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Mark A. Rubin
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Journal Articles

OncoLoop: A Network-Based Precision Cancer Medicine Framework

Alessandro Vasciaveo, Juan Martín Arriaga, Francisca Nunes de Almeida, Min Zou, Eugene F. Douglass, Jr, Florencia Picech, Maho Shibata, Antonio Rodriguez-Calero, Simone de Brot, Antonina Mitrofanova, Chee Wai Chua, Charles Karan, Ronald Realubit, Sergey Pampou, Jaime Y. Kim, Stephanie N. Afari, Timur Mukhammadov, Luca Zanella, Eva Corey, Mariano J. Alvarez, Mark A. Rubin, Michael M. Shen, Andrea Califano, Cory Abate-Shen
Journal: Cancer Discovery
Cancer Discov (2023) 13 (2): 386–409.
https://doi.org/10.1158/2159-8290.CD-22-0342
Published: 06 February 2023
View article titled, OncoLoop: A Network-Based Precision Cancer Medicine Framework
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Includes: Supplementary data
Journal Articles

NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation

Alexandros Papachristodoulou, Antonio Rodriguez-Calero, Sukanya Panja, Elizabeth Margolskee, Renu K. Virk, Teresa A. Milner, Luis Pina Martina, Jaime Y. Kim, Matteo Di Bernardo, Alanna B. Williams, Elvis A. Maliza, Joseph M. Caputo, Christopher Haas, Vinson Wang, Guarionex Joel De Castro, Sven Wenske, Hanina Hibshoosh, James M. McKiernan, Michael M. Shen, Mark A. Rubin, Antonina Mitrofanova, Aditya Dutta, Cory Abate-Shen
Journal: Cancer Discovery
Cancer Discov (2021) 11 (9): 2316–2333.
https://doi.org/10.1158/2159-8290.CD-20-1765
Published: 01 September 2021
View article titled, NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation
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Includes: Supplementary data
Journal Articles

TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis

Pilar M. Dominguez, Hussein Ghamlouch, Wojciech Rosikiewicz, Parveen Kumar, Wendy Béguelin, Lorena Fontán, Martín A. Rivas, Patrycja Pawlikowska, Marine Armand, Enguerran Mouly, Miguel Torres-Martin, Ashley S. Doane, María T. Calvo Fernandez, Matt Durant, Veronique Della-Valle, Matt Teater, Luisa Cimmino, Nathalie Droin, Saber Tadros, Samaneh Motanagh, Alan H. Shih, Mark A. Rubin, Wayne Tam, Iannis Aifantis, Ross L. Levine, Olivier Elemento, Giorgio Inghirami, Michael R. Green, Maria E. Figueroa, Olivier A. Bernard, Said Aoufouchi, Sheng Li, Rita Shaknovich, Ari M. Melnick
Journal: Cancer Discovery
Cancer Discov (2018) 8 (12): 1632–1653.
https://doi.org/10.1158/2159-8290.CD-18-0657
Published: 03 December 2018
View article titled, TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis
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Includes: Supplementary data
Journal Articles

Prostate Power Play: Does Pik3ca Accelerate Pten-Deficient Cancer Progression?

Joanna Triscott, Mark A. Rubin
Journal: Cancer Discovery
Cancer Discov (2018) 8 (6): 682–685.
https://doi.org/10.1158/2159-8290.CD-18-0369
Published: 31 May 2018
View article titled, Prostate Power Play: Does <em>Pik3ca</em> Accelerate <em>Pten</em>-Deficient Cancer Progression?
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Journal Articles

Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations

Franklin W. Huang, Juan Miguel Mosquera, Andrea Garofalo, Coyin Oh, Maria Baco, Ali Amin-Mansour, Bokang Rabasha, Samira Bahl, Stephanie A. Mullane, Brian D. Robinson, Saud Aldubayan, Francesca Khani, Beerinder Karir, Eejung Kim, Jeremy Chimene-Weiss, Matan Hofree, Alessandro Romanel, Joseph R. Osborne, Jong Wook Kim, Gissou Azabdaftari, Anna Woloszynska-Read, Karen Sfanos, Angelo M. De Marzo, Francesca Demichelis, Stacey Gabriel, Eliezer M. Van Allen, Jill Mesirov, Pablo Tamayo, Mark A. Rubin, Isaac J. Powell, Levi A. Garraway
Journal: Cancer Discovery
Cancer Discov (2017) 7 (9): 973–983.
https://doi.org/10.1158/2159-8290.CD-16-0960
Published: 31 August 2017
View article titled, Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function <em>ERF</em> Mutations
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Includes: Supplementary data
Journal Articles

Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer

Min Zou, Roxanne Toivanen, Antonina Mitrofanova, Nicolas Floch, Sheida Hayati, Yanping Sun, Clémentine Le Magnen, Daniel Chester, Elahe A. Mostaghel, Andrea Califano, Mark A. Rubin, Michael M. Shen, Cory Abate-Shen
Journal: Cancer Discovery
Cancer Discov (2017) 7 (7): 736–749.
https://doi.org/10.1158/2159-8290.CD-16-1174
Published: 05 July 2017
View article titled, Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Chantal Pauli, Benjamin D. Hopkins, Davide Prandi, Reid Shaw, Tarcisio Fedrizzi, Andrea Sboner, Verena Sailer, Michael Augello, Loredana Puca, Rachele Rosati, Terra J. McNary, Yelena Churakova, Cynthia Cheung, Joanna Triscott, David Pisapia, Rema Rao, Juan Miguel Mosquera, Brian Robinson, Bishoy M. Faltas, Brooke E. Emerling, Vijayakrishna K. Gadi, Brady Bernard, Olivier Elemento, Himisha Beltran, Francesca Demichelis, Christopher J. Kemp, Carla Grandori, Lewis C. Cantley, Mark A. Rubin
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2017) 7 (5): 462–477.
https://doi.org/10.1158/2159-8290.CD-16-1154
Published: 30 April 2017
View article titled, Personalized <em>In Vitro</em> and <em>In Vivo</em> Cancer Models to Guide Precision Medicine
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Includes: Supplementary data
Journal Articles

The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer

Jennifer L. Bishop, Daksh Thaper, Sepideh Vahid, Alastair Davies, Kirsi Ketola, Hidetoshi Kuruma, Randy Jama, Ka Mun Nip, Arkhjamil Angeles, Fraser Johnson, Alexander W. Wyatt, Ladan Fazli, Martin E. Gleave, Dong Lin, Mark A. Rubin, Colin C. Collins, Yuzhuo Wang, Himisha Beltran, Amina Zoubeidi
Journal: Cancer Discovery
Cancer Discov (2017) 7 (1): 54–71.
https://doi.org/10.1158/2159-8290.CD-15-1263
Published: 05 January 2017
View article titled, The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer
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Includes: Supplementary data
Journal Articles

Insights into the Mechanism of Organ-Specific Cancer Metastasis

Mark A. Rubin
Journal: Cancer Discovery
Cancer Discov (2014) 4 (11): 1262–1264.
https://doi.org/10.1158/2159-8290.CD-14-1075
Published: 01 November 2014
View article titled, Insights into the Mechanism of Organ-Specific Cancer Metastasis
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Journal Articles

Genome-wide DNA Methylation Events in TMPRSS2–ERG Fusion-Negative Prostate Cancers Implicate an EZH2-Dependent Mechanism with miR-26a Hypermethylation

Stefan T. Börno, Axel Fischer, Martin Kerick, Maria Fälth, Mark Laible, Jan C. Brase, Ruprecht Kuner, Andreas Dahl, Christina Grimm, Behnam Sayanjali, Melanie Isau, Christina Röhr, Andrea Wunderlich, Bernd Timmermann, Rainer Claus, Christoph Plass, Markus Graefen, Ronald Simon, Francesca Demichelis, Mark A. Rubin, Guido Sauter, Thorsten Schlomm, Holger Sültmann, Hans Lehrach, Michal R. Schweiger
Journal: Cancer Discovery
Cancer Discov (2012) 2 (11): 1024–1035.
https://doi.org/10.1158/2159-8290.CD-12-0041
Published: 11 November 2012
View article titled, Genome-wide DNA Methylation Events in <em>TMPRSS2–ERG</em> Fusion-Negative Prostate Cancers Implicate an EZH2-Dependent Mechanism with <em>miR-26a</em> Hypermethylation
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Includes: Supplementary data
Journal Articles

Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets

Himisha Beltran, David S. Rickman, Kyung Park, Sung Suk Chae, Andrea Sboner, Theresa Y. MacDonald, Yuwei Wang, Karen L. Sheikh, Stéphane Terry, Scott T. Tagawa, Rajiv Dhir, Joel B. Nelson, Alexandre de la Taille, Yves Allory, Mark B. Gerstein, Sven Perner, Kenneth J. Pienta, Arul M. Chinnaiyan, Yuzhuo Wang, Colin C. Collins, Martin E. Gleave, Francesca Demichelis, David M. Nanus, Mark A. Rubin
Journal: Cancer Discovery
Cancer Discov (2011) 1 (6): 487–495.
https://doi.org/10.1158/2159-8290.CD-11-0130
Published: 16 November 2011
View article titled, Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets
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Includes: Supplementary data
Journal Articles

Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

Xiao-Song Wang, Sunita Shankar, Saravana M. Dhanasekaran, Bushra Ateeq, Atsuo T. Sasaki, Xiaojun Jing, Daniel Robinson, Qi Cao, John R. Prensner, Anastasia K. Yocum, Rui Wang, Daniel F. Fries, Bo Han, Irfan A. Asangani, Xuhong Cao, Yong Li, Gilbert S. Omenn, Dorothee Pflueger, Anuradha Gopalan, Victor E. Reuter, Emily Rose Kahoud, Lewis C. Cantley, Mark A. Rubin, Nallasivam Palanisamy, Sooryanarayana Varambally, Arul M. Chinnaiyan
Journal: Cancer Discovery
Cancer Discov (2011) 1 (1): 35–43.
https://doi.org/10.1158/2159-8274.CD-10-0022
Published: 01 June 2011
View article titled, Characterization of <em>KRAS</em> Rearrangements in Metastatic Prostate Cancer
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Includes: Supplementary data