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Shunbin Xiong
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Journal Articles

Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small Molecule Reactivator

Anna M. Puzio-Kuter, Lizhong Xu, Mary Kate McBrayer, Romyr Dominique, Hongju H. Li, Bruce J. Fahr, Alyssa M. Brown, Amy E. Wiebesiek, Brandon M. Russo, Chris L. Mulligan, Hong Yang, Josh Battaglia, Kimberly A. Robell, Dafydd H. Thomas, Kuo-Sen Huang, Alexander Solovyov, Benjamin D. Greenbaum, Jonathan D. Oliner, Thomas W. Davis, Melissa L. Dumble, Melissa L. Johnson, Shunbin Xiong, Peirong Yang, Guillermina Lozano, Marc M. Fellous, Binh T. Vu, Alison M. Schram, Arnold J. Levine, Masha V. Poyurovsky
Journal: Cancer Discovery
Cancer Discov (2025)
https://doi.org/10.1158/2159-8290.CD-24-1421
Published: 14 February 2025
View articletitled, Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small Molecule Reactivator
Open the PDF for Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small Molecule Reactivator in another window
Includes: Supplementary data
Journal Articles

Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program

Jovanka Gencel-Augusto, Xiaoping Su, Yuan Qi, Elizabeth M. Whitley, Vinod Pant, Shunbin Xiong, Vrutant Shah, Jerome Lin, Encarnacion Perez, Marta L. Fiorotto, Iqbal Mahmud, Abhinav K. Jain, Philip L. Lorenzi, Nicholas E. Navin, Ellen R. Richie, Guillermina Lozano
Journal: Cancer Discovery
Cancer Discov (2023) 13 (5): 1230–1249.
https://doi.org/10.1158/2159-8290.CD-22-0872
Published: 04 May 2023
View articletitled, Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program
Open the PDF for Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program in another window
Includes: Supplementary data
Journal Articles

Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis

Michael P. Kim, Xinqun Li, Jenying Deng, Yun Zhang, Bingbing Dai, Kendra L. Allton, Tara G. Hughes, Christian Siangco, Jithesh J. Augustine, Ya'an Kang, Joy M. McDaniel, Shunbin Xiong, Eugene J. Koay, Florencia McAllister, Christopher A. Bristow, Timothy P. Heffernan, Anirban Maitra, Bin Liu, Michelle C. Barton, Amanda R. Wasylishen, Jason B. Fleming, Guillermina Lozano
Journal: Cancer Discovery
Cancer Discov (2021) 11 (8): 2094–2111.
https://doi.org/10.1158/2159-8290.CD-20-1228
Published: 01 August 2021
View articletitled, Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis
Open the PDF for Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis in another window
Includes: Supplementary data