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Xiaoying Shang
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Journal Articles

Combined KRAS Inhibition and Immune Therapy Generates Durable Complete Responses in an Autochthonous PDAC Model

Yonghong Liu, Jincheng Han, Wen-Hao Hsu, Kyle A. LaBella, Pingna Deng, Xiaoying Shang, Paulino Tallón de Lara, Li Cai, Shan Jiang, Ronald A. DePinho
Journal: Cancer Discovery
Cancer Discov (2025) 15 (1): 162–178.
https://doi.org/10.1158/2159-8290.CD-24-0489
Published: 13 January 2025
View article titled, Combined KRAS Inhibition and Immune Therapy Generates Durable Complete Responses in an Autochthonous PDAC Model
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Includes: Supplementary data
Journal Articles

Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression

Wen-Hao Hsu, Kyle A. LaBella, Yiyun Lin, Ping Xu, Rumi Lee, Cheng-En Hsieh, Lei Yang, Ashley Zhou, Jonathan M. Blecher, Chang-Jiun Wu, Kangyu Lin, Xiaoying Shang, Shan Jiang, Denise J. Spring, Yan Xia, Peiwen Chen, John Paul Shen, Scott Kopetz, Ronald A. DePinho
Journal: Cancer Discovery
Cancer Discov (2023) 13 (12): 2652–2673.
https://doi.org/10.1158/2159-8290.CD-22-1467
Published: 12 December 2023
View article titled, Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression
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Includes: Supplementary data
Journal Articles

Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer

Di Zhao, Li Cai, Xin Lu, Xin Liang, Jiexi Li, Peiwen Chen, Michael Ittmann, Xiaoying Shang, Shan Jiang, Haoyan Li, Chenling Meng, Ivonne Flores, Jian H. Song, James W. Horner, Zhengdao Lan, Chang-Jiun Wu, Jun Li, Qing Chang, Ko-Chien Chen, Guocan Wang, Pingna Deng, Denise J. Spring, Y. Alan Wang, Ronald A. DePinho
Journal: Cancer Discovery
Cancer Discov (2020) 10 (9): 1374–1387.
https://doi.org/10.1158/2159-8290.CD-19-1352
Published: 01 September 2020
View article titled, Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer
Open the PDF for Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment

Prasenjit Dey, Jun Li, Jianhua Zhang, Surendra Chaurasiya, Anders Strom, Huamin Wang, Wen-Ting Liao, Frederick Cavallaro, Parker Denz, Vincent Bernard, Er-Yen Yen, Giannicola Genovese, Pat Gulhati, Jielin Liu, Deepavali Chakravarti, Pingna Deng, Tingxin Zhang, Federica Carbone, Qing Chang, Haoqiang Ying, Xiaoying Shang, Denise J. Spring, Bidyut Ghosh, Nagireddy Putluri, Anirban Maitra, Y. Alan Wang, Ronald A. DePinho
Journal: Cancer Discovery
Cancer Discov (2020) 10 (4): 608–625.
https://doi.org/10.1158/2159-8290.CD-19-0297
Published: 01 April 2020
View article titled, Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment
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Includes: Supplementary data
Journal Articles

Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression

Guocan Wang, Xin Lu, Prasenjit Dey, Pingna Deng, Chia Chin Wu, Shan Jiang, Zhuangna Fang, Kun Zhao, Ramakrishna Konaparthi, Sujun Hua, Jianhua Zhang, Elsa M. Li-Ning-Tapia, Avnish Kapoor, Chang-Jiun Wu, Neelay Bhaskar Patel, Zhenglin Guo, Vandhana Ramamoorthy, Trang N. Tieu, Tim Heffernan, Di Zhao, Xiaoying Shang, Sunada Khadka, Pingping Hou, Baoli Hu, Eun-Jung Jin, Wantong Yao, Xiaolu Pan, Zhihu Ding, Yanxia Shi, Liren Li, Qing Chang, Patricia Troncoso, Christopher J. Logothetis, Mark J. McArthur, Lynda Chin, Y. Alan Wang, Ronald A. DePinho
Journal: Cancer Discovery
Cancer Discov (2016) 6 (1): 80–95.
https://doi.org/10.1158/2159-8290.CD-15-0224
Published: 07 January 2016
View article titled, Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression
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Includes: Supplementary data