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Sandra Misale
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Journal Articles

The Far Side of Resistance to RAS Inhibitors

Michelangelo Marasco, Sandra Misale
Journal: Cancer Discovery
Cancer Discov (2024) 14 (11): 2018–2020.
https://doi.org/10.1158/2159-8290.CD-24-1153
Published: 01 November 2024
View article titled, The Far Side of Resistance to RAS Inhibitors
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Journal Articles

RAS G12C Inhibitors: Three Birds with One Stone

Tessa Seale, Sandra Misale
Journal: Cancer Discovery
Cancer Discov (2024) 14 (5): 698–700.
https://doi.org/10.1158/2159-8290.CD-24-0175
Published: 01 May 2024
View article titled, RAS G12C Inhibitors: Three Birds with One Stone
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Journal Articles

Molecular Characterization of Acquired Resistance to KRASG12C–EGFR Inhibition in Colorectal Cancer

Rona Yaeger, Riccardo Mezzadra, Jenna Sinopoli, Yu Bian, Michelangelo Marasco, Esther Kaplun, Yijun Gao, HuiYong Zhao, Arnaud Da Cruz Paula, Yingjie Zhu, Almudena Chaves Perez, Kalyani Chadalavada, Edison Tse, Sudhir Chowdhry, Sydney Bowker, Qing Chang, Besnik Qeriqi, Britta Weigelt, Gouri J. Nanjangud, Michael F. Berger, Hirak Der-Torossian, Kenna Anderes, Nicholas D. Socci, Jinru Shia, Gregory J. Riely, Yonina R. Murciano-Goroff, Bob T. Li, James G. Christensen, Jorge S. Reis-Filho, David B. Solit, Elisa de Stanchina, Scott W. Lowe, Neal Rosen, Sandra Misale
Journal: Cancer Discovery
Cancer Discov (2023) 13 (1): 41–55.
https://doi.org/10.1158/2159-8290.CD-22-0405
Published: 09 January 2023
View article titled, Molecular Characterization of Acquired Resistance to KRAS<sup>G12C</sup>–EGFR Inhibition in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Expanding the Reach of Precision Oncology by Drugging All KRAS Mutants

Marco H. Hofmann, Daniel Gerlach, Sandra Misale, Mark Petronczki, Norbert Kraut
Journal: Cancer Discovery
Cancer Discov (2022) 12 (4): 924–937.
https://doi.org/10.1158/2159-8290.CD-21-1331
Published: 01 April 2022
View article titled, Expanding the Reach of Precision Oncology by Drugging All <em>KRAS</em> Mutants
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Includes: Supplementary data
Journal Articles

TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors

Emiliano Cocco, Ji Eun Lee, Srinivasaraghavan Kannan, Alison M. Schram, Helen H. Won, Sophie Shifman, Amanda Kulick, Laura Baldino, Eneda Toska, Amaia Arruabarrena-Aristorena, Srushti Kittane, Fan Wu, Yanyan Cai, Sabrina Arena, Benedetta Mussolin, Ram Kannan, Neil Vasan, Alexander N. Gorelick, Michael F. Berger, Ofra Novoplansky, Sankar Jagadeeshan, Yi Liao, Uwe Rix, Sandra Misale, Barry S. Taylor, Alberto Bardelli, Jaclyn F. Hechtman, David M. Hyman, Moshe Elkabets, Elisa de Stanchina, Chandra S. Verma, Andrea Ventura, Alexander Drilon, Maurizio Scaltriti
Journal: Cancer Discovery
Cancer Discov (2021) 11 (1): 126–141.
https://doi.org/10.1158/2159-8290.CD-20-0571
Published: 06 January 2021
View article titled, TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors
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Includes: Supplementary data
Journal Articles

EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer

Vito Amodio, Rona Yaeger, Pamela Arcella, Carlotta Cancelliere, Simona Lamba, Annalisa Lorenzato, Sabrina Arena, Monica Montone, Benedetta Mussolin, Yu Bian, Adele Whaley, Marika Pinnelli, Yonina R. Murciano-Goroff, Efsevia Vakiani, Nicola Valeri, Wei-Li Liao, Anuja Bhalkikar, Sheeno Thyparambil, Hui-Yong Zhao, Elisa de Stanchina, Silvia Marsoni, Salvatore Siena, Andrea Bertotti, Livio Trusolino, Bob T. Li, Neal Rosen, Federica Di Nicolantonio, Alberto Bardelli, Sandra Misale
Journal: Cancer Discovery
Cancer Discov (2020) 10 (8): 1129–1139.
https://doi.org/10.1158/2159-8290.CD-20-0187
Published: 03 August 2020
View article titled, EGFR Blockade Reverts Resistance to KRAS<sup>G12C</sup> Inhibition in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers

Bob T. Li, Flavia Michelini, Sandra Misale, Emiliano Cocco, Laura Baldino, Yanyan Cai, Sophie Shifman, Hai-Yan Tu, Mackenzie L. Myers, Chongrui Xu, Marissa Mattar, Inna Khodos, Megan Little, Besnik Qeriqi, Gregory Weitsman, Clare J. Wilhem, Alshad S. Lalani, Irmina Diala, Rachel A. Freedman, Nancy U. Lin, David B. Solit, Michael F. Berger, Paul R. Barber, Tony Ng, Michael Offin, James M. Isbell, David R. Jones, Helena A. Yu, Sheeno Thyparambil, Wei-Li Liao, Anuja Bhalkikar, Fabiola Cecchi, David M. Hyman, Jason S. Lewis, Darren J. Buonocore, Alan L. Ho, Vicky Makker, Jorge S. Reis-Filho, Pedram Razavi, Maria E. Arcila, Mark G. Kris, John T. Poirier, Ronglai Shen, Junji Tsurutani, Gary A. Ulaner, Elisa de Stanchina, Neal Rosen, Charles M. Rudin, Maurizio Scaltriti
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (5): 674–687.
https://doi.org/10.1158/2159-8290.CD-20-0215
Published: 01 May 2020
View article titled, HER2-Mediated Internalization of Cytotoxic Agents in <em>ERBB2</em> Amplified or Mutant Lung Cancers
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Includes: Supplementary data
Journal Articles

Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer

Mariangela Russo, Sandra Misale, Ge Wei, Giulia Siravegna, Giovanni Crisafulli, Luca Lazzari, Giorgio Corti, Giuseppe Rospo, Luca Novara, Benedetta Mussolin, Alice Bartolini, Nicholas Cam, Roopal Patel, Shunqi Yan, Robert Shoemaker, Robert Wild, Federica Di Nicolantonio, Andrea Sartore Bianchi, Gang Li, Salvatore Siena, Alberto Bardelli
Journal: Cancer Discovery
Cancer Discov (2016) 6 (1): 36–44.
https://doi.org/10.1158/2159-8290.CD-15-0940
Published: 07 January 2016
View article titled, Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Resistance to Anti-EGFR Therapy in Colorectal Cancer: From Heterogeneity to Convergent Evolution

Sandra Misale, Federica Di Nicolantonio, Andrea Sartore-Bianchi, Salvatore Siena, Alberto Bardelli
Journal: Cancer Discovery
Cancer Discov (2014) 4 (11): 1269–1280.
https://doi.org/10.1158/2159-8290.CD-14-0462
Published: 01 November 2014
View article titled, Resistance to Anti-EGFR Therapy in Colorectal Cancer: From Heterogeneity to Convergent Evolution
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