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Michael D. Taylor
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Journal Articles

The Virtual Child

Richard J. Gilbertson, Sam Behjati, Anna-Lisa Böttcher, Marianne E. Bronner, Matthew Burridge, Henrick Clausing, Harry Clifford, Tracey Danaher, Laura K. Donovan, Jarno Drost, Alexander M.M. Eggermont, Chris Emerson, Mona G. Flores, Petra Hamerlik, Nada Jabado, Andrew Jones, Henrick Kaessmann, Claudia L. Kleinman, Marcel Kool, Lena M. Kutscher, Gavin Lindberg, Emily Linnane, John C. Marioni, John M. Maris, Michelle Monje, Alexandra Macaskill, Steven Niederer, Paul A. Northcott, Elizabeth Peeters, Willemijn Plieger-van Solkema, Liane Preußner, Anne C. Rios, Karsten Rippe, Peter Sandford, Nikolaos G. Sgourakis, Adam Shlien, Pete Smith, Karin Straathof, Patrick J. Sullivan, Mario L. Suvà, Michael D. Taylor, Emma Thompson, Roser Vento-Tormo, Brandon J. Wainwright, Robert J. Wechsler-Reya, Frank Westermann, Shannon Winslade, Bissan Al-Lazikani, Stefan M. Pfister
Journal: Cancer Discovery
Cancer Discov (2024) 14 (4): 663–668.
https://doi.org/10.1158/2159-8290.CD-23-1500
Published: 04 April 2024
View articletitled, The Virtual Child
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Journal Articles

Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma

Zengpanpan Ye, Xiaolin Ai, Kailin Yang, Zhengnan Yang, Fan Fei, Xiaoling Liao, Zhixin Qiu, Ryan C. Gimple, Huairui Yuan, Hao Huang, Yanqiu Gong, Chaoxin Xiao, Jing Yue, Liang Huang, Olivier Saulnier, Wei Wang, Peidong Zhang, Lunzhi Dai, Xin Wang, Xiuxing Wang, Young Ha Ahn, Chao You, Jianguo Xu, Xiaoxiao Wan, Michael D. Taylor, Linjie Zhao, Jeremy N. Rich, Shengtao Zhou
Journal: Cancer Discovery
Cancer Discov (2023) 13 (4): 974–1001.
https://doi.org/10.1158/2159-8290.CD-22-0455
Published: 03 April 2023
View articletitled, Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma
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Includes: Supplementary data
Journal Articles

Mutations in the RAS/MAPK Pathway Drive Replication Repair–Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition

Brittany B. Campbell, Melissa A. Galati, Simone C. Stone, Alexandra N. Riemenschneider, Melissa Edwards, Sumedha Sudhaman, Robert Siddaway, Martin Komosa, Nuno M. Nunes, Liana Nobre, A. Sorana Morrissy, Matthew Zatzman, Michal Zapotocky, Lazar Joksimovic, Sangeetha N. Kalimuthu, David Samuel, Gary Mason, Eric Bouffet, Daniel A. Morgenstern, Melyssa Aronson, Carol Durno, David Malkin, John M. Maris, Michael D. Taylor, Adam Shlien, Trevor J. Pugh, Pamela S. Ohashi, Cynthia E. Hawkins, Uri Tabori
Journal: Cancer Discovery
Cancer Discov (2021) 11 (6): 1454–1467.
https://doi.org/10.1158/2159-8290.CD-20-1050
Published: 01 June 2021
View articletitled, Mutations in the RAS/MAPK Pathway Drive Replication Repair–Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition
Open the PDF for Mutations in the RAS/MAPK Pathway Drive Replication Repair–Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition in another window
Includes: Supplementary data
Journal Articles

DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells

Jiil Chung, Yosef E. Maruvka, Sumedha Sudhaman, Jacalyn Kelly, Nicholas J. Haradhvala, Vanessa Bianchi, Melissa Edwards, Victoria J. Forster, Nuno M. Nunes, Melissa A. Galati, Martin Komosa, Shriya Deshmukh, Vanja Cabric, Scott Davidson, Matthew Zatzman, Nicholas Light, Reid Hayes, Ledia Brunga, Nathaniel D. Anderson, Ben Ho, Karl P. Hodel, Robert Siddaway, A. Sorana Morrissy, Daniel C. Bowers, Valérie Larouche, Annika Bronsema, Michael Osborn, Kristina A. Cole, Enrico Opocher, Gary Mason, Gregory A. Thomas, Ben George, David S. Ziegler, Scott Lindhorst, Magimairajan Vanan, Michal Yalon-Oren, Alyssa T. Reddy, Maura Massimino, Patrick Tomboc, An Van Damme, Alexander Lossos, Carol Durno, Melyssa Aronson, Daniel A. Morgenstern, Eric Bouffet, Annie Huang, Michael D. Taylor, Anita Villani, David Malkin, Cynthia E. Hawkins, Zachary F. Pursell, Adam Shlien, Thomas A. Kunkel, Gad Getz, Uri Tabori
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2021) 11 (5): 1176–1191.
https://doi.org/10.1158/2159-8290.CD-20-0790
Published: 01 May 2021
View articletitled, DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells
Open the PDF for DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells in another window
Includes: Supplementary data
Journal Articles

H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone

Sima Khazaei, Nicolas De Jay, Shriya Deshmukh, Liam D. Hendrikse, Wajih Jawhar, Carol C.L. Chen, Leonie G. Mikael, Damien Faury, Dylan M. Marchione, Joel Lanoix, Éric Bonneil, Takeaki Ishii, Siddhant U. Jain, Kateryna Rossokhata, Tianna S. Sihota, Robert Eveleigh, Véronique Lisi, Ashot S. Harutyunyan, Sungmi Jung, Jason Karamchandani, Brendan C. Dickson, Robert Turcotte, Jay S. Wunder, Pierre Thibault, Peter W. Lewis, Benjamin A. Garcia, Stephen C. Mack, Michael D. Taylor, Livia Garzia, Claudia L. Kleinman, Nada Jabado
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2020) 10 (12): 1968–1987.
https://doi.org/10.1158/2159-8290.CD-20-0461
Published: 01 December 2020
View articletitled, H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
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Includes: Supplementary data
Journal Articles

ATM Regulates 3-Methylpurine-DNA Glycosylase and Promotes Therapeutic Resistance to Alkylating Agents

Sameer Agnihotri, Kelly Burrell, Pawel Buczkowicz, Marc Remke, Brian Golbourn, Yevgen Chornenkyy, Aaron Gajadhar, Nestor A. Fernandez, Ian D. Clarke, Mark S. Barszczyk, Sanja Pajovic, Christian Ternamian, Renee Head, Nesrin Sabha, Robert W. Sobol, Michael D. Taylor, James T. Rutka, Chris Jones, Peter B. Dirks, Gelareh Zadeh, Cynthia Hawkins
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2014) 4 (10): 1198–1213.
https://doi.org/10.1158/2159-8290.CD-14-0157
Published: 30 September 2014
View articletitled, ATM Regulates 3-Methylpurine-DNA Glycosylase and Promotes Therapeutic Resistance to Alkylating Agents
Open the PDF for ATM Regulates 3-Methylpurine-DNA Glycosylase and Promotes Therapeutic Resistance to Alkylating Agents in another window
Includes: Supplementary data