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Ralph Scully
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Journal Articles

PARP1-Driven Poly-ADP-Ribosylation Regulates BRCA1 Function in Homologous Recombination–Mediated DNA Repair

Yiduo Hu, Sarah A. Petit, Scott B. Ficarro, Kimberly J. Toomire, Anyong Xie, Elgene Lim, Shiliang A. Cao, Eunyoung Park, Michael J. Eck, Ralph Scully, Myles Brown, Jarrod A. Marto, David M. Livingston
Journal: Cancer Discovery
Cancer Discov (2014) 4 (12): 1430–1447.
https://doi.org/10.1158/2159-8290.CD-13-0891
Published: 03 December 2014
View article titled, PARP1-Driven Poly-ADP-Ribosylation Regulates BRCA1 Function in Homologous Recombination–Mediated DNA Repair
Open the PDF for PARP1-Driven Poly-ADP-Ribosylation Regulates BRCA1 Function in Homologous Recombination–Mediated DNA Repair in another window
Includes: Supplementary data
Journal Articles

Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer

Yan Liu, Kevin Marks, Glenn S. Cowley, Julian Carretero, Qingsong Liu, Thomas J.F. Nieland, Chunxiao Xu, Travis J. Cohoon, Peng Gao, Yong Zhang, Zhao Chen, Abigail B. Altabef, Jeremy H. Tchaicha, Xiaoxu Wang, Sung Choe, Edward M. Driggers, Jianming Zhang, Sean T. Bailey, Norman E. Sharpless, D. Neil Hayes, Nirali M. Patel, Pasi A. Janne, Nabeel Bardeesy, Jeffrey A. Engelman, Brendan D. Manning, Reuben J. Shaw, John M. Asara, Ralph Scully, Alec Kimmelman, Lauren A. Byers, Don L. Gibbons, Ignacio I. Wistuba, John V. Heymach, David J. Kwiatkowski, William Y. Kim, Andrew L. Kung, Nathanael S. Gray, David E. Root, Lewis C. Cantley, Kwok-Kin Wong
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2013) 3 (8): 870–879.
https://doi.org/10.1158/2159-8290.CD-13-0015
Published: 07 August 2013
View article titled, Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in <em>LKB1</em>-Mutant Lung Cancer
Open the PDF for Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in <em>LKB1</em>-Mutant Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer

Ashish Juvekar, Laura N. Burga, Hai Hu, Elaine P. Lunsford, Yasir H. Ibrahim, Judith Balmañà, Anbazhagan Rajendran, Antonella Papa, Katherine Spencer, Costas A. Lyssiotis, Caterina Nardella, Pier Paolo Pandolfi, José Baselga, Ralph Scully, John M. Asara, Lewis C. Cantley, Gerburg M. Wulf
Journal: Cancer Discovery
Cancer Discov (2012) 2 (11): 1048–1063.
https://doi.org/10.1158/2159-8290.CD-11-0336
Published: 11 November 2012
View article titled, Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer
Open the PDF for Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer in another window
Includes: Supplementary data