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Timothy P. Heffron
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Journal Articles

RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy

Kyung W. Song, Kyle A. Edgar, Emily J. Hanan, Marc Hafner, Jason Oeh, Mark Merchant, Deepak Sampath, Michelle A. Nannini, Rebecca Hong, Lilian Phu, William F. Forrest, Eric Stawiski, Stephen Schmidt, Nicholas Endres, Jane Guan, Jeffrey J. Wallin, Jonathan Cheong, Emile G. Plise, Gail D. Lewis Phillips, Laurent Salphati, Timothy P. Heffron, Alan G. Olivero, Shiva Malek, Steven T. Staben, Donald S. Kirkpatrick, Anwesha Dey, Lori S. Friedman
Journal: Cancer Discovery
Cancer Discov (2022) 12 (1): 204–219.
https://doi.org/10.1158/2159-8290.CD-21-0072
Published: 01 January 2022
View article titled, RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy
Open the PDF for RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy in another window
Includes: Supplementary data
Journal Articles

Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M

Ho-June Lee, Gabriele Schaefer, Timothy P. Heffron, Lily Shao, Xiaofen Ye, Steve Sideris, Shiva Malek, Emily Chan, Mark Merchant, Hank La, Savita Ubhayakar, Robert L. Yauch, Valentina Pirazzoli, Katerina Politi, Jeff Settleman
Journal: Cancer Discovery
Cancer Discov (2013) 3 (2): 168–181.
https://doi.org/10.1158/2159-8290.CD-12-0357
Published: 10 February 2013
View article titled, Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M
Open the PDF for Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M in another window
Includes: Supplementary data