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Ralph J. DeBerardinis
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Journal Articles

High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non–Small Cell Lung Cancer in Patients

Ling Cai, Nia G. Hammond, Alpaslan Tasdogan, Massar Alsamraae, Chendong Yang, Robert B. Cameron, Peiran Quan, Ashley Solmonson, Wen Gu, Panayotis Pachnis, Mayher Kaur, Brianna K. Chang, Qin Zhou, Christopher T. Hensley, Quyen N. Do, Luiza Martins Nascentes Melo, Jessalyn M. Ubellacker, Akash Kaushik, Maia G. Clare, Isabel N. Alcazar, Katarzyna Kurylowicz, Joseph D. Marcuccilli, Gabriele Allies, Andrea Kutritz, Joachim Klode, Vijayashree Ramesh, Thomas J. Rogers, Aparna D. Rao, Hannah E. Crentsil, Hong Li, Fang Brister, Phyllis McDaniel, Xiaohong Xu, Bret M. Evers, Lauren G. Zacharias, Jessica Sudderth, Jian Xu, Thomas P. Mathews, Dwight Oliver, John D. Minna, John Waters, Sean J. Morrison, Kemp H. Kernstine, Brandon Faubert, Ralph J. DeBerardinis
Journal: Cancer Discovery
Cancer Discov OF1–OF15.
https://doi.org/10.1158/2159-8290.CD-23-1319
Published: 17 February 2025
View article titled, High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non–Small Cell Lung Cancer in Patients
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Includes: Supplementary data
Journal Articles

Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance

Junhua Lyu, Yuxuan Liu, Lihu Gong, Mingyi Chen, Yazan F. Madanat, Yuannyu Zhang, Feng Cai, Zhimin Gu, Hui Cao, Pranita Kaphle, Yoon Jung Kim, Fatma N. Kalkan, Helen Stephens, Kathryn E. Dickerson, Min Ni, Weina Chen, Prapti Patel, Alice S. Mims, Uma Borate, Amy Burd, Sheng F. Cai, C. Cameron Yin, M. James You, Stephen S. Chung, Robert H. Collins, Ralph J. DeBerardinis, Xin Liu, Jian Xu
Journal: Cancer Discovery
Cancer Discov (2023) 13 (1): 170–193.
https://doi.org/10.1158/2159-8290.CD-21-1661
Published: 09 January 2023
View article titled, Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance
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Includes: Supplementary data
Journal Articles

Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation

Zhimin Gu, Yuxuan Liu, Feng Cai, McKenzie Patrick, Jakub Zmajkovic, Hui Cao, Yuannyu Zhang, Alpaslan Tasdogan, Mingyi Chen, Le Qi, Xin Liu, Kailong Li, Junhua Lyu, Kathryn E. Dickerson, Weina Chen, Min Ni, Matthew E. Merritt, Sean J. Morrison, Radek C. Skoda, Ralph J. DeBerardinis, Jian Xu
Journal: Cancer Discovery
Cancer Discov (2019) 9 (9): 1228–1247.
https://doi.org/10.1158/2159-8290.CD-19-0152
Published: 03 September 2019
View article titled, Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
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Includes: Supplementary data
Journal Articles

Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

Grant M. Fischer, Ali Jalali, David A. Kircher, Won-Chul Lee, Jennifer L. McQuade, Lauren E. Haydu, Aron Y. Joon, Alexandre Reuben, Mariana P. de Macedo, Fernando C. L. Carapeto, Chendong Yang, Anuj Srivastava, Chandrashekar R. Ambati, Arun Sreekumar, Courtney W. Hudgens, Barbara Knighton, Wanleng Deng, Sherise D. Ferguson, Hussein A. Tawbi, Isabella C. Glitza, Jeffrey E. Gershenwald, Y. N. Vashisht Gopal, Patrick Hwu, Jason T. Huse, Jennifer A. Wargo, P. Andrew Futreal, Nagireddy Putluri, Alexander J. Lazar, Ralph J. DeBerardinis, Joseph R. Marszalek, Jianjun Zhang, Sheri L. Holmen, Michael T. Tetzlaff, Michael A. Davies
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (5): 628–645.
https://doi.org/10.1158/2159-8290.CD-18-1489
Published: 01 May 2019
View article titled, Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases
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Includes: Supplementary data
Journal Articles

Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma

Banu Eskiocak, Elizabeth A. McMillan, Saurabh Mendiratta, Rahul K. Kollipara, Hailei Zhang, Caroline G. Humphries, Changguang Wang, Jose Garcia-Rodriguez, Ming Ding, Aubhishek Zaman, Tracy I. Rosales, Ugur Eskiocak, Michael P. Smith, Jessica Sudderth, Kakajan Komurov, Ralph J. Deberardinis, Claudia Wellbrock, Michael A. Davies, Jennifer A. Wargo, Yonghao Yu, Jef K. De Brabander, Noelle S. Williams, Lynda Chin, Helen Rizos, Georgina V. Long, Ralf Kittler, Michael A. White
Journal: Cancer Discovery
Cancer Discov (2017) 7 (8): 832–851.
https://doi.org/10.1158/2159-8290.CD-16-0955
Published: 01 August 2017
View article titled, Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma
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Includes: Supplementary data