1-4 of 4
Shiva Malek
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy

Open Access
Kyung W. Song, Kyle A. Edgar, Emily J. Hanan, Marc Hafner, Jason Oeh, Mark Merchant, Deepak Sampath, Michelle A. Nannini, Rebecca Hong, Lilian Phu, William F. Forrest, Eric Stawiski, Stephen Schmidt, Nicholas Endres, Jane Guan, Jeffrey J. Wallin, Jonathan Cheong, Emile G. Plise, Gail D. Lewis Phillips, Laurent Salphati, Timothy P. Heffron, Alan G. Olivero, Shiva Malek, Steven T. Staben, Donald S. Kirkpatrick, Anwesha Dey, Lori S. Friedman
Journal: Cancer Discovery
Cancer Discov (2022) 12 (1): 204–219.
https://doi.org/10.1158/2159-8290.CD-21-0072
Published: 01 January 2022
View articletitled, RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy
Open the PDF for RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy in another window
Includes: Supplementary data
Journal Articles

Emerging Trends in Cancer Drug Discovery—From Drugging the “Undruggable” to Overcoming Resistance

Available to Purchase
Joachim Rudolph, Jeff Settleman, Shiva Malek
Journal: Cancer Discovery
Cancer Discov (2021) 11 (4): 815–821.
https://doi.org/10.1158/2159-8290.CD-21-0260
Published: 01 April 2021
View articletitled, Emerging Trends in Cancer Drug Discovery—From Drugging the “Undruggable” to Overcoming Resistance
Open the PDF for Emerging Trends in Cancer Drug Discovery—From Drugging the “Undruggable” to Overcoming Resistance in another window
Journal Articles

Machine-Learning and Chemicogenomics Approach Defines and Predicts Cross-Talk of Hippo and MAPK Pathways

Free
Trang H. Pham, Thijs J. Hagenbeek, Ho-June Lee, Jason Li, Christopher M. Rose, Eva Lin, Mamie Yu, Scott E. Martin, Robert Piskol, Jennifer A. Lacap, Deepak Sampath, Victoria C. Pham, Zora Modrusan, Jennie R. Lill, Christiaan Klijn, Shiva Malek, Matthew T. Chang, Anwesha Dey
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (3): 778–793.
https://doi.org/10.1158/2159-8290.CD-20-0706
Published: 02 March 2021
View articletitled, Machine-Learning and Chemicogenomics Approach Defines and Predicts Cross-Talk of Hippo and MAPK Pathways
Open the PDF for Machine-Learning and Chemicogenomics Approach Defines and Predicts Cross-Talk of Hippo and MAPK Pathways in another window
Includes: Supplementary data
Journal Articles

Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M

Free
Ho-June Lee, Gabriele Schaefer, Timothy P. Heffron, Lily Shao, Xiaofen Ye, Steve Sideris, Shiva Malek, Emily Chan, Mark Merchant, Hank La, Savita Ubhayakar, Robert L. Yauch, Valentina Pirazzoli, Katerina Politi, Jeff Settleman
Journal: Cancer Discovery
Cancer Discov (2013) 3 (2): 168–181.
https://doi.org/10.1158/2159-8290.CD-12-0357
Published: 10 February 2013
View articletitled, Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M
Open the PDF for Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M in another window
Includes: Supplementary data