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Miguel F. Sanmamed
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Journal Articles

Immunogenicity and Efficacy of Personalized Adjuvant mRNA Cancer Vaccines

Pedro Berraondo, Raquel Cuesta, Miguel F. Sanmamed, Ignacio Melero
Journal: Cancer Discovery
Cancer Discov (2024) 14 (11): 2021–2024.
https://doi.org/10.1158/2159-8290.CD-24-1196
Published: 01 November 2024
View article titled, Immunogenicity and Efficacy of Personalized Adjuvant mRNA Cancer Vaccines
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Journal Articles

CD137 (4-1BB)-Based Cancer Immunotherapy on Its 25th Anniversary

Ignacio Melero, Miguel F. Sanmamed, Javier Glez-Vaz, Carlos Luri-Rey, Jun Wang, Lieping Chen
Journal: Cancer Discovery
Cancer Discov (2023) 13 (3): 552–569.
https://doi.org/10.1158/2159-8290.CD-22-1029
Published: 01 March 2023
View article titled, CD137 (4-1BB)-Based Cancer Immunotherapy on Its 25th Anniversary
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Journal Articles

A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα, and IL-1β

Irene Olivera, Rebeca Sanz-Pamplona, Elixabet Bolaños, Inmaculada Rodriguez, Iñaki Etxeberria, Assunta Cirella, Josune Egea, Saray Garasa, Itziar Migueliz, Iñaki Eguren-Santamaria, Miguel F. Sanmamed, Javier Glez-Vaz, Arantza Azpilikueta, Maite Alvarez, María C. Ochoa, Beatrice Malacrida, David Propper, Carlos E. de Andrea, Pedro Berraondo, Frances R. Balkwill, Álvaro Teijeira, Ignacio Melero
Journal: Cancer Discovery
Cancer Discov (2022) 12 (9): 2140–2157.
https://doi.org/10.1158/2159-8290.CD-21-1115
Published: 02 September 2022
View article titled, A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα, and IL-1β
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Includes: Supplementary data
Journal Articles

A Burned-Out CD8+ T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy

Miguel F. Sanmamed, Xinxin Nie, Shruti S. Desai, Franz Villaroel-Espindola, Ti Badri, Dejian Zhao, Anthony W. Kim, Lan Ji, Tianxiang Zhang, Edward Quinlan, Xiaoxiao Cheng, Xue Han, Matthew D. Vesely, Ala F. Nassar, Jingwei Sun, Yu Zhang, Tae Kon Kim, Jun Wang, Ignacio Melero, Roy S. Herbst, Kurt A. Schalper, Lieping Chen
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (7): 1700–1715.
https://doi.org/10.1158/2159-8290.CD-20-0962
Published: 01 July 2021
View article titled, A Burned-Out CD8<sup>+</sup> T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy
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Includes: Supplementary data
Journal Articles

Paradigms on Immunotherapy Combinations with Chemotherapy

Diego Salas-Benito, José L. Pérez-Gracia, Mariano Ponz-Sarvisé, María E. Rodriguez-Ruiz, Iván Martínez-Forero, Eduardo Castañón, José M. López-Picazo, Miguel F. Sanmamed, Ignacio Melero
Journal: Cancer Discovery
Cancer Discov (2021) 11 (6): 1353–1367.
https://doi.org/10.1158/2159-8290.CD-20-1312
Published: 01 June 2021
View article titled, Paradigms on Immunotherapy Combinations with Chemotherapy
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Includes: Supplementary data
Journal Articles

Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer

Scott Gettinger, Jungmin Choi, Katherine Hastings, Anna Truini, Ila Datar, Ryan Sowell, Anna Wurtz, Weilai Dong, Guoping Cai, Mary Ann Melnick, Victor Y. Du, Joseph Schlessinger, Sarah B. Goldberg, Anne Chiang, Miguel F. Sanmamed, Ignacio Melero, Jackeline Agorreta, Luis M. Montuenga, Richard Lifton, Soldano Ferrone, Paula Kavathas, David L. Rimm, Susan M. Kaech, Kurt Schalper, Roy S. Herbst, Katerina Politi
Journal: Cancer Discovery
Cancer Discov (2017) 7 (12): 1420–1435.
https://doi.org/10.1158/2159-8290.CD-17-0593
Published: 04 December 2017
View article titled, Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer
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Includes: Supplementary data
Journal Articles

The HIF-1α Hypoxia Response in Tumor-Infiltrating T Lymphocytes Induces Functional CD137 (4-1BB) for Immunotherapy

Asís Palazón, Iván Martínez-Forero, Alvaro Teijeira, Aizea Morales-Kastresana, Carlos Alfaro, Miguel F. Sanmamed, Jose Luis Perez-Gracia, Iván Peñuelas, Sandra Hervás-Stubbs, Ana Rouzaut, Manuel Ortiz de Landázuri, Maria Jure-Kunkel, Julian Aragonés, Ignacio Melero
Journal: Cancer Discovery
Cancer Discov (2012) 2 (7): 608–623.
https://doi.org/10.1158/2159-8290.CD-11-0314
Published: 10 July 2012
View article titled, The HIF-1α Hypoxia Response in Tumor-Infiltrating T Lymphocytes Induces Functional CD137 (4-1BB) for Immunotherapy
Open the PDF for The HIF-1α Hypoxia Response in Tumor-Infiltrating T Lymphocytes Induces Functional CD137 (4-1BB) for Immunotherapy in another window
Includes: Supplementary data