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Markus J. van Roosmalen
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Journal Articles

Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells

Ilana Struys, Carolina Velázquez, Joske Ubels, Charlotte L. LeJeune, Markus J. van Roosmalen, Axel K.M. Rosendahl Huber, Anais J.C.N. van Leeuwen, Wouter Bossuyt, Bernard Thienpont, Thierry Voet, Kristel Van Calsteren, Liesbeth Lenaerts, Ruben van Boxtel, Frédéric Amant
Journal: Cancer Discovery
Cancer Discov OF1–OF10.
https://doi.org/10.1158/2159-8290.CD-24-1368
Published: 20 March 2025
View articletitled, Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Open the PDF for Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells in another window
Includes: Supplementary data
Journal Articles

Elevated Mutational Age in Blood of Children Treated for Cancer Contributes to Therapy-Related Myeloid Neoplasms

Eline J.M. Bertrums, Axel K.M. Rosendahl Huber, Jurrian K. de Kanter, Arianne M. Brandsma, Anaïs J.C.N. van Leeuwen, Mark Verheul, Marry M. van den Heuvel-Eibrink, Rurika Oka, Markus J. van Roosmalen, Hester A. de Groot-Kruseman, C. Michel Zwaan, Bianca F. Goemans, Ruben van Boxtel
Journal: Cancer Discovery
Cancer Discov (2022) 12 (8): 1860–1872.
https://doi.org/10.1158/2159-8290.CD-22-0120
Published: 05 August 2022
View articletitled, Elevated Mutational Age in Blood of Children Treated for Cancer Contributes to Therapy-Related Myeloid Neoplasms
Open the PDF for Elevated Mutational Age in Blood of Children Treated for Cancer Contributes to Therapy-Related Myeloid Neoplasms in another window
Includes: Supplementary data