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Mireia Castillo-Martin
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Journal Articles

MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2

Dawid G. Nowak, Hyejin Cho, Tali Herzka, Kaitlin Watrud, Daniel V. DeMarco, Victoria M.Y. Wang, Serif Senturk, Christof Fellmann, David Ding, Tumas Beinortas, David Kleinman, Muhan Chen, Raffaella Sordella, John E. Wilkinson, Mireia Castillo-Martin, Carlos Cordon-Cardo, Brian D. Robinson, Lloyd C. Trotman
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2015) 5 (6): 636–651.
https://doi.org/10.1158/2159-8290.CD-14-1113
Published: 01 June 2015
View article titled, MYC Drives <em>Pten/Trp53</em>-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2
Open the PDF for MYC Drives <em>Pten/Trp53</em>-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2 in another window
Includes: Supplementary data
Journal Articles

Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis

Andrea Lunardi, Shohreh Varmeh, Ming Chen, Riccardo Taulli, Jlenia Guarnerio, Ugo Ala, Nina Seitzer, Tomoki Ishikawa, Brett S. Carver, Robin M. Hobbs, Valentina Quarantotti, Christopher Ng, Alice H. Berger, Caterina Nardella, Laura Poliseno, Rodolfo Montironi, Mireia Castillo-Martin, Carlos Cordon-Cardo, Sabina Signoretti, Pier Paolo Pandolfi
Journal: Cancer Discovery
Cancer Discov (2015) 5 (5): 550–563.
https://doi.org/10.1158/2159-8290.CD-13-1050
Published: 03 May 2015
View article titled, Suppression of <em>CHK1</em> by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis
Open the PDF for Suppression of <em>CHK1</em> by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

A Genetic Platform to Model Sarcomagenesis from Primary Adult Mesenchymal Stem Cells

Jlenia Guarnerio, Luisa Riccardi, Riccardo Taulli, Takahiro Maeda, Guocan Wang, Robin M. Hobbs, Min Sup Song, Paolo Sportoletti, Rosa Bernardi, Roderick T. Bronson, Mireia Castillo-Martin, Carlos Cordon-Cardo, Andrea Lunardi, Pier Paolo Pandolfi
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2015) 5 (4): 396–409.
https://doi.org/10.1158/2159-8290.CD-14-1022
Published: 05 April 2015
View article titled, A Genetic Platform to Model Sarcomagenesis from Primary Adult Mesenchymal Stem Cells
Open the PDF for A Genetic Platform to Model Sarcomagenesis from Primary Adult Mesenchymal Stem Cells in another window
Includes: Supplementary data
Journal Articles

RapidCaP, a Novel GEM Model for Metastatic Prostate Cancer Analysis and Therapy, Reveals Myc as a Driver of Pten-Mutant Metastasis

Hyejin Cho, Tali Herzka, Wu Zheng, Jun Qi, John E. Wilkinson, James E. Bradner, Brian D. Robinson, Mireia Castillo-Martin, Carlos Cordon-Cardo, Lloyd C. Trotman
Journal: Cancer Discovery
Cancer Discov (2014) 4 (3): 318–333.
https://doi.org/10.1158/2159-8290.CD-13-0346
Published: 03 March 2014
View article titled, RapidCaP, a Novel GEM Model for Metastatic Prostate Cancer Analysis and Therapy, Reveals Myc as a Driver of <em>Pten</em>-Mutant Metastasis
Open the PDF for RapidCaP, a Novel GEM Model for Metastatic Prostate Cancer Analysis and Therapy, Reveals Myc as a Driver of <em>Pten</em>-Mutant Metastasis in another window
Includes: Supplementary data