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Sharmeen Uddin
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Journal Articles

A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAFV600E-Mutant Brain Tumor

Jiawan Wang, Zhan Yao, Philip Jonsson, Amy N. Allen, Alice Can Ran Qin, Sharmeen Uddin, Ira J. Dunkel, Mary Petriccione, Katia Manova, Sofia Haque, Marc K. Rosenblum, David J. Pisapia, Neal Rosen, Barry S. Taylor, Christine A. Pratilas
Journal: Cancer Discovery
Cancer Discov (2018) 8 (9): 1130–1141.
https://doi.org/10.1158/2159-8290.CD-17-1263
Published: 04 September 2018
View article titled, A Secondary Mutation in <em>BRAF</em> Confers Resistance to RAF Inhibition in a <em>BRAF</em><sup>V600E</sup>-Mutant Brain Tumor
Open the PDF for A Secondary Mutation in <em>BRAF</em> Confers Resistance to RAF Inhibition in a <em>BRAF</em><sup>V600E</sup>-Mutant Brain Tumor in another window
Includes: Supplementary data
Journal Articles

Activating ESR1 Mutations Differentially Affect the Efficacy of ER Antagonists

Weiyi Toy, Hazel Weir, Pedram Razavi, Mandy Lawson, Anne U. Goeppert, Anne Marie Mazzola, Aaron Smith, Joanne Wilson, Christopher Morrow, Wai Lin Wong, Elisa De Stanchina, Kathryn E. Carlson, Teresa S. Martin, Sharmeen Uddin, Zhiqiang Li, Sean Fanning, John A. Katzenellenbogen, Geoffrey Greene, José Baselga, Sarat Chandarlapaty
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (3): 277–287.
https://doi.org/10.1158/2159-8290.CD-15-1523
Published: 05 March 2017
View article titled, Activating <em>ESR1</em> Mutations Differentially Affect the Efficacy of ER Antagonists
Open the PDF for Activating <em>ESR1</em> Mutations Differentially Affect the Efficacy of ER Antagonists in another window
Includes: Supplementary data
Journal Articles

Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in EGFR-Mutant Lung Cancer

Erin M. Tricker, Chunxiao Xu, Sharmeen Uddin, Marzia Capelletti, Dalia Ercan, Atsuko Ogino, Christine A. Pratilas, Neal Rosen, Nathanael S. Gray, Kwok-Kin Wong, Pasi A. Jänne
Journal: Cancer Discovery
Cancer Discov (2015) 5 (9): 960–971.
https://doi.org/10.1158/2159-8290.CD-15-0063
Published: 01 September 2015
View article titled, Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in <em>EGFR</em>-Mutant Lung Cancer
Open the PDF for Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in <em>EGFR</em>-Mutant Lung Cancer in another window
Includes: Supplementary data