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William H. Yong
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Journal Articles

De-Repression of PDGFRβ Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients

Available to Purchase
David Akhavan, Alexandra L. Pourzia, Alex A. Nourian, Kevin J. Williams, David Nathanson, Ivan Babic, Genaro R. Villa, Kazuhiro Tanaka, Ali Nael, Huijun Yang, Julie Dang, Harry V. Vinters, William H. Yong, Mitchell Flagg, Fuyuhiko Tamanoi, Takashi Sasayama, C. David James, Harley I. Kornblum, Tim F. Cloughesy, Webster K. Cavenee, Steven J. Bensinger, Paul S. Mischel
Journal: Cancer Discovery
Cancer Discov (2013) 3 (5): 534–547.
https://doi.org/10.1158/2159-8290.CD-12-0502
Published: 08 May 2013
View articletitled, De-Repression of PDGFRβ Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients
Open the PDF for De-Repression of PDGFRβ Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients in another window
Includes: Supplementary data
Journal Articles

Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors

Free
Igor Vivanco, H. Ian Robins, Daniel Rohle, Carl Campos, Christian Grommes, Phioanh Leia Nghiemphu, Sara Kubek, Barbara Oldrini, Milan G. Chheda, Nicolas Yannuzzi, Hui Tao, Shaojun Zhu, Akio Iwanami, Daisuke Kuga, Julie Dang, Alicia Pedraza, Cameron W. Brennan, Adriana Heguy, Linda M. Liau, Frank Lieberman, W. K. Alfred Yung, Mark R. Gilbert, David A. Reardon, Jan Drappatz, Patrick Y. Wen, Kathleen R. Lamborn, Susan M. Chang, Michael D. Prados, Howard A. Fine, Steve Horvath, Nian Wu, Andrew B. Lassman, Lisa M. DeAngelis, William H. Yong, John G. Kuhn, Paul S. Mischel, Minesh P. Mehta, Timothy F. Cloughesy, Ingo K. Mellinghoff
Journal: Cancer Discovery
Cancer Discov (2012) 2 (5): 458–471.
https://doi.org/10.1158/2159-8290.CD-11-0284
Published: 09 May 2012
View articletitled, Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors
Open the PDF for Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors in another window
Includes: Multimedia, Supplementary data
Journal Articles

Oncogenic EGFR Signaling Activates an mTORC2–NF-κB Pathway That Promotes Chemotherapy Resistance

Free
Kazuhiro Tanaka, Ivan Babic, David Nathanson, David Akhavan, Deliang Guo, Beatrice Gini, Julie Dang, Shaojun Zhu, Huijun Yang, Jason De Jesus, Ali Nael Amzajerdi, Yinan Zhang, Christian C. Dibble, Hancai Dan, Amanda Rinkenbaugh, William H. Yong, Harry V. Vinters, Joseph F. Gera, Webster K. Cavenee, Timothy F. Cloughesy, Brendan D. Manning, Albert S. Baldwin, Paul S. Mischel
Journal: Cancer Discovery
Cancer Discov (2011) 1 (6): 524–538.
https://doi.org/10.1158/2159-8290.CD-11-0124
Published: 16 November 2011
View articletitled, Oncogenic EGFR Signaling Activates an mTORC2–NF-κB Pathway That Promotes Chemotherapy Resistance
Open the PDF for Oncogenic EGFR Signaling Activates an mTORC2–NF-κB Pathway That Promotes Chemotherapy Resistance in another window
Includes: Multimedia, Supplementary data