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Monica L. Guzman
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Journal Articles

Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML

Cihangir Duy, Matt Teater, Francine E. Garrett-Bakelman, Tak C. Lee, Cem Meydan, Jacob L. Glass, Meng Li, Johannes C. Hellmuth, Helai P. Mohammad, Kimberly N. Smitheman, Alan H. Shih, Omar Abdel-Wahab, Martin S. Tallman, Monica L. Guzman, David Muench, H. Leighton Grimes, Gail J. Roboz, Ryan G. Kruger, Caretha L. Creasy, Elisabeth M. Paietta, Ross L. Levine, Martin Carroll, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2019) 9 (7): 872–889.
https://doi.org/10.1158/2159-8290.CD-19-0106
Published: 01 July 2019
View article titled, Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML
Open the PDF for Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML in another window
Includes: Supplementary data
Journal Articles

Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Jacob L. Glass, Duane Hassane, Bas J. Wouters, Hiroyoshi Kunimoto, Roberto Avellino, Francine E. Garrett-Bakelman, Olga A. Guryanova, Robert Bowman, Shira Redlich, Andrew M. Intlekofer, Cem Meydan, Tingting Qin, Mame Fall, Alicia Alonso, Monica L. Guzman, Peter J.M. Valk, Craig B. Thompson, Ross Levine, Olivier Elemento, Ruud Delwel, Ari Melnick, Maria E. Figueroa
Journal: Cancer Discovery
Cancer Discov (2017) 7 (8): 868–883.
https://doi.org/10.1158/2159-8290.CD-16-1032
Published: 01 August 2017
View article titled, Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers
Open the PDF for Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers in another window
Includes: Supplementary data
Journal Articles

Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia

Huimin Geng, Sarah Brennan, Thomas A. Milne, Wei-Yi Chen, Yushan Li, Christian Hurtz, Soo-Mi Kweon, Lynette Zickl, Seyedmehdi Shojaee, Donna Neuberg, Chuanxin Huang, Debabrata Biswas, Yuan Xin, Janis Racevskis, Rhett P. Ketterling, Selina M. Luger, Hillard Lazarus, Martin S. Tallman, Jacob M. Rowe, Mark R. Litzow, Monica L. Guzman, C. David Allis, Robert G. Roeder, Markus Müschen, Elisabeth Paietta, Olivier Elemento, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2012) 2 (11): 1004–1023.
https://doi.org/10.1158/2159-8290.CD-12-0208
Published: 11 November 2012
View article titled, Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia
Open the PDF for Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data