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Vaibhav Sahai
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Journal Articles

RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations

Vivek Subbiah, Vaibhav Sahai, Dejan Maglic, Kamil Bruderek, B. Barry Touré, Songping Zhao, Roberto Valverde, Patrick J. O'Hearn, Demetri T. Moustakas, Heike Schönherr, Nastaran Gerami-Moayed, Alexander M. Taylor, Brandi M. Hudson, Damian J. Houde, Debjani Pal, Lindsey Foster, Hakan Gunaydin, Pelin Ayaz, Dina A. Sharon, Lipika Goyal, Alison M. Schram, Suneel Kamath, Cori Ann Sherwin, Oleg Schmidt-Kittler, Kai Yu Jen, Fabien Ricard, Beni B. Wolf, David E. Shaw, Donald A. Bergstrom, James Watters, Jessica B. Casaletto
Journal: Cancer Discovery
Cancer Discov (2023) 13 (9): 2012–2031.
https://doi.org/10.1158/2159-8290.CD-23-0475
Published: 06 September 2023
View articletitled, RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations
Open the PDF for RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations in another window
Includes: Multimedia, Supplementary data
Journal Articles

Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions

Eileen S. Carpenter, Ahmed M. Elhossiny, Padma Kadiyala, Jay Li, Jake McGue, Brian D. Griffith, Yaqing Zhang, Jacob Edwards, Sarah Nelson, Fatima Lima, Katelyn L. Donahue, Wenting Du, Allison C. Bischoff, Danyah Alomari, Hannah R. Watkoske, Michael Mattea, Stephanie The, Carlos E. Espinoza, Meredith Barrett, Christopher J. Sonnenday, Nicholas Olden, Chin-Tung Chen, Nicole Peterson, Valerie Gunchick, Vaibhav Sahai, Arvind Rao, Filip Bednar, Jiaqi Shi, Timothy L. Frankel, Marina Pasca di Magliano
Journal: Cancer Discovery
Cancer Discov (2023) 13 (6): 1324–1345.
https://doi.org/10.1158/2159-8290.CD-23-0013
Published: 02 June 2023
View articletitled, Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions
Open the PDF for Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions in another window
Includes: Supplementary data
Journal Articles

GM-CSF Mediates Mesenchymal–Epithelial Cross-talk in Pancreatic Cancer

Meghna Waghray, Malica Yalamanchili, Michele Dziubinski, Mina Zeinali, Marguerite Erkkinen, Huibin Yang, Kara A. Schradle, Sumithra Urs, Marina Pasca Di Magliano, Theodore H. Welling, Phillip L. Palmbos, Ethan V. Abel, Vaibhav Sahai, Sunitha Nagrath, Lidong Wang, Diane M. Simeone
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2016) 6 (8): 886–899.
https://doi.org/10.1158/2159-8290.CD-15-0947
Published: 01 August 2016
View articletitled, GM-CSF Mediates Mesenchymal–Epithelial Cross-talk in Pancreatic Cancer
Open the PDF for GM-CSF Mediates Mesenchymal–Epithelial Cross-talk in Pancreatic Cancer in another window
Includes: Supplementary data