1-9 of 9
Philip J. Stephens
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma

Ferdinandos Skoulidis, Michael E. Goldberg, Danielle M. Greenawalt, Matthew D. Hellmann, Mark M. Awad, Justin F. Gainor, Alexa B. Schrock, Ryan J. Hartmaier, Sally E. Trabucco, Laurie Gay, Siraj M. Ali, Julia A. Elvin, Gaurav Singal, Jeffrey S. Ross, David Fabrizio, Peter M. Szabo, Han Chang, Ariella Sasson, Sujaya Srinivasan, Stefan Kirov, Joseph Szustakowski, Patrik Vitazka, Robin Edwards, Jose A. Bufill, Neelesh Sharma, Sai-Hong I. Ou, Nir Peled, David R. Spigel, Hira Rizvi, Elizabeth Jimenez Aguilar, Brett W. Carter, Jeremy Erasmus, Darragh F. Halpenny, Andrew J. Plodkowski, Niamh M. Long, Mizuki Nishino, Warren L. Denning, Ana Galan-Cobo, Haifa Hamdi, Taghreed Hirz, Pan Tong, Jing Wang, Jaime Rodriguez-Canales, Pamela A. Villalobos, Edwin R. Parra, Neda Kalhor, Lynette M. Sholl, Jennifer L. Sauter, Achim A. Jungbluth, Mari Mino-Kenudson, Roxana Azimi, Yasir Y. Elamin, Jianjun Zhang, Giulia C. Leonardi, Fei Jiang, Kwok-Kin Wong, J. Jack Lee, Vassiliki A. Papadimitrakopoulou, Ignacio I. Wistuba, Vincent A. Miller, Garrett M. Frampton, Jedd D. Wolchok, Alice T. Shaw, Pasi A. Jänne, Philip J. Stephens, Charles M. Rudin, William J. Geese, Lee A. Albacker, John V. Heymach
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (7): 822–835.
https://doi.org/10.1158/2159-8290.CD-18-0099
Published: 01 July 2018
View article titled, <em>STK11/LKB1</em> Mutations and PD-1 Inhibitor Resistance in <em>KRAS</em>-Mutant Lung Adenocarcinoma
Open the PDF for <em>STK11/LKB1</em> Mutations and PD-1 Inhibitor Resistance in <em>KRAS</em>-Mutant Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

EGFR Fusions as Novel Therapeutic Targets in Lung Cancer

Kartik Konduri, Jean-Nicolas Gallant, Young Kwang Chae, Francis J. Giles, Barbara J. Gitlitz, Kyle Gowen, Eiki Ichihara, Taofeek K. Owonikoko, Vijay Peddareddigari, Suresh S. Ramalingam, Satyanarayan K. Reddy, Beth Eaby-Sandy, Tiziana Vavalà, Andrew Whiteley, Heidi Chen, Yingjun Yan, Jonathan H. Sheehan, Jens Meiler, Deborah Morosini, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller, Siraj M. Ali, Christine M. Lovly
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2016) 6 (6): 601–611.
https://doi.org/10.1158/2159-8290.CD-16-0075
Published: 02 June 2016
View article titled, <em>EGFR</em> Fusions as Novel Therapeutic Targets in Lung Cancer
Open the PDF for <em>EGFR</em> Fusions as Novel Therapeutic Targets in Lung Cancer in another window
Includes: Supplementary data
Journal Articles

BRAFV600E Mutations in High-Grade Colorectal Neuroendocrine Tumors May Predict Responsiveness to BRAF–MEK Combination Therapy

Samuel J. Klempner, Bruce Gershenhorn, Phu Tran, Thomas K. Lee, Mark G. Erlander, Kyle Gowen, Alexa B. Schrock, Deborah Morosini, Jeffrey S. Ross, Vincent A. Miller, Philip J. Stephens, Sai-Hong Ignatius Ou, Siraj M. Ali
Journal: Cancer Discovery
Cancer Discov (2016) 6 (6): 594–600.
https://doi.org/10.1158/2159-8290.CD-15-1192
Published: 02 June 2016
View article titled, <em>BRAF</em><sup>V600E</sup> Mutations in High-Grade Colorectal Neuroendocrine Tumors May Predict Responsiveness to BRAF–MEK Combination Therapy
Open the PDF for <em>BRAF</em><sup>V600E</sup> Mutations in High-Grade Colorectal Neuroendocrine Tumors May Predict Responsiveness to BRAF–MEK Combination Therapy in another window
Journal Articles

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Eli L. Diamond, Benjamin H. Durham, Julien Haroche, Zhan Yao, Jing Ma, Sameer A. Parikh, Zhaoming Wang, John Choi, Eunhee Kim, Fleur Cohen-Aubart, Stanley Chun-Wei Lee, Yijun Gao, Jean-Baptiste Micol, Patrick Campbell, Michael P. Walsh, Brooke Sylvester, Igor Dolgalev, Olga Aminova, Adriana Heguy, Paul Zappile, Joy Nakitandwe, Chezi Ganzel, James D. Dalton, David W. Ellison, Juvianee Estrada-Veras, Mario Lacouture, William A. Gahl, Philip J. Stephens, Vincent A. Miller, Jeffrey S. Ross, Siraj M. Ali, Samuel R. Briggs, Omotayo Fasan, Jared Block, Sebastien Héritier, Jean Donadieu, David B. Solit, David M. Hyman, José Baselga, Filip Janku, Barry S. Taylor, Christopher Y. Park, Zahir Amoura, Ahmet Dogan, Jean-Francois Emile, Neal Rosen, Tanja A. Gruber, Omar Abdel-Wahab
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2016) 6 (2): 154–165.
https://doi.org/10.1158/2159-8290.CD-15-0913
Published: 04 February 2016
View article titled, Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms
Open the PDF for Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms in another window
Includes: Supplementary data
Journal Articles

RICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors

Haiying Cheng, Yiyu Zou, Jeffrey S. Ross, Kai Wang, Xuewen Liu, Balazs Halmos, Siraj M. Ali, Huijie Liu, Amit Verma, Cristina Montagna, Abraham Chachoua, Sanjay Goel, Edward L. Schwartz, Changcheng Zhu, Jidong Shan, Yiting Yu, Kira Gritsman, Roman Yelensky, Doron Lipson, Geoff Otto, Matthew Hawryluk, Philip J. Stephens, Vincent A. Miller, Bilal Piperdi, Roman Perez-Soler
Journal: Cancer Discovery
Cancer Discov (2015) 5 (12): 1262–1270.
https://doi.org/10.1158/2159-8290.CD-14-0971
Published: 03 December 2015
View article titled, <em>RICTOR</em> Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors
Open the PDF for <em>RICTOR</em> Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors in another window
Includes: Supplementary data
Journal Articles

An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101

Robert C. Doebele, Lara E. Davis, Aria Vaishnavi, Anh T. Le, Adriana Estrada-Bernal, Stephen Keysar, Antonio Jimeno, Marileila Varella-Garcia, Dara L. Aisner, Yali Li, Philip J. Stephens, Deborah Morosini, Brian B. Tuch, Michele Fernandes, Nisha Nanda, Jennifer A. Low
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2015) 5 (10): 1049–1057.
https://doi.org/10.1158/2159-8290.CD-15-0443
Published: 30 September 2015
View article titled, An Oncogenic <em>NTRK</em> Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101
Open the PDF for An Oncogenic <em>NTRK</em> Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101 in another window
Includes: Supplementary data
Journal Articles

Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors

Garrett M. Frampton, Siraj M. Ali, Mark Rosenzweig, Juliann Chmielecki, Xinyuan Lu, Todd M. Bauer, Mikhail Akimov, Jose A. Bufill, Carrie Lee, David Jentz, Rick Hoover, Sai-Hong Ignatius Ou, Ravi Salgia, Tim Brennan, Zachary R. Chalmers, Savina Jaeger, Alan Huang, Julia A. Elvin, Rachel Erlich, Alex Fichtenholtz, Kyle A. Gowen, Joel Greenbowe, Adrienne Johnson, Depinder Khaira, Caitlin McMahon, Eric M. Sanford, Steven Roels, Jared White, Joel Greshock, Robert Schlegel, Doron Lipson, Roman Yelensky, Deborah Morosini, Jeffrey S. Ross, Eric Collisson, Malte Peters, Philip J. Stephens, Vincent A. Miller
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2015) 5 (8): 850–859.
https://doi.org/10.1158/2159-8290.CD-15-0285
Published: 03 August 2015
View article titled, Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors
Open the PDF for Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors in another window
Includes: Supplementary data
Journal Articles

Comprehensive Genomic Profiling of Pancreatic Acinar Cell Carcinomas Identifies Recurrent RAF Fusions and Frequent Inactivation of DNA Repair Genes

Juliann Chmielecki, Katherine E. Hutchinson, Garrett M. Frampton, Zachary R. Chalmers, Adrienne Johnson, Chanjuan Shi, Julia Elvin, Siraj M. Ali, Jeffrey S. Ross, Olca Basturk, Sohail Balasubramanian, Doron Lipson, Roman Yelensky, William Pao, Vincent A. Miller, David S. Klimstra, Philip J. Stephens
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2014) 4 (12): 1398–1405.
https://doi.org/10.1158/2159-8290.CD-14-0617
Published: 03 December 2014
View article titled, Comprehensive Genomic Profiling of Pancreatic Acinar Cell Carcinomas Identifies Recurrent <em>RAF</em> Fusions and Frequent Inactivation of DNA Repair Genes
Open the PDF for Comprehensive Genomic Profiling of Pancreatic Acinar Cell Carcinomas Identifies Recurrent <em>RAF</em> Fusions and Frequent Inactivation of DNA Repair Genes in another window
Includes: Supplementary data
Journal Articles

Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions

Christine M. Lovly, Abha Gupta, Doron Lipson, Geoff Otto, Tina Brennan, Catherine T. Chung, Scott C. Borinstein, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller, Cheryl M. Coffin
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2014) 4 (8): 889–895.
https://doi.org/10.1158/2159-8290.CD-14-0377
Published: 03 August 2014
View article titled, Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions
Open the PDF for Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions in another window
Includes: Supplementary data