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X. Shirley Liu
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Journal Articles

Addressing Tumor Heterogeneity by Sensitizing Resistant Cancer Cells to T cell–Secreted Cytokines

Yoshinaga Ito, Deng Pan, Wubing Zhang, Xixi Zhang, Tiffany Y. Juan, Jason W. Pyrdol, Oleksandr Kyrysyuk, John G. Doench, X. Shirley Liu, Kai W. Wucherpfennig
Journal: Cancer Discovery
Cancer Discov (2023) 13 (5): 1186–1209.
https://doi.org/10.1158/2159-8290.CD-22-1125
Published: 04 May 2023
View article titled, Addressing Tumor Heterogeneity by Sensitizing Resistant Cancer Cells to T cell–Secreted Cytokines
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Includes: Supplementary data
Journal Articles

Discovery of Targets for Immune–Metabolic Antitumor Drugs Identifies Estrogen-Related Receptor Alpha

Avinash Sahu, Xiaoman Wang, Phillip Munson, Jan P.G. Klomp, Xiaoqing Wang, Shengqing Stan Gu, Ya Han, Gege Qian, Phillip Nicol, Zexian Zeng, Chenfei Wang, Collin Tokheim, Wubing Zhang, Jingxin Fu, Jin Wang, Nishanth Ulhas Nair, Joost A.P. Rens, Meriem Bourajjaj, Bas Jansen, Inge Leenders, Jaap Lemmers, Mark Musters, Sanne van Zanten, Laura van Zelst, Jenny Worthington, Jun S. Liu, Dejan Juric, Clifford A. Meyer, Arthur Oubrie, X. Shirley Liu, David E. Fisher, Keith T. Flaherty
Journal: Cancer Discovery
Cancer Discov (2023) 13 (3): 672–701.
https://doi.org/10.1158/2159-8290.CD-22-0244
Published: 01 March 2023
View article titled, Discovery of Targets for Immune–Metabolic Antitumor Drugs Identifies Estrogen-Related Receptor Alpha
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Includes: Supplementary data
Journal Articles

A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin–MLL Inhibition

Yadira M. Soto-Feliciano, Francisco J. Sánchez-Rivera, Florian Perner, Douglas W. Barrows, Edward R. Kastenhuber, Yu-Jui Ho, Thomas Carroll, Yijun Xiong, Disha Anand, Alexey A. Soshnev, Leah Gates, Mary Clare Beytagh, David Cheon, Shengqing Gu, X. Shirley Liu, Andrei V. Krivtsov, Maximiliano Meneses, Elisa de Stanchina, Richard M. Stone, Scott A. Armstrong, Scott W. Lowe, C. David Allis
Journal: Cancer Discovery
Cancer Discov (2023) 13 (1): 146–169.
https://doi.org/10.1158/2159-8290.CD-22-0416
Published: 09 January 2023
View article titled, A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin–MLL Inhibition
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Includes: Supplementary data
Journal Articles

CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells

Sushil Kumar, Zexian Zeng, Archis Bagati, Rong En Tay, Lionel A. Sanz, Stella R. Hartono, Yoshinaga Ito, Fieda Abderazzaq, Elodie Hatchi, Peng Jiang, Adam N.R. Cartwright, Olamide Olawoyin, Nathan D. Mathewson, Jason W. Pyrdol, Mamie Z. Li, John G. Doench, Matthew A. Booker, Michael Y. Tolstorukov, Stephen J. Elledge, Frédéric Chédin, X. Shirley Liu, Kai W. Wucherpfennig
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (8): 2050–2071.
https://doi.org/10.1158/2159-8290.CD-20-1144
Published: 01 August 2021
View article titled, CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells
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Includes: Supplementary data
Journal Articles

Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade

Shengqing Stan Gu, Wubing Zhang, Xiaoqing Wang, Peng Jiang, Nicole Traugh, Ziyi Li, Clifford Meyer, Blair Stewig, Yingtian Xie, Xia Bu, Michael P. Manos, Alba Font-Tello, Evisa Gjini, Ana Lako, Klothilda Lim, Jake Conway, Alok K. Tewari, Zexian Zeng, Avinash Das Sahu, Collin Tokheim, Jason L. Weirather, Jingxin Fu, Yi Zhang, Benjamin Kroger, Jin Hua Liang, Paloma Cejas, Gordon J. Freeman, Scott Rodig, Henry W. Long, Benjamin E. Gewurz, F. Stephen Hodi, Myles Brown, X. Shirley Liu
Journal: Cancer Discovery
Cancer Discov (2021) 11 (6): 1524–1541.
https://doi.org/10.1158/2159-8290.CD-20-0812
Published: 01 June 2021
View article titled, Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade
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Includes: Supplementary data
Journal Articles

Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma

Alexander Stoeck, Serguei Lejnine, Andrew Truong, Li Pan, Hongfang Wang, Chongzhi Zang, Jing Yuan, Chris Ware, John MacLean, Philip W. Garrett-Engele, Michael Kluk, Jason Laskey, Brian B. Haines, Christopher Moskaluk, Leigh Zawel, Stephen Fawell, Gary Gilliland, Theresa Zhang, Brandon E. Kremer, Birgit Knoechel, Bradley E. Bernstein, Warren S. Pear, X. Shirley Liu, Jon C. Aster, Sriram Sathyanarayanan
Journal: Cancer Discovery
Cancer Discov (2014) 4 (10): 1154–1167.
https://doi.org/10.1158/2159-8290.CD-13-0830
Published: 30 September 2014
View article titled, Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma
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Includes: Supplementary data