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Samuel F. Bakhoum
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Journal Articles

Targeting RNA and Protein Turnover in Aneuploid Cancers

Samuel F. Bakhoum
Journal: Cancer Discovery
Cancer Discov (2024) 14 (12): 2315–2316.
https://doi.org/10.1158/2159-8290.CD-24-1350
Published: 02 December 2024
View article titled, Targeting RNA and Protein Turnover in Aneuploid Cancers
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Journal Articles

Micronuclei and Cancer

Melody Di Bona, Samuel F. Bakhoum
Journal: Cancer Discovery
Cancer Discov (2024) 14 (2): 214–226.
https://doi.org/10.1158/2159-8290.CD-23-1073
Published: 08 February 2024
View article titled, Micronuclei and Cancer
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Journal Articles

Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution

Subramanian Venkatesan, Mihaela Angelova, Clare Puttick, Haoran Zhai, Deborah R. Caswell, Wei-Ting Lu, Michelle Dietzen, Panagiotis Galanos, Konstantinos Evangelou, Roberto Bellelli, Emilia L. Lim, Thomas B.K. Watkins, Andrew Rowan, Vitor H. Teixeira, Yue Zhao, Haiquan Chen, Bryan Ngo, Lykourgos-Panagiotis Zalmas, Maise Al Bakir, Sebastijan Hobor, Eva Grönroos, Adam Pennycuick, Ersilia Nigro, Brittany B. Campbell, William L. Brown, Ayse U. Akarca, Teresa Marafioti, Mary Y. Wu, Michael Howell, Simon J. Boulton, Cosetta Bertoli, Tim R. Fenton, Robertus A.M. de Bruin, Apolinar Maya-Mendoza, Eric Santoni-Rugiu, Robert E. Hynds, Vassilis G. Gorgoulis, Mariam Jamal-Hanjani, Nicholas McGranahan, Reuben S. Harris, Sam M. Janes, Jirina Bartkova, Samuel F. Bakhoum, Jiri Bartek, Nnennaya Kanu, Charles Swanton
Journal: Cancer Discovery
Cancer Discov (2021) 11 (10): 2456–2473.
https://doi.org/10.1158/2159-8290.CD-20-0725
Published: 01 October 2021
View article titled, Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution
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Includes: Supplementary data
Journal Articles

Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis

Jun Li, Mercedes A. Duran, Ninjit Dhanota, Walid K. Chatila, Sarah E. Bettigole, John Kwon, Roshan K. Sriram, Matthew P. Humphries, Manuel Salto-Tellez, Jacqueline A. James, Matthew G. Hanna, Johannes C. Melms, Sreeram Vallabhaneni, Kevin Litchfield, Ieva Usaite, Dhruva Biswas, Rohan Bareja, Hao Wei Li, Maria Laura Martin, Princesca Dorsaint, Julie-Ann Cavallo, Peng Li, Chantal Pauli, Lee Gottesdiener, Benjamin J. DiPardo, Travis J. Hollmann, Taha Merghoub, Hannah Y. Wen, Jorge S. Reis-Filho, Nadeem Riaz, Shin-San Michael Su, Anusha Kalbasi, Neil Vasan, Simon N. Powell, Jedd D. Wolchok, Olivier Elemento, Charles Swanton, Alexander N. Shoushtari, Eileen E. Parkes, Benjamin Izar, Samuel F. Bakhoum
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (5): 1212–1227.
https://doi.org/10.1158/2159-8290.CD-20-0387
Published: 01 May 2021
View article titled, Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis
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Includes: Supplementary data
Journal Articles

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

Bryan Ngo, Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Roger J. Liang, Alba Luengo, Shawn M. Davidson, Ahmed Ali, Gino B. Ferraro, Grant M. Fischer, Roozbeh Eskandari, Diane S. Kang, Jing Ni, Ariana Plasger, Vinagolu K. Rajasekhar, Edward R. Kastenhuber, Sarah Bacha, Roshan K. Sriram, Benjamin D. Stein, Samuel F. Bakhoum, Matija Snuderl, Paolo Cotzia, John H. Healey, Nello Mainolfi, Vipin Suri, Adam Friedman, Mark Manfredi, David M. Sabatini, Drew R. Jones, Min Yu, Jean J. Zhao, Rakesh K. Jain, Kayvan R. Keshari, Michael A. Davies, Matthew G. Vander Heiden, Eva Hernando, Matthias Mann, Lewis C. Cantley, Michael E. Pacold
Journal: Cancer Discovery
Cancer Discov (2020) 10 (9): 1352–1373.
https://doi.org/10.1158/2159-8290.CD-19-1228
Published: 01 September 2020
View article titled, Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition
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Includes: Supplementary data
Journal Articles

The Cytosolic DNA-Sensing cGAS–STING Pathway in Cancer

John Kwon, Samuel F. Bakhoum
Journal: Cancer Discovery
Cancer Discov (2020) 10 (1): 26–39.
https://doi.org/10.1158/2159-8290.CD-19-0761
Published: 09 January 2020
View article titled, The Cytosolic DNA-Sensing cGAS–STING Pathway in Cancer
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Journal Articles

DNA-Damage Response during Mitosis Induces Whole-Chromosome Missegregation

Samuel F. Bakhoum, Lilian Kabeche, John P. Murnane, Bassem I. Zaki, Duane A. Compton
Journal: Cancer Discovery
Cancer Discov (2014) 4 (11): 1281–1289.
https://doi.org/10.1158/2159-8290.CD-14-0403
Published: 01 November 2014
View article titled, DNA-Damage Response during Mitosis Induces Whole-Chromosome Missegregation
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Includes: Supplementary data