1-20 of 22
Michael F. Berger
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Chromothripsis-mediated small cell lung carcinoma

Natasha Rekhtman, Sam E. Tischfield, Christopher A. Febres-Aldana, Jake June-Koo. Lee, Jason C. Chang, Benjamin O. Herzberg, Pier Selenica, Hyung Jun Woo, Chad M. Vanderbilt, Soo-Ryum Yang, Fei Xu, Anita S. Bowman, Edaise M. da Silva, Anne Marie Noronha, Diana L. Mandelker, Miika Mehine, Semanti Mukherjee, Juan Blanco-Heredia, John J. Orgera, Gouri J. Nanjangud, Marina K. Baine, Rania G. Aly, Jennifer L. Sauter, William D. Travis, Omid Savari, Andre L. Moreira, Christina J. Falcon, Francis M. Bodd, Christina E. Wilson, Jacklynn V. Sienty, Parvathy Manoj, Harsha Sridhar, Lu Wang, Noura J. Choudhury, Michael Offin, Helena A. Yu, Alvaro Quintanal-Villalonga, Michael F. Berger, Marc Ladanyi, Mark T.A. Donoghue, Jorge S. Reis-Filho, Charles M. Rudin
Journal: Cancer Discovery
Cancer Discov (2024)
https://doi.org/10.1158/2159-8290.CD-24-0286
Published: 26 August 2024
View article titled, Chromothripsis-mediated small cell lung carcinoma
Open the PDF for Chromothripsis-mediated small cell lung carcinoma in another window
Includes: Supplementary data
Journal Articles

Deep-Learning Model for Tumor-Type Prediction Using Targeted Clinical Genomic Sequencing Data

Madison Darmofal, Shalabh Suman, Gurnit Atwal, Michael Toomey, Jie-Fu Chen, Jason C. Chang, Efsevia Vakiani, Anna M. Varghese, Anoop Balakrishnan Rema, Aijazuddin Syed, Nikolaus Schultz, Michael F. Berger, Quaid Morris
Journal: Cancer Discovery
Cancer Discov (2024) 14 (6): 1064–1081.
https://doi.org/10.1158/2159-8290.CD-23-0996
Published: 03 June 2024
View article titled, Deep-Learning Model for Tumor-Type Prediction Using Targeted Clinical Genomic Sequencing Data
Open the PDF for Deep-Learning Model for Tumor-Type Prediction Using Targeted Clinical Genomic Sequencing Data in another window
Includes: Supplementary data
Journal Articles

Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer

Sarah P. Suehnholz, Moriah H. Nissan, Hongxin Zhang, Ritika Kundra, Subhiksha Nandakumar, Calvin Lu, Stephanie Carrero, Amanda Dhaneshwar, Nicole Fernandez, Benjamin W. Xu, Maria E. Arcila, Ahmet Zehir, Aijazuddin Syed, A. Rose Brannon, Julia E. Rudolph, Eder Paraiso, Paul J. Sabbatini, Ross L. Levine, Ahmet Dogan, Jianjiong Gao, Marc Ladanyi, Alexander Drilon, Michael F. Berger, David B. Solit, Nikolaus Schultz, Debyani Chakravarty
Journal: Cancer Discovery
Cancer Discov (2024) 14 (1): 49–65.
https://doi.org/10.1158/2159-8290.CD-23-0467
Published: 12 January 2024
View article titled, Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer
Open the PDF for Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer in another window
Includes: Supplementary data
Journal Articles

Molecular Characterization of Endometrial Carcinomas in Black and White Patients Reveals Disparate Drivers with Therapeutic Implications

Britta Weigelt, Antonio Marra, Pier Selenica, Eric Rios-Doria, Amir Momeni-Boroujeni, Michael F. Berger, Kanika Arora, David Nemirovsky, Alexia Iasonos, Debyani Chakravarty, Nadeem R. Abu-Rustum, Arnaud Da Cruz Paula, Kimberly Dessources, Lora H. Ellenson, Ying L. Liu, Carol Aghajanian, Carol L. Brown
Journal: Cancer Discovery
Cancer Discov (2023) 13 (11): 2356–2369.
https://doi.org/10.1158/2159-8290.CD-23-0546
Published: 01 November 2023
View article titled, Molecular Characterization of Endometrial Carcinomas in Black and White Patients Reveals Disparate Drivers with Therapeutic Implications
Open the PDF for Molecular Characterization of Endometrial Carcinomas in Black and White Patients Reveals Disparate Drivers with Therapeutic Implications in another window
Includes: Supplementary data
Journal Articles

Molecular Characterization of Acquired Resistance to KRASG12C–EGFR Inhibition in Colorectal Cancer

Rona Yaeger, Riccardo Mezzadra, Jenna Sinopoli, Yu Bian, Michelangelo Marasco, Esther Kaplun, Yijun Gao, HuiYong Zhao, Arnaud Da Cruz Paula, Yingjie Zhu, Almudena Chaves Perez, Kalyani Chadalavada, Edison Tse, Sudhir Chowdhry, Sydney Bowker, Qing Chang, Besnik Qeriqi, Britta Weigelt, Gouri J. Nanjangud, Michael F. Berger, Hirak Der-Torossian, Kenna Anderes, Nicholas D. Socci, Jinru Shia, Gregory J. Riely, Yonina R. Murciano-Goroff, Bob T. Li, James G. Christensen, Jorge S. Reis-Filho, David B. Solit, Elisa de Stanchina, Scott W. Lowe, Neal Rosen, Sandra Misale
Journal: Cancer Discovery
Cancer Discov (2023) 13 (1): 41–55.
https://doi.org/10.1158/2159-8290.CD-22-0405
Published: 09 January 2023
View article titled, Molecular Characterization of Acquired Resistance to KRAS<sup>G12C</sup>–EGFR Inhibition in Colorectal Cancer
Open the PDF for Molecular Characterization of Acquired Resistance to KRAS<sup>G12C</sup>–EGFR Inhibition in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort

Kanika Arora, Thinh N. Tran, Yelena Kemel, Miika Mehine, Ying L. Liu, Subhiksha Nandakumar, Shaleigh A. Smith, A. Rose Brannon, Irina Ostrovnaya, Konrad H. Stopsack, Pedram Razavi, Anton Safonov, Hira A. Rizvi, Matthew D. Hellmann, Joseph Vijai, Thomas C. Reynolds, James A. Fagin, Jian Carrot-Zhang, Kenneth Offit, David B. Solit, Marc Ladanyi, Nikolaus Schultz, Ahmet Zehir, Carol L. Brown, Zsofia K. Stadler, Debyani Chakravarty, Chaitanya Bandlamudi, Michael F. Berger
Journal: Cancer Discovery
Cancer Discov (2022) 12 (11): 2552–2565.
https://doi.org/10.1158/2159-8290.CD-22-0312
Published: 02 November 2022
View article titled, Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort
Open the PDF for Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort in another window
Includes: Supplementary data
Journal Articles

Cancer-Causative Mutations Occurring in Early Embryogenesis

Fresia Pareja, Ryan N. Ptashkin, David N. Brown, Fatemeh Derakhshan, Pier Selenica, Edaise M. da Silva, Andrea M. Gazzo, Arnaud Da Cruz Paula, Kelsey Breen, Ronglai Shen, Antonio Marra, Ahmet Zehir, Ryma Benayed, Michael F. Berger, Ozge Ceyhan-Birsoy, Sowmya Jairam, Margaret Sheehan, Utsav Patel, Yelena Kemel, Jacklyn Casanova-Murphy, Christopher J. Schwartz, Mahsa Vahdatinia, Elizabeth Comen, Laetitia Borsu, Xin Pei, Nadeem Riaz, David H. Abramson, Britta Weigelt, Michael F. Walsh, Anna-Katerina Hadjantonakis, Marc Ladanyi, Kenneth Offit, Zsofia K. Stadler, Mark E. Robson, Jorge S. Reis-Filho, Diana Mandelker
Journal: Cancer Discovery
Cancer Discov (2022) 12 (4): 949–957.
https://doi.org/10.1158/2159-8290.CD-21-1110
Published: 01 April 2022
View article titled, Cancer-Causative Mutations Occurring in Early Embryogenesis
Open the PDF for Cancer-Causative Mutations Occurring in Early Embryogenesis in another window
Includes: Supplementary data
Journal Articles

TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors

Emiliano Cocco, Ji Eun Lee, Srinivasaraghavan Kannan, Alison M. Schram, Helen H. Won, Sophie Shifman, Amanda Kulick, Laura Baldino, Eneda Toska, Amaia Arruabarrena-Aristorena, Srushti Kittane, Fan Wu, Yanyan Cai, Sabrina Arena, Benedetta Mussolin, Ram Kannan, Neil Vasan, Alexander N. Gorelick, Michael F. Berger, Ofra Novoplansky, Sankar Jagadeeshan, Yi Liao, Uwe Rix, Sandra Misale, Barry S. Taylor, Alberto Bardelli, Jaclyn F. Hechtman, David M. Hyman, Moshe Elkabets, Elisa de Stanchina, Chandra S. Verma, Andrea Ventura, Alexander Drilon, Maurizio Scaltriti
Journal: Cancer Discovery
Cancer Discov (2021) 11 (1): 126–141.
https://doi.org/10.1158/2159-8290.CD-20-0571
Published: 06 January 2021
View article titled, TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors
Open the PDF for TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors in another window
Includes: Supplementary data
Journal Articles

HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers

Bob T. Li, Flavia Michelini, Sandra Misale, Emiliano Cocco, Laura Baldino, Yanyan Cai, Sophie Shifman, Hai-Yan Tu, Mackenzie L. Myers, Chongrui Xu, Marissa Mattar, Inna Khodos, Megan Little, Besnik Qeriqi, Gregory Weitsman, Clare J. Wilhem, Alshad S. Lalani, Irmina Diala, Rachel A. Freedman, Nancy U. Lin, David B. Solit, Michael F. Berger, Paul R. Barber, Tony Ng, Michael Offin, James M. Isbell, David R. Jones, Helena A. Yu, Sheeno Thyparambil, Wei-Li Liao, Anuja Bhalkikar, Fabiola Cecchi, David M. Hyman, Jason S. Lewis, Darren J. Buonocore, Alan L. Ho, Vicky Makker, Jorge S. Reis-Filho, Pedram Razavi, Maria E. Arcila, Mark G. Kris, John T. Poirier, Ronglai Shen, Junji Tsurutani, Gary A. Ulaner, Elisa de Stanchina, Neal Rosen, Charles M. Rudin, Maurizio Scaltriti
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (5): 674–687.
https://doi.org/10.1158/2159-8290.CD-20-0215
Published: 01 May 2020
View article titled, HER2-Mediated Internalization of Cytotoxic Agents in <em>ERBB2</em> Amplified or Mutant Lung Cancers
Open the PDF for HER2-Mediated Internalization of Cytotoxic Agents in <em>ERBB2</em> Amplified or Mutant Lung Cancers in another window
Includes: Supplementary data
Journal Articles

Correction: An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer

Ariella B. Hanker, Monica Red Brewer, Jonathan H. Sheehan, James P. Koch, Gregory R. Sliwoski, Rebecca Nagy, Richard Lanman, Michael F. Berger, David M. Hyman, David B. Solit, Jie He, Vincent Miller, Richard E. Cutler, Jr, Alshad S. Lalani, Darren Cross, Christine M. Lovly, Jens Meiler, Carlos L. Arteaga
Journal: Cancer Discovery
Cancer Discov (2019) 9 (2): 303.
https://doi.org/10.1158/2159-8290.CD-18-1515
Published: 08 February 2019
View article titled, Correction: An Acquired <em>HER2</em><sup>T798I</sup> Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer
Open the PDF for Correction: An Acquired <em>HER2</em><sup>T798I</sup> Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer in another window
Journal Articles

EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer

Francisco Sanchez-Vega, Jaclyn F. Hechtman, Pau Castel, Geoffrey Y. Ku, Yaelle Tuvy, Helen Won, Christopher J. Fong, Nancy Bouvier, Gouri J. Nanjangud, Joanne Soong, Efsevia Vakiani, Mark Schattner, David P. Kelsen, Robert A. Lefkowitz, Karen Brown, Mario E. Lacouture, Marinela Capanu, Marissa Mattar, Besnik Qeriqi, Fabiola Cecchi, Yuan Tian, Todd Hembrough, Rebecca J. Nagy, Richard B. Lanman, Steven M. Larson, Neeta Pandit-Taskar, Heiko Schöder, Christine A. Iacobuzio-Donahue, David H. Ilson, Wolfgang A. Weber, Michael F. Berger, Elisa de Stanchina, Barry S. Taylor, Jason S. Lewis, David B. Solit, Jorge A. Carrasquillo, Maurizio Scaltriti, Nikolaus Schultz, Yelena Y. Janjigian
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2019) 9 (2): 199–209.
https://doi.org/10.1158/2159-8290.CD-18-0598
Published: 08 February 2019
View article titled, <em>EGFR</em> and <em>MET</em> Amplifications Determine Response to HER2 Inhibition in <em>ERBB2</em>-Amplified Esophagogastric Cancer
Open the PDF for <em>EGFR</em> and <em>MET</em> Amplifications Determine Response to HER2 Inhibition in <em>ERBB2</em>-Amplified Esophagogastric Cancer in another window
Includes: Supplementary data
Journal Articles

Accelerating Discovery of Functional Mutant Alleles in Cancer

Matthew T. Chang, Tripti Shrestha Bhattarai, Alison M. Schram, Craig M. Bielski, Mark T.A. Donoghue, Philip Jonsson, Debyani Chakravarty, Sarah Phillips, Cyriac Kandoth, Alexander Penson, Alexander Gorelick, Tambudzai Shamu, Swati Patel, Christopher Harris, JianJiong Gao, Selcuk Onur Sumer, Ritika Kundra, Pedram Razavi, Bob T. Li, Dalicia N. Reales, Nicholas D. Socci, Gowtham Jayakumaran, Ahmet Zehir, Ryma Benayed, Maria E. Arcila, Sarat Chandarlapaty, Marc Ladanyi, Nikolaus Schultz, José Baselga, Michael F. Berger, Neal Rosen, David B. Solit, David M. Hyman, Barry S. Taylor
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (2): 174–183.
https://doi.org/10.1158/2159-8290.CD-17-0321
Published: 04 February 2018
View article titled, Accelerating Discovery of Functional Mutant Alleles in Cancer
Open the PDF for Accelerating Discovery of Functional Mutant Alleles in Cancer in another window
Includes: Supplementary data
Journal Articles

Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer

Yelena Y. Janjigian, Francisco Sanchez-Vega, Philip Jonsson, Walid K. Chatila, Jaclyn F. Hechtman, Geoffrey Y. Ku, Jamie C. Riches, Yaelle Tuvy, Ritika Kundra, Nancy Bouvier, Efsevia Vakiani, Jianjiong Gao, Zachary J. Heins, Benjamin E. Gross, David P. Kelsen, Liying Zhang, Vivian E. Strong, Mark Schattner, Hans Gerdes, Daniel G. Coit, Manjit Bains, Zsofia K. Stadler, Valerie W. Rusch, David R. Jones, Daniela Molena, Jinru Shia, Mark E. Robson, Marinela Capanu, Sumit Middha, Ahmet Zehir, David M. Hyman, Maurizio Scaltriti, Marc Ladanyi, Neal Rosen, David H. Ilson, Michael F. Berger, Laura Tang, Barry S. Taylor, David B. Solit, Nikolaus Schultz
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (1): 49–58.
https://doi.org/10.1158/2159-8290.CD-17-0787
Published: 07 January 2018
View article titled, Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer
Open the PDF for Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer in another window
Includes: Supplementary data
Journal Articles

A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion–Positive Solid Tumors

Alexander Drilon, Ramamoorthy Nagasubramanian, James F. Blake, Nora Ku, Brian B. Tuch, Kevin Ebata, Steve Smith, Veronique Lauriault, Gabrielle R. Kolakowski, Barbara J. Brandhuber, Paul D. Larsen, Karyn S. Bouhana, Shannon L. Winski, Robyn Hamor, Wen-I Wu, Andrew Parker, Tony H. Morales, Francis X. Sullivan, Walter E. DeWolf, Lance A. Wollenberg, Paul R. Gordon, Dorothea N. Douglas-Lindsay, Maurizio Scaltriti, Ryma Benayed, Sandeep Raj, Bethany Hanusch, Alison M. Schram, Philip Jonsson, Michael F. Berger, Jaclyn F. Hechtman, Barry S. Taylor, Steve Andrews, S. Michael Rothenberg, David M. Hyman
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (9): 963–972.
https://doi.org/10.1158/2159-8290.CD-17-0507
Published: 31 August 2017
View article titled, A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion–Positive Solid Tumors
Open the PDF for A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion–Positive Solid Tumors in another window
Includes: Supplementary data
Journal Articles

AACR Project GENIE: Powering Precision Medicine through an International Consortium

The AACR Project GENIE Consortium, The AACR Project GENIE Consortium, Fabrice André, Monica Arnedos, Alexander S. Baras, José Baselga, Philippe L. Bedard, Michael F. Berger, Mariska Bierkens, Fabien Calvo, Ethan Cerami, Debyani Chakravarty, Kristen K. Dang, Nancy E. Davidson, Catherine Del Vecchio Fitz, Semih Dogan, Raymond N. DuBois, Matthew D. Ducar, P. Andrew Futreal, Jianjiong Gao, Francisco Garcia, Stu Gardos, Christopher D. Gocke, Benjamin E. Gross, Justin Guinney, Zachary J. Heins, Stephanie Hintzen, Hugo Horlings, Jan Hudeček, David M. Hyman, Suzanne Kamel-Reid, Cyriac Kandoth, Walter Kinyua, Priti Kumari, Ritika Kundra, Marc Ladanyi, Céline Lefebvre, Michele L. LeNoue-Newton, Eva M. Lepisto, Mia A. Levy, Neal I. Lindeman, James Lindsay, David Liu, Zhibin Lu, Laura E. MacConaill, Ian Maurer, David S. Maxwell, Gerrit A. Meijer, Funda Meric-Bernstam, Christine M. Micheel, Clinton Miller, Gordon Mills, Nathanael D. Moore, Petra M. Nederlof, Larsson Omberg, John A. Orechia, Ben Ho Park, Trevor J. Pugh, Brendan Reardon, Barrett J. Rollins, Mark J. Routbort, Charles L. Sawyers, Deborah Schrag, Nikolaus Schultz, Kenna R Mills Shaw, Priyanka Shivdasani, Lillian L. Siu, David B. Solit, Gabe S. Sonke, Jean Charles Soria, Parin Sripakdeevong, Natalie H. Stickle, Thomas P. Stricker, Shawn M. Sweeney, Barry S. Taylor, Jelle J. ten Hoeve, Stacy B. Thomas, Eliezer M. Van Allen, Laura J. Van 'T Veer, Tony van de Velde, Harm van Tinteren, Victor E. Velculescu, Carl Virtanen, Emile E. Voest, Lucy L. Wang, Chetna Wathoo, Stuart Watt, Celeste Yu, Thomas V. Yu, Emily Yu, Ahmet Zehir, Hongxin Zhang
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (8): 818–831.
https://doi.org/10.1158/2159-8290.CD-17-0151
Published: 01 August 2017
View article titled, AACR Project GENIE: Powering Precision Medicine through an International Consortium
Open the PDF for AACR Project GENIE: Powering Precision Medicine through an International Consortium in another window
Includes: Supplementary data
Journal Articles

Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies

Emmet J. Jordan, Hyunjae R. Kim, Maria E. Arcila, David Barron, Debyani Chakravarty, JianJiong Gao, Matthew T. Chang, Andy Ni, Ritika Kundra, Philip Jonsson, Gowtham Jayakumaran, Sizhi Paul Gao, Hannah C. Johnsen, Aphrothiti J. Hanrahan, Ahmet Zehir, Natasha Rekhtman, Michelle S. Ginsberg, Bob T. Li, Helena A. Yu, Paul K. Paik, Alexander Drilon, Matthew D. Hellmann, Dalicia N. Reales, Ryma Benayed, Valerie W. Rusch, Mark G. Kris, Jamie E. Chaft, José Baselga, Barry S. Taylor, Nikolaus Schultz, Charles M. Rudin, David M. Hyman, Michael F. Berger, David B. Solit, Marc Ladanyi, Gregory J. Riely
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (6): 596–609.
https://doi.org/10.1158/2159-8290.CD-16-1337
Published: 01 June 2017
View article titled, Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies
Open the PDF for Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies in another window
Includes: Supplementary data
Journal Articles

An Acquired HER2 T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer

Ariella B. Hanker, Monica Red Brewer, Jonathan H. Sheehan, James P. Koch, Gregory R. Sliwoski, Rebecca Nagy, Richard Lanman, Michael F. Berger, David M. Hyman, David B. Solit, Jie He, Vincent Miller, Richard E. Cutler, Jr, Alshad S. Lalani, Darren Cross, Christine M. Lovly, Jens Meiler, Carlos L. Arteaga
Journal: Cancer Discovery
Cancer Discov (2017) 7 (6): 575–585.
https://doi.org/10.1158/2159-8290.CD-16-1431
Published: 01 June 2017
View article titled, An Acquired <em>HER2</em> <sup>T798I</sup> Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer
Open the PDF for An Acquired <em>HER2</em> <sup>T798I</sup> Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Response to MET Inhibitors in Patients with Stage IV Lung Adenocarcinomas Harboring MET Mutations Causing Exon 14 Skipping

Paul K. Paik, Alexander Drilon, Pang-Dian Fan, Helena Yu, Natasha Rekhtman, Michelle S. Ginsberg, Laetitia Borsu, Nikolaus Schultz, Michael F. Berger, Charles M. Rudin, Marc Ladanyi
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2015) 5 (8): 842–849.
https://doi.org/10.1158/2159-8290.CD-14-1467
Published: 03 August 2015
View article titled, Response to MET Inhibitors in Patients with Stage IV Lung Adenocarcinomas Harboring <em>MET</em> Mutations Causing Exon 14 Skipping
Open the PDF for Response to MET Inhibitors in Patients with Stage IV Lung Adenocarcinomas Harboring <em>MET</em> Mutations Causing Exon 14 Skipping in another window
Includes: Supplementary data
Journal Articles

Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases

Paul K. Paik, Ronglai Shen, Helen Won, Natasha Rekhtman, Lu Wang, Camelia S. Sima, Arshi Arora, Venkatraman Seshan, Marc Ladanyi, Michael F. Berger, Mark G. Kris
Journal: Cancer Discovery
Cancer Discov (2015) 5 (6): 610–621.
https://doi.org/10.1158/2159-8290.CD-14-1129
Published: 01 June 2015
View article titled, Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases
Open the PDF for Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases in another window
Includes: Supplementary data
Journal Articles

Synthetic Lethality in ATM-Deficient RAD50-Mutant Tumors Underlies Outlier Response to Cancer Therapy

Hikmat Al-Ahmadie, Gopa Iyer, Marcel Hohl, Saurabh Asthana, Akiko Inagaki, Nikolaus Schultz, Aphrothiti J. Hanrahan, Sasinya N. Scott, A. Rose Brannon, Gregory C. McDermott, Mono Pirun, Irina Ostrovnaya, Philip Kim, Nicholas D. Socci, Agnes Viale, Gary K. Schwartz, Victor Reuter, Bernard H. Bochner, Jonathan E. Rosenberg, Dean F. Bajorin, Michael F. Berger, John H.J. Petrini, David B. Solit, Barry S. Taylor
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2014) 4 (9): 1014–1021.
https://doi.org/10.1158/2159-8290.CD-14-0380
Published: 01 September 2014
View article titled, Synthetic Lethality in ATM-Deficient <em>RAD50</em>-Mutant Tumors Underlies Outlier Response to Cancer Therapy
Open the PDF for Synthetic Lethality in ATM-Deficient <em>RAD50</em>-Mutant Tumors Underlies Outlier Response to Cancer Therapy in another window
Includes: Supplementary data