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Pier Paolo Pandolfi
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Journal Articles

PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage

Jinfang Zhang, Yu-Ru Lee, Fabin Dang, Wenjian Gan, Archita Venugopal Menon, Jesse M. Katon, Chih-Hung Hsu, John M. Asara, Priyanka Tibarewal, Nicholas R. Leslie, Yang Shi, Pier Paolo Pandolfi, Wenyi Wei
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (9): 1306–1323.
https://doi.org/10.1158/2159-8290.CD-18-0083
Published: 03 September 2019
View article titled, PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage
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Includes: Supplementary data
Journal Articles

Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity

Akash Patnaik, Kenneth D. Swanson, Eva Csizmadia, Aniruddh Solanki, Natalie Landon-Brace, Marina P. Gehring, Katja Helenius, Brian M. Olson, Athalia R. Pyzer, Lily C. Wang, Olivier Elemento, Jesse Novak, Thomas B. Thornley, John M. Asara, Laleh Montaser, Joshua J. Timmons, Todd M. Morgan, Yugang Wang, Elena Levantini, John G. Clohessy, Kathleen Kelly, Pier Paolo Pandolfi, Jacalyn M. Rosenblatt, David E. Avigan, Huihui Ye, Jeffrey M. Karp, Sabina Signoretti, Steven P. Balk, Lewis C. Cantley
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (7): 750–765.
https://doi.org/10.1158/2159-8290.CD-16-0778
Published: 05 July 2017
View article titled, Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity
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Includes: Supplementary data
Journal Articles

The Epitranscriptome of Noncoding RNAs in Cancer

Manel Esteller, Pier Paolo Pandolfi
Journal: Cancer Discovery
Cancer Discov (2017) 7 (4): 359–368.
https://doi.org/10.1158/2159-8290.CD-16-1292
Published: 02 April 2017
View article titled, The Epitranscriptome of Noncoding RNAs in Cancer
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Journal Articles

The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function

Lixin Wan, Ming Chen, Juxiang Cao, Xiangpeng Dai, Qing Yin, Jinfang Zhang, Su-Jung Song, Ying Lu, Jing Liu, Hiroyuki Inuzuka, Jesse M. Katon, Kelsey Berry, Jacqueline Fung, Christopher Ng, Pengda Liu, Min Sup Song, Lian Xue, Roderick T. Bronson, Marc W. Kirschner, Rutao Cui, Pier Paolo Pandolfi, Wenyi Wei
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (4): 424–441.
https://doi.org/10.1158/2159-8290.CD-16-0647
Published: 02 April 2017
View article titled, The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function
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Includes: Supplementary data
Journal Articles

In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K–AKT Signaling at Endosomes

Chen Li Chew, Andrea Lunardi, Federico Gulluni, Daniel T. Ruan, Ming Chen, Leonardo Salmena, Michiya Nishino, Antonella Papa, Christopher Ng, Jacqueline Fung, John G. Clohessy, Junko Sasaki, Takehiko Sasaki, Roderick T. Bronson, Emilio Hirsch, Pier Paolo Pandolfi
Journal: Cancer Discovery
Cancer Discov (2015) 5 (7): 740–751.
https://doi.org/10.1158/2159-8290.CD-14-1347
Published: 06 July 2015
View article titled, <em>In Vivo</em> Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K–AKT Signaling at Endosomes
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Includes: Supplementary data
Journal Articles

Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis

Andrea Lunardi, Shohreh Varmeh, Ming Chen, Riccardo Taulli, Jlenia Guarnerio, Ugo Ala, Nina Seitzer, Tomoki Ishikawa, Brett S. Carver, Robin M. Hobbs, Valentina Quarantotti, Christopher Ng, Alice H. Berger, Caterina Nardella, Laura Poliseno, Rodolfo Montironi, Mireia Castillo-Martin, Carlos Cordon-Cardo, Sabina Signoretti, Pier Paolo Pandolfi
Journal: Cancer Discovery
Cancer Discov (2015) 5 (5): 550–563.
https://doi.org/10.1158/2159-8290.CD-13-1050
Published: 03 May 2015
View article titled, Suppression of <em>CHK1</em> by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis
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Includes: Supplementary data
Journal Articles

A Genetic Platform to Model Sarcomagenesis from Primary Adult Mesenchymal Stem Cells

Jlenia Guarnerio, Luisa Riccardi, Riccardo Taulli, Takahiro Maeda, Guocan Wang, Robin M. Hobbs, Min Sup Song, Paolo Sportoletti, Rosa Bernardi, Roderick T. Bronson, Mireia Castillo-Martin, Carlos Cordon-Cardo, Andrea Lunardi, Pier Paolo Pandolfi
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2015) 5 (4): 396–409.
https://doi.org/10.1158/2159-8290.CD-14-1022
Published: 05 April 2015
View article titled, A Genetic Platform to Model Sarcomagenesis from Primary Adult Mesenchymal Stem Cells
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Includes: Supplementary data
Journal Articles

Vulnerabilities of PTEN–TP53-Deficient Prostate Cancers to Compound PARP–PI3K Inhibition

Enrique González-Billalabeitia, Nina Seitzer, Su Jung Song, Min Sup Song, Akash Patnaik, Xue-Song Liu, Mirjam T. Epping, Antonella Papa, Robin M. Hobbs, Ming Chen, Andrea Lunardi, Christopher Ng, Kaitlyn A. Webster, Sabina Signoretti, Massimo Loda, John M. Asara, Caterina Nardella, John G. Clohessy, Lewis C. Cantley, Pier Paolo Pandolfi
Journal: Cancer Discovery
Cancer Discov (2014) 4 (8): 896–904.
https://doi.org/10.1158/2159-8290.CD-13-0230
Published: 03 August 2014
View article titled, Vulnerabilities of <em>PTEN</em>–<em>TP53</em>-Deficient Prostate Cancers to Compound PARP–PI3K Inhibition
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Includes: Supplementary data
Journal Articles

ceRNA Cross-Talk in Cancer: When ce-bling Rivalries Go Awry

Florian A. Karreth, Pier Paolo Pandolfi
Journal: Cancer Discovery
Cancer Discov (2013) 3 (10): 1113–1121.
https://doi.org/10.1158/2159-8290.CD-13-0202
Published: 10 October 2013
View article titled, ceRNA Cross-Talk in Cancer: When ce-bling Rivalries Go Awry
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Journal Articles

Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer

Ashish Juvekar, Laura N. Burga, Hai Hu, Elaine P. Lunsford, Yasir H. Ibrahim, Judith Balmañà, Anbazhagan Rajendran, Antonella Papa, Katherine Spencer, Costas A. Lyssiotis, Caterina Nardella, Pier Paolo Pandolfi, José Baselga, Ralph Scully, John M. Asara, Lewis C. Cantley, Gerburg M. Wulf
Journal: Cancer Discovery
Cancer Discov (2012) 2 (11): 1048–1063.
https://doi.org/10.1158/2159-8290.CD-11-0336
Published: 11 November 2012
View article titled, Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer
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Includes: Supplementary data
Journal Articles

The APL Paradigm and the “Co-Clinical Trial” Project

Caterina Nardella, Andrea Lunardi, Akash Patnaik, Lewis C. Cantley, Pier Paolo Pandolfi
Journal: Cancer Discovery
Cancer Discov (2011) 1 (2): 108–116.
https://doi.org/10.1158/2159-8290.CD-11-0061
Published: 17 July 2011
View article titled, The APL Paradigm and the “Co-Clinical Trial” Project
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