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Sacha Gnjatic
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Journal Articles

PGV001, a multi-peptide personalized neoantigen vaccine platform: Phase I study in patients with solid and hematological malignancies in the adjuvant setting

Mansi Saxena, Thomas U. Marron, Julia Kodysh, John P. Finnigan, Sayali Onkar, Anna Kaminska, Kevin Tuballes, Ruiwei Guo, Rachel Lubong. Sabado, Marcia Meseck, Timothy J. O'Donnell, Robert P. Sebra, Samir Parekh, Matthew D. Galsky, Ana Blasquez, Gustavo Gimenez, Mesude Bicak, Cansu Cimen Bozkus, Daniela Delbeau-Zagelbaum, Denise Rodriguez, Ana Acuna-Villaorduna, Krzysztof J. Misiukiewicz, Marshall R. Posner, Brett A. Miles, Hanna Y. Irie, Amy Tiersten, Deborah B. Doroshow, Andrea Wolf, John Mandeli, Rachel Brody, Andres M. Salazar, Sacha Gnjatic, Jeff Hammerbacher, Eric Schadt, Philip Friedlander, Alexander Rubinsteyn, Nina Bhardwaj
Journal: Cancer Discovery
Cancer Discov (2025)
https://doi.org/10.1158/2159-8290.CD-24-0934
Published: 17 March 2025
View article titled, PGV001, a multi-peptide personalized neoantigen vaccine platform: Phase I study in patients with solid and hematological malignancies in the adjuvant setting
Open the PDF for PGV001, a multi-peptide personalized neoantigen vaccine platform: Phase I study in patients with solid and hematological malignancies in the adjuvant setting in another window
Includes: Supplementary data
Journal Articles

Single-Cell View of Tumor Microenvironment Gradients in Pleural Mesothelioma

Bruno Giotti, Komal Dolasia, William Zhao, Peiwen Cai, Robert Sweeney, Elliot Merritt, Evgeny Kiner, Grace S. Kim, Atharva Bhagwat, Thinh Nguyen, Samarth Hegde, Bailey G. Fitzgerald, Sanjana Shroff, Travis Dawson, Monica Garcia-Barros, Jamshid Abdul-Ghafar, Rachel Chen, Sacha Gnjatic, Alan Soto, Rachel Brody, Seunghee Kim-Schulze, Zhihong Chen, Kristin G. Beaumont, Miriam Merad, Raja M. Flores, Robert P. Sebra, Amir Horowitz, Thomas U. Marron, Anna Tocheva, Andrea Wolf, Alexander M. Tsankov
Journal: Cancer Discovery
Cancer Discov (2024) 14 (11): 2262–2278.
https://doi.org/10.1158/2159-8290.CD-23-0017
Published: 01 November 2024
View article titled, Single-Cell View of Tumor Microenvironment Gradients in Pleural Mesothelioma
Open the PDF for Single-Cell View of Tumor Microenvironment Gradients in Pleural Mesothelioma in another window
Includes: Supplementary data
Journal Articles

Spatial Positioning and Matrix Programs of Cancer-Associated Fibroblasts Promote T-cell Exclusion in Human Lung Tumors

John A. Grout, Philemon Sirven, Andrew M. Leader, Shrisha Maskey, Eglantine Hector, Isabelle Puisieux, Fiona Steffan, Evan Cheng, Navpreet Tung, Mathieu Maurin, Romain Vaineau, Lea Karpf, Martin Plaud, Anne-Laure Begue, Koushik Ganesh, Jérémy Mesple, Maria Casanova-Acebes, Alexandra Tabachnikova, Shilpa Keerthivasan, Alona Lansky, Jessica Le Berichel, Laura Walker, Adeeb H. Rahman, Sacha Gnjatic, Nicolas Girard, Marine Lefevre, Diane Damotte, Julien Adam, Jerome C. Martin, Andrea Wolf, Raja M. Flores, Mary Beth Beasley, Rachana Pradhan, Soren Muller, Thomas U. Marron, Shannon J. Turley, Miriam Merad, Ephraim Kenigsberg, Hélène Salmon
Journal: Cancer Discovery
Cancer Discov (2022) 12 (11): 2606–2625.
https://doi.org/10.1158/2159-8290.CD-21-1714
Published: 02 November 2022
View article titled, Spatial Positioning and Matrix Programs of Cancer-Associated Fibroblasts Promote T-cell Exclusion in Human Lung Tumors
Open the PDF for Spatial Positioning and Matrix Programs of Cancer-Associated Fibroblasts Promote T-cell Exclusion in Human Lung Tumors in another window
Includes: Supplementary data