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Nancy U. Lin
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Journal Articles

The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer

Seth A. Wander, Ofir Cohen, Xueqian Gong, Gabriela N. Johnson, Jorge E. Buendia-Buendia, Maxwell R. Lloyd, Dewey Kim, Flora Luo, Pingping Mao, Karla Helvie, Kailey J. Kowalski, Utthara Nayar, Adrienne G. Waks, Stephen H. Parsons, Ricardo Martinez, Lacey M. Litchfield, Xiang S. Ye, Chunping Yu, Valerie M. Jansen, John R. Stille, Patricia S. Smith, Gerard J. Oakley, Quincy S. Chu, Gerald Batist, Melissa E. Hughes, Jill D. Kremer, Levi A. Garraway, Eric P. Winer, Sara M. Tolaney, Nancy U. Lin, Sean G. Buchanan, Nikhil Wagle
Journal: Cancer Discovery
Cancer Discov (2020) 10 (8): 1174–1193.
https://doi.org/10.1158/2159-8290.CD-19-1390
Published: 03 August 2020
View articletitled, The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer
Open the PDF for The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer in another window
Includes: Supplementary data
Journal Articles

HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers

Bob T. Li, Flavia Michelini, Sandra Misale, Emiliano Cocco, Laura Baldino, Yanyan Cai, Sophie Shifman, Hai-Yan Tu, Mackenzie L. Myers, Chongrui Xu, Marissa Mattar, Inna Khodos, Megan Little, Besnik Qeriqi, Gregory Weitsman, Clare J. Wilhem, Alshad S. Lalani, Irmina Diala, Rachel A. Freedman, Nancy U. Lin, David B. Solit, Michael F. Berger, Paul R. Barber, Tony Ng, Michael Offin, James M. Isbell, David R. Jones, Helena A. Yu, Sheeno Thyparambil, Wei-Li Liao, Anuja Bhalkikar, Fabiola Cecchi, David M. Hyman, Jason S. Lewis, Darren J. Buonocore, Alan L. Ho, Vicky Makker, Jorge S. Reis-Filho, Pedram Razavi, Maria E. Arcila, Mark G. Kris, John T. Poirier, Ronglai Shen, Junji Tsurutani, Gary A. Ulaner, Elisa de Stanchina, Neal Rosen, Charles M. Rudin, Maurizio Scaltriti
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (5): 674–687.
https://doi.org/10.1158/2159-8290.CD-20-0215
Published: 01 May 2020
View articletitled, HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers
Open the PDF for HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers in another window
Includes: Supplementary data
Journal Articles

Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment

Ana C. Garrido-Castro, Nancy U. Lin, Kornelia Polyak
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (2): 176–198.
https://doi.org/10.1158/2159-8290.CD-18-1177
Published: 08 February 2019
View articletitled, Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment
Open the PDF for Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment in another window
Journal Articles

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

Priscilla K. Brastianos, Scott L. Carter, Sandro Santagata, Daniel P. Cahill, Amaro Taylor-Weiner, Robert T. Jones, Eliezer M. Van Allen, Michael S. Lawrence, Peleg M. Horowitz, Kristian Cibulskis, Keith L. Ligon, Josep Tabernero, Joan Seoane, Elena Martinez-Saez, William T. Curry, Ian F. Dunn, Sun Ha Paek, Sung-Hye Park, Aaron McKenna, Aaron Chevalier, Mara Rosenberg, Frederick G. Barker, II, Corey M. Gill, Paul Van Hummelen, Aaron R. Thorner, Bruce E. Johnson, Mai P. Hoang, Toni K. Choueiri, Sabina Signoretti, Carrie Sougnez, Michael S. Rabin, Nancy U. Lin, Eric P. Winer, Anat Stemmer-Rachamimov, Matthew Meyerson, Levi Garraway, Stacey Gabriel, Eric S. Lander, Rameen Beroukhim, Tracy T. Batchelor, José Baselga, David N. Louis, Gad Getz, William C. Hahn
Journal: Cancer Discovery
Cancer Discov (2015) 5 (11): 1164–1177.
https://doi.org/10.1158/2159-8290.CD-15-0369
Published: 01 November 2015
View articletitled, Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
Open the PDF for Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets in another window
Includes: Supplementary data