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Mithat Gönen
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Journal Articles

A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti–PD-1 Agent Pembrolizumab

Prasad S. Adusumilli, Marjorie G. Zauderer, Isabelle Rivière, Stephen B. Solomon, Valerie W. Rusch, Roisin E. O'Cearbhaill, Amy Zhu, Waseem Cheema, Navin K. Chintala, Elizabeth Halton, John Pineda, Rocio Perez-Johnston, Kay See Tan, Bobby Daly, Jose A. Araujo Filho, Daniel Ngai, Erin McGee, Alain Vincent, Claudia Diamonte, Jennifer L. Sauter, Shanu Modi, Devanjan Sikder, Brigitte Senechal, Xiuyan Wang, William D. Travis, Mithat Gönen, Charles M. Rudin, Renier J. Brentjens, David R. Jones, Michel Sadelain
Journal: Cancer Discovery
Cancer Discov (2021) 11 (11): 2748–2763.
https://doi.org/10.1158/2159-8290.CD-21-0407
Published: 01 November 2021
View article titled, A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti–PD-1 Agent Pembrolizumab
Open the PDF for A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti–PD-1 Agent Pembrolizumab in another window
Includes: Supplementary data
Journal Articles

The Evolutionary Origins of Recurrent Pancreatic Cancer

Hitomi Sakamoto, Marc A. Attiyeh, Jeffrey M. Gerold, Alvin P. Makohon-Moore, Akimasa Hayashi, Jungeui Hong, Rajya Kappagantula, Lance Zhang, Jerry P. Melchor, Johannes G. Reiter, Alexander Heyde, Craig M. Bielski, Alexander V. Penson, Mithat Gönen, Debyani Chakravarty, Eileen M. O'Reilly, Laura D. Wood, Ralph H. Hruban, Martin A. Nowak, Nicholas D. Socci, Barry S. Taylor, Christine A. Iacobuzio-Donahue
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (6): 792–805.
https://doi.org/10.1158/2159-8290.CD-19-1508
Published: 01 June 2020
View article titled, The Evolutionary Origins of Recurrent Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia

Bianca D. Santomasso, Jae H. Park, Darin Salloum, Isabelle Riviere, Jessica Flynn, Elena Mead, Elizabeth Halton, Xiuyan Wang, Brigitte Senechal, Terence Purdon, Justin R. Cross, Hui Liu, Behroze Vachha, Xi Chen, Lisa M. DeAngelis, Daniel Li, Yvette Bernal, Mithat Gonen, Hans-Guido Wendel, Michel Sadelain, Renier J. Brentjens
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (8): 958–971.
https://doi.org/10.1158/2159-8290.CD-17-1319
Published: 02 August 2018
View article titled, Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia
Open the PDF for Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data
Journal Articles

MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia

Fiona C. Brown, Eric Still, Richard P. Koche, Christina Y. Yim, Sumiko Takao, Paolo Cifani, Casie Reed, Shehana Gunasekera, Scott B. Ficarro, Peter Romanienko, Willie Mark, Craig McCarthy, Elisa de Stanchina, Mithat Gonen, Venkatraman Seshan, Patrick Bhola, Conor O'Donnell, Barbara Spitzer, Crystal Stutzke, Vincent-Philippe Lavallée, Josée Hébert, Andrei V. Krivtsov, Ari Melnick, Elisabeth M. Paietta, Martin S. Tallman, Anthony Letai, Guy Sauvageau, Gayle Pouliot, Ross Levine, Jarrod A Marto, Scott A. Armstrong, Alex Kentsis
Journal: Cancer Discovery
Cancer Discov (2018) 8 (4): 478–497.
https://doi.org/10.1158/2159-8290.CD-17-1271
Published: 01 April 2018
View article titled, MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia
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Includes: Supplementary data
Journal Articles

Evolutionary Pathways in BRCA1-Associated Breast Tumors

Filipe C. Martins, Subhajyoti De, Vanessa Almendro, Mithat Gönen, So Yeon Park, Joanne L. Blum, William Herlihy, Gabrielle Ethington, Stuart J. Schnitt, Nadine Tung, Judy E. Garber, Katharina Fetten, Franziska Michor, Kornelia Polyak
Journal: Cancer Discovery
Cancer Discov (2012) 2 (6): 503–511.
https://doi.org/10.1158/2159-8290.CD-11-0325
Published: 07 June 2012
View article titled, Evolutionary Pathways in BRCA1-Associated Breast Tumors
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Includes: Multimedia, Supplementary data