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Stephen Gottschalk
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Journal Articles

Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages

Taylor L. Wilson, Hyunjin Kim, Ching-Heng Chou, Deanna Langfitt, Robert C. Mettelman, Anastasia A. Minervina, E. Kaitlynn Allen, Jean-Yves Métais, Mikhail V. Pogorelyy, Janice M. Riberdy, M. Paulina Velasquez, Pratibha Kottapalli, Sanchit Trivedi, Scott R. Olsen, Timothy Lockey, Catherine Willis, Michael M. Meagher, Brandon M. Triplett, Aimee C. Talleur, Stephen Gottschalk, Jeremy Chase Crawford, Paul G. Thomas
Journal: Cancer Discovery
Cancer Discov (2022) 12 (9): 2098–2119.
https://doi.org/10.1158/2159-8290.CD-21-1508
Published: 02 September 2022
View articletitled, Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages
Open the PDF for Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages in another window
Includes: Supplementary data
Journal Articles

A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function

Shannon Lange, Laurens G.L. Sand, Matthew Bell, Sagar L. Patil, Deanna Langfitt, Stephen Gottschalk
Journal: Cancer Discovery
Cancer Discov (2021) 11 (7): 1661–1671.
https://doi.org/10.1158/2159-8290.CD-20-0896
Published: 01 July 2021
View articletitled, A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function
Open the PDF for A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function in another window
Includes: Supplementary data
Journal Articles

Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells

Thomas Shum, Bilal Omer, Haruko Tashiro, Robert L. Kruse, Dimitrios L. Wagner, Kathan Parikh, Zhongzhen Yi, Tim Sauer, Daofeng Liu, Robin Parihar, Paul Castillo, Hao Liu, Malcolm K. Brenner, Leonid S. Metelitsa, Stephen Gottschalk, Cliona M. Rooney
Journal: Cancer Discovery
Cancer Discov (2017) 7 (11): 1238–1247.
https://doi.org/10.1158/2159-8290.CD-17-0538
Published: 01 November 2017
View articletitled, Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells
Open the PDF for Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells in another window
Includes: Supplementary data
Journal Articles

Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models

Melinda Mata, Claudia Gerken, Phuong Nguyen, Giedre Krenciute, David M. Spencer, Stephen Gottschalk
Journal: Cancer Discovery
Cancer Discov (2017) 7 (11): 1306–1319.
https://doi.org/10.1158/2159-8290.CD-17-0263
Published: 01 November 2017
View articletitled, Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models
Open the PDF for Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models in another window
Includes: Supplementary data