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Nina Weichert-Leahey
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Journal Articles

Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma

Presha Rajbhandari, Gonzalo Lopez, Claudia Capdevila, Beatrice Salvatori, Jiyang Yu, Ruth Rodriguez-Barrueco, Daniel Martinez, Mark Yarmarkovich, Nina Weichert-Leahey, Brian J. Abraham, Mariano J. Alvarez, Archana Iyer, Jo Lynne Harenza, Derek Oldridge, Katleen De Preter, Jan Koster, Shahab Asgharzadeh, Robert C. Seeger, Jun S. Wei, Javed Khan, Jo Vandesompele, Pieter Mestdagh, Rogier Versteeg, A. Thomas Look, Richard A. Young, Antonio Iavarone, Anna Lasorella, Jose M. Silva, John M. Maris, Andrea Califano
Journal: Cancer Discovery
Cancer Discov (2018) 8 (5): 582–599.
https://doi.org/10.1158/2159-8290.CD-16-0861
Published: 30 April 2018
View article titled, Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma
Open the PDF for Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification

Mark W. Zimmerman, Yu Liu, Shuning He, Adam D. Durbin, Brian J. Abraham, John Easton, Ying Shao, Beisi Xu, Shizhen Zhu, Xiaoling Zhang, Zhaodong Li, Nina Weichert-Leahey, Richard A. Young, Jinghui Zhang, A. Thomas Look
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (3): 320–335.
https://doi.org/10.1158/2159-8290.CD-17-0993
Published: 01 March 2018
View article titled, <em>MYC</em> Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification
Open the PDF for <em>MYC</em> Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification in another window
Includes: Supplementary data