer Saggio, Esther R. Berko, Alexander A. Daniels, Jennifer Stundon, Megan Friedrichsen, Xin Liu, Matthew L. Margolis, Marilyn M. Li, Marni Brisson Tierno, Geoffrey R. Oxnard, John M. Maris, Yael P. Mossé
Journal: Cancer Discovery
Cancer Discov (2022) 12 (12): 2800–2819.
https://doi.org/10.1158/2159-8290.CD-22-0287
Published: 02 December 2022
View article titled, Serial Profiling of Circulating Tumor DNA Identifies Dynamic Evolution of Clinically Actionable Genomic Alterations in High-Risk Neuroblastoma
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Includes: Supplementary data
Journal Articles

Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies

Kailong Li, Yuannyu Zhang, Xin Liu, Yuxuan Liu, Zhimin Gu, Hui Cao, Kathryn E. Dickerson, Mingyi Chen, Weina Chen, Zhen Shao, Min Ni, Jian Xu
Journal: Cancer Discovery
Cancer Discov (2020) 10 (5): 724–745.
https://doi.org/10.1158/2159-8290.CD-19-1128
Published: 01 May 2020
View article titled, Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies
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Includes: Supplementary data
Journal Articles

Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation

Zhimin Gu, Yuxuan Liu, Feng Cai, McKenzie Patrick, Jakub Zmajkovic, Hui Cao, Yuannyu Zhang, Alpaslan Tasdogan, Mingyi Chen, Le Qi, Xin Liu, Kailong Li, Junhua Lyu, Kathryn E. Dickerson, Weina Chen, Min Ni, Matthew E. Merritt, Sean J. Morrison, Radek C. Skoda, Ralph J. DeBerardinis, Jian Xu
Journal: Cancer Discovery
Cancer Discov (2019) 9 (9): 1228–1247.
https://doi.org/10.1158/2159-8290.CD-19-0152
Published: 03 September 2019
View article titled, Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
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Includes: Supplementary data
Journal Articles

Developing EZH2-Targeted Therapy for Lung Cancer

Arthur E. Frankel, Xin Liu, John D. Minna
Journal: Cancer Discovery
Cancer Discov (2016) 6 (9): 949–952.
https://doi.org/10.1158/2159-8290.CD-16-0800
Published: 31 August 2016
View article titled, Developing EZH2-Targeted Therapy for Lung Cancer
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