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Stefan M. Pfister
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Journal Articles

Cancer Neuroscience of Brain Tumors: From Multicellular Networks to Neuroscience-Instructed Cancer Therapies

Varun Venkataramani, Yvonne Yang, Sebastian Ille, Bogdana Suchorska, Sonja Loges, Heike Tost, Felix Sahm, Stefan M. Pfister, Andreas Trumpp, Sandro M. Krieg, Thomas Kuner, Wolfgang Wick, Frank Winkler
Journal: Cancer Discovery
Cancer Discov (2025) 15 (1): 39–51.
https://doi.org/10.1158/2159-8290.CD-24-0194
Published: 13 January 2025
View articletitled, Cancer Neuroscience of Brain Tumors: From Multicellular Networks to Neuroscience-Instructed Cancer Therapies
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Journal Articles

The Virtual Child

Richard J. Gilbertson, Sam Behjati, Anna-Lisa Böttcher, Marianne E. Bronner, Matthew Burridge, Henrick Clausing, Harry Clifford, Tracey Danaher, Laura K. Donovan, Jarno Drost, Alexander M.M. Eggermont, Chris Emerson, Mona G. Flores, Petra Hamerlik, Nada Jabado, Andrew Jones, Henrick Kaessmann, Claudia L. Kleinman, Marcel Kool, Lena M. Kutscher, Gavin Lindberg, Emily Linnane, John C. Marioni, John M. Maris, Michelle Monje, Alexandra Macaskill, Steven Niederer, Paul A. Northcott, Elizabeth Peeters, Willemijn Plieger-van Solkema, Liane Preußner, Anne C. Rios, Karsten Rippe, Peter Sandford, Nikolaos G. Sgourakis, Adam Shlien, Pete Smith, Karin Straathof, Patrick J. Sullivan, Mario L. Suvà, Michael D. Taylor, Emma Thompson, Roser Vento-Tormo, Brandon J. Wainwright, Robert J. Wechsler-Reya, Frank Westermann, Shannon Winslade, Bissan Al-Lazikani, Stefan M. Pfister
Journal: Cancer Discovery
Cancer Discov (2024) 14 (4): 663–668.
https://doi.org/10.1158/2159-8290.CD-23-1500
Published: 04 April 2024
View articletitled, The Virtual Child
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Journal Articles

A Summary of the Inaugural WHO Classification of Pediatric Tumors: Transitioning from the Optical into the Molecular Era

Stefan M. Pfister, Miguel Reyes-Múgica, John K.C. Chan, Henrik Hasle, Alexander J. Lazar, Sabrina Rossi, Andrea Ferrari, Jason A. Jarzembowski, Kathy Pritchard-Jones, D. Ashley Hill, Thomas S. Jacques, Pieter Wesseling, Dolores H. López Terrada, Andreas von Deimling, Christian P. Kratz, Ian A. Cree, Rita Alaggio
Journal: Cancer Discovery
Cancer Discov (2022) 12 (2): 331–355.
https://doi.org/10.1158/2159-8290.CD-21-1094
Published: 02 February 2022
View articletitled, A Summary of the Inaugural WHO Classification of Pediatric Tumors: Transitioning from the Optical into the Molecular Era
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Includes: Supplementary data
Journal Articles

The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

Cornelis M. van Tilburg, Elke Pfaff, Kristian W. Pajtler, Karin P.S. Langenberg, Petra Fiesel, Barbara C. Jones, Gnana Prakash Balasubramanian, Sebastian Stark, Pascal D. Johann, Mirjam Blattner-Johnson, Kathrin Schramm, Nicola Dikow, Steffen Hirsch, Christian Sutter, Kerstin Grund, Arend von Stackelberg, Andreas E. Kulozik, Andrej Lissat, Arndt Borkhardt, Roland Meisel, Dirk Reinhardt, Jan-Henning Klusmann, Gudrun Fleischhack, Stephan Tippelt, Dietrich von Schweinitz, Irene Schmid, Christof M. Kramm, André O. von Bueren, Gabriele Calaminus, Peter Vorwerk, Norbert Graf, Frank Westermann, Matthias Fischer, Angelika Eggert, Birgit Burkhardt, Wilhelm Wößmann, Michaela Nathrath, Stefanie Hecker-Nolting, Michael C. Frühwald, Dominik T. Schneider, Ines B. Brecht, Petra Ketteler, Simone Fulda, Ewa Koscielniak, Michael T. Meister, Monika Scheer, Simone Hettmer, Matthias Schwab, Roman Tremmel, Ingrid Øra, Caroline Hutter, Nicolas U. Gerber, Olli Lohi, Bernarda Kazanowska, Antonis Kattamis, Maria Filippidou, Bianca Goemans, C. Michel Zwaan, Till Milde, Natalie Jäger, Stephan Wolf, David Reuss, Felix Sahm, Andreas von Deimling, Uta Dirksen, Angelika Freitag, Ruth Witt, Peter Lichter, Annette Kopp-Schneider, David T.W. Jones, Jan J. Molenaar, David Capper, Stefan M. Pfister, Olaf Witt
Journal: Cancer Discovery
Cancer Discov (2021) 11 (11): 2764–2779.
https://doi.org/10.1158/2159-8290.CD-21-0094
Published: 01 November 2021
View articletitled, The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets
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Includes: Supplementary data
Journal Articles

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas

Tuyu Zheng, David R. Ghasemi, Konstantin Okonechnikov, Andrey Korshunov, Martin Sill, Kendra K. Maass, Patricia Benites Goncalves da Silva, Marina Ryzhova, Johannes Gojo, Damian Stichel, Amir Arabzade, Robert Kupp, Julia Benzel, Shinichiro Taya, Toma Adachi, Ryo Shiraishi, Nicolas U. Gerber, Dominik Sturm, Jonas Ecker, Philipp Sievers, Florian Selt, Rebecca Chapman, Christine Haberler, Dominique Figarella-Branger, Guido Reifenberger, Gudrun Fleischhack, Stefan Rutkowski, Andrew M. Donson, Vijay Ramaswamy, David Capper, David W. Ellison, Christel C. Herold-Mende, Ulrich Schüller, Sebastian Brandner, Pablo Hernáiz Driever, Johan M. Kros, Matija Snuderl, Till Milde, Richard G. Grundy, Mikio Hoshino, Stephen C. Mack, Richard J. Gilbertson, David T.W. Jones, Marcel Kool, Andreas von Deimling, Stefan M. Pfister, Felix Sahm, Daisuke Kawauchi, Kristian W. Pajtler
Journal: Cancer Discovery
Cancer Discov (2021) 11 (9): 2230–2247.
https://doi.org/10.1158/2159-8290.CD-20-0963
Published: 01 September 2021
View articletitled, Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas
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Includes: Supplementary data
Journal Articles

ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma

Amir Arabzade, Yanhua Zhao, Srinidhi Varadharajan, Hsiao-Chi Chen, Selin Jessa, Bryan Rivas, Austin J. Stuckert, Minerva Solis, Alisha Kardian, Dana Tlais, Brian J. Golbourn, Ann-Catherine J. Stanton, Yuen San Chan, Calla Olson, Kristen L. Karlin, Kathleen Kong, Robert Kupp, Baoli Hu, Sarah G. Injac, Madeline Ngo, Peter R. Wang, Luz A. De León, Felix Sahm, Daisuke Kawauchi, Stefan M. Pfister, Charles Y. Lin, H. Courtney Hodges, Irtisha Singh, Thomas F. Westbrook, Murali M. Chintagumpala, Susan M. Blaney, Donald W. Parsons, Kristian W. Pajtler, Sameer Agnihotri, Richard J. Gilbertson, Joanna Yi, Nada Jabado, Claudia L. Kleinman, Kelsey C. Bertrand, Benjamin Deneen, Stephen C. Mack
Journal: Cancer Discovery
Cancer Discov (2021) 11 (9): 2200–2215.
https://doi.org/10.1158/2159-8290.CD-20-1066
Published: 01 September 2021
View articletitled, ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
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Includes: Supplementary data
Journal Articles

ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors

Robert Kupp, Lisa Ruff, Sabrina Terranova, Erica Nathan, Stephane Ballereau, Rory Stark, Chandra Sekhar Reddy Chilamakuri, Nadin Hoffmann, Katherine Wickham-Rahrmann, Marcus Widdess, Amir Arabzade, Yanhua Zhao, Srinidhi Varadharajan, Tuyu Zheng, Mohankumar Murugesan, Stefan M. Pfister, Daisuke Kawauchi, Kristian W. Pajtler, Benjamin Deneen, Stephen C. Mack, Katherine E. Masih, Berkley E. Gryder, Javed Khan, Richard J. Gilbertson
Journal: Cancer Discovery
Cancer Discov (2021) 11 (9): 2216–2229.
https://doi.org/10.1158/2159-8290.CD-20-1052
Published: 01 September 2021
View articletitled, ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors
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Includes: Supplementary data
Journal Articles

Maturation Block in Childhood Cancer

Sam Behjati, Richard J. Gilbertson, Stefan M. Pfister
Journal: Cancer Discovery
Cancer Discov (2021) 11 (3): 542–544.
https://doi.org/10.1158/2159-8290.CD-20-0926
Published: 02 March 2021
View articletitled, Maturation Block in Childhood Cancer
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Journal Articles

Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes

Matthew Clarke, Alan Mackay, Britta Ismer, Jessica C. Pickles, Ruth G. Tatevossian, Scott Newman, Tejus A. Bale, Iris Stoler, Elisa Izquierdo, Sara Temelso, Diana M. Carvalho, Valeria Molinari, Anna Burford, Louise Howell, Alex Virasami, Amy R. Fairchild, Aimee Avery, Jane Chalker, Mark Kristiansen, Kelly Haupfear, James D. Dalton, Wilda Orisme, Ji Wen, Michael Hubank, Kathreena M. Kurian, Catherine Rowe, Mellissa Maybury, Stephen Crosier, Jeffrey Knipstein, Ulrich Schüller, Uwe Kordes, David E. Kram, Matija Snuderl, Leslie Bridges, Andrew J. Martin, Lawrence J. Doey, Safa Al-Sarraj, Christopher Chandler, Bassel Zebian, Claire Cairns, Rachael Natrajan, Jessica K.R. Boult, Simon P. Robinson, Martin Sill, Ira J. Dunkel, Stephen W. Gilheeney, Marc K. Rosenblum, Debbie Hughes, Paula Z. Proszek, Tobey J. Macdonald, Matthias Preusser, Christine Haberler, Irene Slavc, Roger Packer, Ho-Keung Ng, Shani Caspi, Mara Popović, Barbara Faganel Kotnik, Matthew D. Wood, Lissa Baird, Monika Ashok Davare, David A. Solomon, Thale Kristin Olsen, Petter Brandal, Michael Farrell, Jane B. Cryan, Michael Capra, Michael Karremann, Jens Schittenhelm, Martin U. Schuhmann, Martin Ebinger, Winand N.M. Dinjens, Kornelius Kerl, Simone Hettmer, Torsten Pietsch, Felipe Andreiuolo, Pablo Hernáiz Driever, Andrey Korshunov, Lotte Hiddingh, Barbara C. Worst, Dominik Sturm, Marc Zuckermann, Olaf Witt, Tabitha Bloom, Clare Mitchell, Evelina Miele, Giovanna Stefania Colafati, Francesca Diomedi-Camassei, Simon Bailey, Andrew S. Moore, Timothy E.G. Hassall, Stephen P. Lowis, Maria Tsoli, Mark J. Cowley, David S. Ziegler, Matthias A. Karajannis, Kristian Aquilina, Darren R. Hargrave, Fernando Carceller, Lynley V. Marshall, Andreas von Deimling, Christof M. Kramm, Stefan M. Pfister, Felix Sahm, Suzanne J. Baker, Angela Mastronuzzi, Andrea Carai, Maria Vinci, David Capper, Sergey Popov, David W. Ellison, Thomas S. Jacques, David T.W. Jones, Chris Jones
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (7): 942–963.
https://doi.org/10.1158/2159-8290.CD-19-1030
Published: 01 July 2020
View articletitled, Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes
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Includes: Supplementary data