1-10 of 10
Sabina Signoretti
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival

Matthew G. Oser, Raquel Fonseca, Abhishek A. Chakraborty, Rachel Brough, Alexander Spektor, Rebecca B. Jennings, Abdallah Flaifel, Jesse S. Novak, Aditi Gulati, Elizabeth Buss, Scott T. Younger, Samuel K. McBrayer, Glenn S. Cowley, Dennis M. Bonal, Quang-De Nguyen, Laura Brulle-Soumare, Paula Taylor, Stefano Cairo, Colm J. Ryan, Elizabeth J. Pease, Kim Maratea, Jon Travers, David E. Root, Sabina Signoretti, David Pellman, Susan Ashton, Christopher J. Lord, Simon T. Barry, William G. Kaelin, Jr
Journal: Cancer Discovery
Cancer Discov (2019) 9 (2): 230–247.
https://doi.org/10.1158/2159-8290.CD-18-0389
Published: 08 February 2019
View article titled, Cells Lacking the <em>RB1</em> Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival
Open the PDF for Cells Lacking the <em>RB1</em> Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival in another window
Includes: Supplementary data
Journal Articles

Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity

Akash Patnaik, Kenneth D. Swanson, Eva Csizmadia, Aniruddh Solanki, Natalie Landon-Brace, Marina P. Gehring, Katja Helenius, Brian M. Olson, Athalia R. Pyzer, Lily C. Wang, Olivier Elemento, Jesse Novak, Thomas B. Thornley, John M. Asara, Laleh Montaser, Joshua J. Timmons, Todd M. Morgan, Yugang Wang, Elena Levantini, John G. Clohessy, Kathleen Kelly, Pier Paolo Pandolfi, Jacalyn M. Rosenblatt, David E. Avigan, Huihui Ye, Jeffrey M. Karp, Sabina Signoretti, Steven P. Balk, Lewis C. Cantley
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (7): 750–765.
https://doi.org/10.1158/2159-8290.CD-16-0778
Published: 05 July 2017
View article titled, Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity
Open the PDF for Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity in another window
Includes: Supplementary data
Journal Articles

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

Priscilla K. Brastianos, Scott L. Carter, Sandro Santagata, Daniel P. Cahill, Amaro Taylor-Weiner, Robert T. Jones, Eliezer M. Van Allen, Michael S. Lawrence, Peleg M. Horowitz, Kristian Cibulskis, Keith L. Ligon, Josep Tabernero, Joan Seoane, Elena Martinez-Saez, William T. Curry, Ian F. Dunn, Sun Ha Paek, Sung-Hye Park, Aaron McKenna, Aaron Chevalier, Mara Rosenberg, Frederick G. Barker, II, Corey M. Gill, Paul Van Hummelen, Aaron R. Thorner, Bruce E. Johnson, Mai P. Hoang, Toni K. Choueiri, Sabina Signoretti, Carrie Sougnez, Michael S. Rabin, Nancy U. Lin, Eric P. Winer, Anat Stemmer-Rachamimov, Matthew Meyerson, Levi Garraway, Stacey Gabriel, Eric S. Lander, Rameen Beroukhim, Tracy T. Batchelor, José Baselga, David N. Louis, Gad Getz, William C. Hahn
Journal: Cancer Discovery
Cancer Discov (2015) 5 (11): 1164–1177.
https://doi.org/10.1158/2159-8290.CD-15-0369
Published: 01 November 2015
View article titled, Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
Open the PDF for Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets in another window
Includes: Supplementary data
Journal Articles

Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis

Andrea Lunardi, Shohreh Varmeh, Ming Chen, Riccardo Taulli, Jlenia Guarnerio, Ugo Ala, Nina Seitzer, Tomoki Ishikawa, Brett S. Carver, Robin M. Hobbs, Valentina Quarantotti, Christopher Ng, Alice H. Berger, Caterina Nardella, Laura Poliseno, Rodolfo Montironi, Mireia Castillo-Martin, Carlos Cordon-Cardo, Sabina Signoretti, Pier Paolo Pandolfi
Journal: Cancer Discovery
Cancer Discov (2015) 5 (5): 550–563.
https://doi.org/10.1158/2159-8290.CD-13-1050
Published: 03 May 2015
View article titled, Suppression of <em>CHK1</em> by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis
Open the PDF for Suppression of <em>CHK1</em> by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Somatic ERCC2 Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma

Eliezer M. Van Allen, Kent W. Mouw, Philip Kim, Gopa Iyer, Nikhil Wagle, Hikmat Al-Ahmadie, Cong Zhu, Irina Ostrovnaya, Gregory V. Kryukov, Kevin W. O'Connor, John Sfakianos, Ilana Garcia-Grossman, Jaegil Kim, Elizabeth A. Guancial, Richard Bambury, Samira Bahl, Namrata Gupta, Deborah Farlow, Angela Qu, Sabina Signoretti, Justine A. Barletta, Victor Reuter, Jesse Boehm, Michael Lawrence, Gad Getz, Philip Kantoff, Bernard H. Bochner, Toni K. Choueiri, Dean F. Bajorin, David B. Solit, Stacey Gabriel, Alan D'Andrea, Levi A. Garraway, Jonathan E. Rosenberg
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2014) 4 (10): 1140–1153.
https://doi.org/10.1158/2159-8290.CD-14-0623
Published: 30 September 2014
View article titled, Somatic <em>ERCC2</em> Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma
Open the PDF for Somatic <em>ERCC2</em> Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma in another window
Includes: Supplementary data
Journal Articles

Vulnerabilities of PTEN–TP53-Deficient Prostate Cancers to Compound PARP–PI3K Inhibition

Enrique González-Billalabeitia, Nina Seitzer, Su Jung Song, Min Sup Song, Akash Patnaik, Xue-Song Liu, Mirjam T. Epping, Antonella Papa, Robin M. Hobbs, Ming Chen, Andrea Lunardi, Christopher Ng, Kaitlyn A. Webster, Sabina Signoretti, Massimo Loda, John M. Asara, Caterina Nardella, John G. Clohessy, Lewis C. Cantley, Pier Paolo Pandolfi
Journal: Cancer Discovery
Cancer Discov (2014) 4 (8): 896–904.
https://doi.org/10.1158/2159-8290.CD-13-0230
Published: 03 August 2014
View article titled, Vulnerabilities of <em>PTEN</em>–<em>TP53</em>-Deficient Prostate Cancers to Compound PARP–PI3K Inhibition
Open the PDF for Vulnerabilities of <em>PTEN</em>–<em>TP53</em>-Deficient Prostate Cancers to Compound PARP–PI3K Inhibition in another window
Includes: Supplementary data
Journal Articles

Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib

Nikhil Wagle, Brian C. Grabiner, Eliezer M. Van Allen, Eran Hodis, Susanna Jacobus, Jeffrey G. Supko, Michelle Stewart, Toni K. Choueiri, Leena Gandhi, James M. Cleary, Aymen A. Elfiky, Mary Ellen Taplin, Edward C. Stack, Sabina Signoretti, Massimo Loda, Geoffrey I. Shapiro, David M. Sabatini, Eric S. Lander, Stacey B. Gabriel, Philip W. Kantoff, Levi A. Garraway, Jonathan E. Rosenberg
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2014) 4 (5): 546–553.
https://doi.org/10.1158/2159-8290.CD-13-0353
Published: 01 May 2014
View article titled, Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib
Open the PDF for Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib in another window
Includes: Supplementary data
Journal Articles

Opposing Effects of Androgen Deprivation and Targeted Therapy on Prostate Cancer Prevention

Shidong Jia, Xueliang Gao, Sang Hyun Lee, Sauveur-Michel Maira, Xiaoqiu Wu, Edward C. Stack, Sabina Signoretti, Massimo Loda, Jean J. Zhao, Thomas M. Roberts
Journal: Cancer Discovery
Cancer Discov (2013) 3 (1): 44–51.
https://doi.org/10.1158/2159-8290.CD-12-0262
Published: 13 January 2013
View article titled, Opposing Effects of Androgen Deprivation and Targeted Therapy on Prostate Cancer Prevention
Open the PDF for Opposing Effects of Androgen Deprivation and Targeted Therapy on Prostate Cancer Prevention in another window
Includes: Supplementary data
Journal Articles

Identification of Luminal Breast Cancers That Establish a Tumor-Supportive Macroenvironment Defined by Proangiogenic Platelets and Bone Marrow–Derived Cells

Hanna S. Kuznetsov, Timothy Marsh, Beth A. Markens, Zafira Castaño, April Greene-Colozzi, Samantha A. Hay, Victoria E. Brown, Andrea L. Richardson, Sabina Signoretti, Elisabeth M. Battinelli, Sandra S. McAllister
Journal: Cancer Discovery
Cancer Discov (2012) 2 (12): 1150–1165.
https://doi.org/10.1158/2159-8290.CD-12-0216
Published: 09 December 2012
View article titled, Identification of Luminal Breast Cancers That Establish a Tumor-Supportive Macroenvironment Defined by Proangiogenic Platelets and Bone Marrow–Derived Cells
Open the PDF for Identification of Luminal Breast Cancers That Establish a Tumor-Supportive Macroenvironment Defined by Proangiogenic Platelets and Bone Marrow–Derived Cells in another window
Includes: Supplementary data
Journal Articles

Genetic and Functional Studies Implicate HIF1α as a 14q Kidney Cancer Suppressor Gene

Chuan Shen, Rameen Beroukhim, Steven E. Schumacher, Jing Zhou, Michelle Chang, Sabina Signoretti, William G. Kaelin, Jr
Journal: Cancer Discovery
Cancer Discov (2011) 1 (3): 222–235.
https://doi.org/10.1158/2159-8290.CD-11-0098
Published: 15 August 2011
View article titled, Genetic and Functional Studies Implicate <em>HIF1</em>α as a 14q Kidney Cancer Suppressor Gene
Open the PDF for Genetic and Functional Studies Implicate <em>HIF1</em>α as a 14q Kidney Cancer Suppressor Gene in another window
Includes: Supplementary data