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Journal Articles

Single-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer

Aislyn Schalck, Donastas Sakellariou-Thompson, Marie-Andrée Forget, Emi Sei, Tara G. Hughes, Alexandre Reuben, Shanshan Bai, Min Hu, Tapsi Kumar, Mark W. Hurd, Matthew H.G. Katz, Ching-Wei D. Tzeng, Shubham Pant, Milind Javle, David R. Fogelman, Anirban Maitra, Cara L. Haymaker, Michael P. Kim, Nicholas E. Navin, Chantale Bernatchez
Journal: Cancer Discovery
Cancer Discov (2022) 12 (10): 2330–2349.
https://doi.org/10.1158/2159-8290.CD-21-1248
Published: 05 October 2022
View article titled, Single-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer
Open the PDF for Single-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma

Shelly Kalaora, Yochai Wolf, Tali Feferman, Eilon Barnea, Erez Greenstein, Dan Reshef, Itay Tirosh, Alexandre Reuben, Sushant Patkar, Ronen Levy, Juliane Quinkhardt, Tana Omokoko, Nouar Qutob, Ofra Golani, Jianhua Zhang, Xizeng Mao, Xingzhi Song, Chantale Bernatchez, Cara Haymaker, Marie-Andrée Forget, Caitlin Creasy, Polina Greenberg, Brett W. Carter, Zachary A. Cooper, Steven A. Rosenberg, Michal Lotem, Ugur Sahin, Guy Shakhar, Eytan Ruppin, Jennifer A. Wargo, Nir Friedman, Arie Admon, Yardena Samuels
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2018) 8 (11): 1366–1375.
https://doi.org/10.1158/2159-8290.CD-17-1418
Published: 01 November 2018
View article titled, Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma
Open the PDF for Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma in another window
Includes: Multimedia, Supplementary data
Journal Articles

TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence

Alexandre Reuben, Rachel Gittelman, Jianjun Gao, Jiexin Zhang, Erik C. Yusko, Chang-Jiun Wu, Ryan Emerson, Jianhua Zhang, Christopher Tipton, Jun Li, Kelly Quek, Vancheswaran Gopalakrishnan, Runzhe Chen, Luis M. Vence, Tina Cascone, Marissa Vignali, Junya Fujimoto, Jaime Rodriguez-Canales, Edwin R. Parra, Latasha D. Little, Curtis Gumbs, Marie-Andrée Forget, Lorenzo Federico, Cara Haymaker, Carmen Behrens, Sharon Benzeno, Chantale Bernatchez, Boris Sepesi, Don L. Gibbons, Jennifer A. Wargo, William N. William, Jr, Stephen Swisher, John V. Heymach, Harlan Robins, J. Jack Lee, Padmanee Sharma, James P. Allison, P. Andrew Futreal, Ignacio I. Wistuba, Jianjun Zhang
Journal: Cancer Discovery
Cancer Discov (2017) 7 (10): 1088–1097.
https://doi.org/10.1158/2159-8290.CD-17-0256
Published: 02 October 2017
View article titled, TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence
Open the PDF for TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence in another window
Includes: Supplementary data
Journal Articles

Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy

Weiyi Peng, Jie Qing Chen, Chengwen Liu, Shruti Malu, Caitlin Creasy, Michael T. Tetzlaff, Chunyu Xu, Jodi A. McKenzie, Chunlei Zhang, Xiaoxuan Liang, Leila J. Williams, Wanleng Deng, Guo Chen, Rina Mbofung, Alexander J. Lazar, Carlos A. Torres-Cabala, Zachary A. Cooper, Pei-Ling Chen, Trang N. Tieu, Stefani Spranger, Xiaoxing Yu, Chantale Bernatchez, Marie-Andree Forget, Cara Haymaker, Rodabe Amaria, Jennifer L. McQuade, Isabella C. Glitza, Tina Cascone, Haiyan S. Li, Lawrence N. Kwong, Timothy P. Heffernan, Jianhua Hu, Roland L. Bassett, Jr, Marcus W. Bosenberg, Scott E. Woodman, Willem W. Overwijk, Gregory Lizée, Jason Roszik, Thomas F. Gajewski, Jennifer A. Wargo, Jeffrey E. Gershenwald, Laszlo Radvanyi, Michael A. Davies, Patrick Hwu
Journal: Cancer Discovery
Series: Author Choice
Cancer Discov (2016) 6 (2): 202–216.
https://doi.org/10.1158/2159-8290.CD-15-0283
Published: 04 February 2016
View article titled, Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy
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Includes: Supplementary data