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Peter S. Hammerman
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Journal Articles

Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis

Katsuhiro Togami, Sun Sook Chung, Vikas Madan, Christopher A.G. Booth, Christopher M. Kenyon, Lucia Cabal-Hierro, Justin Taylor, Sunhee S. Kim, Gabriel K. Griffin, Mahmoud Ghandi, Jia Li, Yvonne Y. Li, Fanny Angelot-Delettre, Sabeha Biichle, Michael Seiler, Silvia Buonamici, Scott B. Lovitch, Abner Louissaint, Jr, Elizabeth A. Morgan, Fabrice Jardin, Pier Paolo Piccaluga, David M. Weinstock, Peter S. Hammerman, Henry Yang, Marina Konopleva, Naveen Pemmaraju, Francine Garnache-Ottou, Omar Abdel-Wahab, H. Phillip Koeffler, Andrew A. Lane
Journal: Cancer Discovery
Cancer Discov (2022) 12 (2): 522–541.
https://doi.org/10.1158/2159-8290.CD-20-1513
Published: 01 February 2022
View article titled, Sex-Biased <em>ZRSR2</em> Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis
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Includes: Supplementary data
Journal Articles

In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma

Fei Li, Qingyuan Huang, Troy A. Luster, Hai Hu, Hua Zhang, Wai-Lung Ng, Alireza Khodadadi-Jamayran, Wei Wang, Ting Chen, Jiehui Deng, Michela Ranieri, Zhaoyuan Fang, Val Pyon, Catríona M. Dowling, Ece Bagdatlioglu, Christina Almonte, Kristen Labbe, Heather Silver, Alexandra R. Rabin, Kandarp Jani, Aristotelis Tsirigos, Thales Papagiannakopoulos, Peter S. Hammerman, Vamsidhar Velcheti, Gordon J. Freeman, Jun Qi, George Miller, Kwok-Kin Wong
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (2): 270–287.
https://doi.org/10.1158/2159-8290.CD-19-0780
Published: 05 February 2020
View article titled, <em>In Vivo</em> Epigenetic CRISPR Screen Identifies <em>Asf1a</em> as an Immunotherapeutic Target in <em>Kras</em>-Mutant Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression

Maria Rusan, Kapsok Li, Yvonne Li, Camilla L. Christensen, Brian J. Abraham, Nicholas Kwiatkowski, Kevin A. Buczkowski, Bruno Bockorny, Ting Chen, Shuai Li, Kevin Rhee, Haikuo Zhang, Wankun Chen, Hideki Terai, Tiffany Tavares, Alan L. Leggett, Tianxia Li, Yichen Wang, Tinghu Zhang, Tae-Jung Kim, Sook-Hee Hong, Neermala Poudel-Neupane, Michael Silkes, Tenny Mudianto, Li Tan, Takeshi Shimamura, Matthew Meyerson, Adam J. Bass, Hideo Watanabe, Nathanael S. Gray, Richard A. Young, Kwok-Kin Wong, Peter S. Hammerman
Journal: Cancer Discovery
Cancer Discov (2018) 8 (1): 59–73.
https://doi.org/10.1158/2159-8290.CD-17-0461
Published: 07 January 2018
View article titled, Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression
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Includes: Supplementary data
Journal Articles

Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non–Small Cell Lung Cancer

Dennis O. Adeegbe, Yan Liu, Patrick H. Lizotte, Yusuke Kamihara, Amir R. Aref, Christina Almonte, Ruben Dries, Yuyang Li, Shengwu Liu, Xiaoen Wang, Tiquella Warner-Hatten, Jessica Castrillon, Guo-Cheng Yuan, Neermala Poudel-Neupane, Haikuo Zhang, Jennifer L. Guerriero, Shiwei Han, Mark M. Awad, David A. Barbie, Jerome Ritz, Simon S. Jones, Peter S. Hammerman, James Bradner, Steven N. Quayle, Kwok-Kin Wong
Journal: Cancer Discovery
Cancer Discov (2017) 7 (8): 852–867.
https://doi.org/10.1158/2159-8290.CD-16-1020
Published: 01 August 2017
View article titled, Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer

Haikuo Zhang, Jun Qi, Jaime M. Reyes, Lewyn Li, Prakash K. Rao, Fugen Li, Charles Y. Lin, Jennifer A. Perry, Matthew A. Lawlor, Alexander Federation, Thomas De Raedt, Yvonne Y. Li, Yan Liu, Melissa A. Duarte, Yanxi Zhang, Grit S. Herter-Sprie, Eiki Kikuchi, Julian Carretero, Charles M. Perou, Jacob B. Reibel, Joshiawa Paulk, Roderick T. Bronson, Hideo Watanabe, Christine Fillmore Brainson, Carla F. Kim, Peter S. Hammerman, Myles Brown, Karen Cichowski, Henry Long, James E. Bradner, Kwok-Kin Wong
Journal: Cancer Discovery
Cancer Discov (2016) 6 (9): 1006–1021.
https://doi.org/10.1158/2159-8290.CD-16-0164
Published: 31 August 2016
View article titled, Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer
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Includes: Supplementary data
Journal Articles

Therapeutic Insights from Genomic Studies of Head and Neck Squamous Cell Carcinomas

Peter S. Hammerman, D. Neil Hayes, Jennifer R. Grandis
Journal: Cancer Discovery
Cancer Discov (2015) 5 (3): 239–244.
https://doi.org/10.1158/2159-8290.CD-14-1205
Published: 05 March 2015
View article titled, Therapeutic Insights from Genomic Studies of Head and Neck Squamous Cell Carcinomas
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Journal Articles

Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors

Esra A. Akbay, Shohei Koyama, Julian Carretero, Abigail Altabef, Jeremy H. Tchaicha, Camilla L. Christensen, Oliver R. Mikse, Andrew D. Cherniack, Ellen M. Beauchamp, Trevor J. Pugh, Matthew D. Wilkerson, Peter E. Fecci, Mohit Butaney, Jacob B. Reibel, Margaret Soucheray, Travis J. Cohoon, Pasi A. Janne, Matthew Meyerson, D. Neil Hayes, Geoffrey I. Shapiro, Takeshi Shimamura, Lynette M. Sholl, Scott J. Rodig, Gordon J. Freeman, Peter S. Hammerman, Glenn Dranoff, Kwok-Kin Wong
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2013) 3 (12): 1355–1363.
https://doi.org/10.1158/2159-8290.CD-13-0310
Published: 10 December 2013
View article titled, Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors
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Includes: Supplementary data
Journal Articles

Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive Biomarkers

Vivian W.Y. Lui, Matthew L. Hedberg, Hua Li, Bhavana S. Vangara, Kelsey Pendleton, Yan Zeng, Yiling Lu, Qiuhong Zhang, Yu Du, Breean R. Gilbert, Maria Freilino, Sam Sauerwein, Noah D. Peyser, Dong Xiao, Brenda Diergaarde, Lin Wang, Simion Chiosea, Raja Seethala, Jonas T. Johnson, Seungwon Kim, Umamaheswar Duvvuri, Robert L. Ferris, Marjorie Romkes, Tomoko Nukui, Patrick Kwok-Shing Ng, Levi A. Garraway, Peter S. Hammerman, Gordon B. Mills, Jennifer R. Grandis
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2013) 3 (7): 761–769.
https://doi.org/10.1158/2159-8290.CD-13-0103
Published: 10 July 2013
View article titled, Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive Biomarkers
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Includes: Supplementary data
Journal Articles

Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

Peter S. Hammerman, Martin L. Sos, Alex H. Ramos, Chunxiao Xu, Amit Dutt, Wenjun Zhou, Lear E. Brace, Brittany A. Woods, Wenchu Lin, Jianming Zhang, Xianming Deng, Sang Min Lim, Stefanie Heynck, Martin Peifer, Jeffrey R. Simard, Michael S. Lawrence, Robert C. Onofrio, Helga B. Salvesen, Danila Seidel, Thomas Zander, Johannes M. Heuckmann, Alex Soltermann, Holger Moch, Mirjam Koker, Frauke Leenders, Franziska Gabler, Silvia Querings, Sascha Ansén, Elisabeth Brambilla, Christian Brambilla, Philippe Lorimier, Odd Terje Brustugun, Åslaug Helland, Iver Petersen, Joachim H. Clement, Harry Groen, Wim Timens, Hannie Sietsma, Erich Stoelben, Jürgen Wolf, David G. Beer, Ming Sound Tsao, Megan Hanna, Charles Hatton, Michael J. Eck, Pasi A. Janne, Bruce E. Johnson, Wendy Winckler, Heidi Greulich, Adam J. Bass, Jeonghee Cho, Daniel Rauh, Nathanael S. Gray, Kwok-Kin Wong, Eric B. Haura, Roman K. Thomas, Matthew Meyerson
Journal: Cancer Discovery
Cancer Discov (2011) 1 (1): 78–89.
https://doi.org/10.1158/2159-8274.CD-11-0005
Published: 01 June 2011
View article titled, Mutations in the <em>DDR2</em> Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer
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Includes: Multimedia, Supplementary data